Sentences with phrase «complex cellular processes»
Identifying these functional couplings is an important step in the understanding of higher level mechanisms performed by complex cellular processes.
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The presence of calcium inside the cell, Malenka and Nicoll believed, acts like a cellular starting gun, setting off a complex cascade of chemical processes that results in LTP.
Cell signaling is a complex process where interactions between cells and their environment govern basic cellular functions and activities.
Dr. Jan Höpker, Dr. Silke Oeljeklaus, Prof. Dr. Nikolaus Pfanner, Dr. Sebastian Stiller, Prof. Dr. Bettina Warscheid, Prof. Dr. Nils Wiedemann and their team of researchers have demonstrated that this protein complex is essential for the integration of certain proteins into the inner membrane of mitochondria — proteins that play a role in cellular respiration and other processes.
«This camera has the potential to greatly enhance our understanding of very fast biological interactions and chemical processes that will allow us to build better models of complex, dynamical systems such as cellular respiration, or to help doctors better deliver and monitor light - based therapies,» says Richard Conroy, Ph.D., program director for Optical Imaging at NIBIB.
By systematically illustrating key cellular processes and multilayered circuit - host interactions, it further sheds light on quantitative biology towards a better understanding of complex bacterial physiology.
While the disease is caused by a single gene mutation, the manifestation of the disease at a molecular level is nevertheless highly complex and involves multiple cellular processes.
«While it is well - established that obesity generates cellular and molecular stress leading to abnormal functioning of many cellular processes, the mechanisms remain incompletely understood,» said senior author Gökhan S. Hotamisligil, chair of the Department of Genetics and Complex Diseases and the Sabri Ülker Center for Nutrient, Genetic, and Metabolic Research.
The PAF1 complex has many essential diverse roles in controlling cellular processes and organ development in the embryo.
Only from these results can the team deduce which conditions are crucial for the development of complex life and whether Earth is the ideal place for the necessary cellular processes.
«Head and neck cancer is complex and there are many mutations, but we can infer there is a convergence on a cellular process for which we previously did not have genetic evidence.
Basic research is essential to identify new treatments by analysing the cellular activity and chemical processes within regions of the brain that control those complex behaviours impaired in psychiatric disorders.
The isoforms of this histone play complex regulatory roles in several cellular processes — epigenetic regulation of gene expression, selective regulation of developmental genes, and telomere maintenance — that could contributed to tumor growth and progression if dysregulated.
The IncuCyte ® Live - Cell Analysis System continuously analyzes cell function and provides insights into the complex and dynamic cellular processes of immunology.
Others were unanticipated, including significant differences in expression levels among genes involved in fundamental cellular processes such as ribosomal biogenesis, transfer RNA processing, and Notch - signaling — part of a complex system of communication that governs basic cellular activities and coordinates cell actions.
Stalled transcription complexes don't just lend DNA repair processes a helping hand; they can also end up causing double - strand breaks by interfering with the cellular machinery that replicates DNA.
We have shown that the human condensin complex functions in global 3D genome reorganization during the important process of cellular senescence (Yokoyama et al..
Enhanced amyloidogenic processing of APP by the ß - site APP cleaving enzyme (BACE) and the γ - secretase complex and reduced clearance lead to increased intracellular levels of soluble oligomeric Aß, resulting in cellular dysfunction comprising e.g., synaptic failure, mitochondrial dysfunction, enhanced oxidative stress, neurotransmitter and neurotrophin depletion, inflammation, and apoptosis which is reflected in patients as clinical symptoms such as cognitive deficits [2, 3].
Such work yields unique mechanistic insight by directly illustrating the complex spatial - temporal dynamics of fundamental cellular processes such as mitosis, morphogenesis, polarization, embryonic development, membrane trafficking and cytoskeleton dynamics.
This cellular damage affects proteins and DNA replication, and inhibits repair through many complex processes, including telomere shortening in the DNA components.30 - 31
The cellular respiration process consists of a very complex series of chemical reactions, but the short summary of it is that it ultimately converts food energy (from carbohydrates, fats, and proteins) into ATP energy.
A complex chemical process within your cells, called cellular respiration, ultimately converts the energy stored in the foods you eat into a form that is optimized for use at the cellular level of your muscles.
The body's cellular inflammatory processes are complex and intricate — but you do not need to know all of the details to understand the basics.
For example, when biting into an apple, the body will immediately signal a complex sequence of messages and processes to break down the apple into energy and essential structural nutrients for cellular repair and replacement.
The pre-eminent curiosity that I retain regarding health practitioners is that specialists in nutrition on occasion appear to not possess the adequate level of biochemical grounding to explain the vital processes happening at the cellular level during fasting and through manipulation of eicosanoids (fatty acids), conversely from my personal experiences, experts in biochemistry don't apply their vast knowledge of these complex physiological systems to basic fundamentals of nutrition in a sensible, practical sense.