Systems biology aims to study
complex cellular systems by systematically stimulating them, monitoring cellular responses, formulating mathematical and computational models to understand the data, and proposing new experiments to refine these models.
Not exact matches
To help make ideas about energy more concrete, for example, the new unit will use a variety of analogies from more familiar physical
systems (e.g., combustion and charging a cellphone battery) to help students understand those same energy - releasing and energy - requiring chemical reactions and energy transfer when they occur in living organisms (e.g.,
cellular respiration, creating a charge across a membrane in mitochondria and nerve cells) where the reactions are more
complex and difficult to observe.
The fields within biology are further divided based on the scale at which organisms are studied and the methods used to study them: biochemistry examines the fundamental chemistry of life; molecular biology studies the
complex interactions of
systems of biological molecules;
cellular biology examines the basic building block of all life, the cell; physiology examines the physical and chemical functions of the tissues and organ
systems of an organism; and ecology examines how various organisms interrelate.
In the second article, Grégory Batt, head of the InBio unit and co-last author with Pascal Hersen (CNRS) of the Laboratoire Matière et systèmes
complexes (CNRS / Paris Diderot University), explains how they managed to place a
cellular system in an unstable configuration: «We designed a computer program which aims to force the cells to take binary decisions randomly.
«This camera has the potential to greatly enhance our understanding of very fast biological interactions and chemical processes that will allow us to build better models of
complex, dynamical
systems such as
cellular respiration, or to help doctors better deliver and monitor light - based therapies,» says Richard Conroy, Ph.D., program director for Optical Imaging at NIBIB.
The HFSP supports novel, innovative and interdisciplinary basic research focused on the
complex mechanisms of living organisms; topics range from molecular and
cellular approaches to
systems and cognitive neuroscience and the interactions between organisms.
The CCP is engaged in numerous multidisciplinary projects in other model
systems (e.g. fly, zebrafish, yeast) that aim to determine how
complex molecular circuits function and evolve in response to genetic and environmental changes,
cellular differentiation, evolution and disease.
Current in vitro hematopoiesis models fail to demonstrate the
cellular diversity and
complex functions of living bone marrow; hence, most translational studies relevant to the hematologic
system are conducted in live animals.
The team also found that DHODH binds a particular kind of lipid present in mitochondrial respiratory chain
complex, an important
system for
cellular energy production.
Finally, in a collaboration with Frank Jülicher's group at the Max Planck Institute for the Physics of
Complex Systems, we are using these data to develop physical models that will help us understand how local
cellular adhesive, elastic and contractile properties are influenced by PCP proteins and other molecules, and how they combine to produce specific packing geometries at a global level.
The IncuCyte ® Live - Cell Analysis
System continuously analyzes cell function and provides insights into the
complex and dynamic
cellular processes of immunology.
Others were unanticipated, including significant differences in expression levels among genes involved in fundamental
cellular processes such as ribosomal biogenesis, transfer RNA processing, and Notch - signaling — part of a
complex system of communication that governs basic
cellular activities and coordinates cell actions.
According to a release from Dr. Hassan Dihazi, editor in chief, the journal covers all areas of proteomics including basic proteomic research; structural, functional, property, and interaction analysis of
cellular systems, organelles, and protein
complexes; and protein expression profiling for the discovery and validation of diagnostic and prognostic disease biomarkers.
Specifically, Dangl and his team investigate how the plant immune
system discriminates between microbial friend and foe in a
complex environment, using tools and techniques from genomic, structural,
cellular, and molecular biology.
These interactions are typically plentiful during exercise, where continuous movement meets specific
complex coordinations throughout different
systems within the body, often generating on the
cellular level.
The
complex lymphatic
system acts as the body's drainage
system, a sewage
system for
cellular metabolic toxins, filtering and removing waste by products from the body.
The pre-eminent curiosity that I retain regarding health practitioners is that specialists in nutrition on occasion appear to not possess the adequate level of biochemical grounding to explain the vital processes happening at the
cellular level during fasting and through manipulation of eicosanoids (fatty acids), conversely from my personal experiences, experts in biochemistry don't apply their vast knowledge of these
complex physiological
systems to basic fundamentals of nutrition in a sensible, practical sense.
The HTML5 driven 3D Stress Simulator is a
complex, scientifically accurate exploration of how stress affects the body at the
systems, organ, and
cellular levels.
With respect to patent work, he has litigated and advised clients in a wide range of technologies, including
complex cellular communications technology, television technology, encryption
systems, GPS and other navigation
systems, automobile technology, internet provider
systems, printers and print heads, fiber optics, and electric razors, amongst others.