Sentences with phrase «complex diseases affecting»

In fact, Ostrander, who works at the NHGRI's Cancer Genetics and Comparative Genomics Branch, was one of the lead authors of a white paper arguing for support to sequence the dog genome at a level of quality already available at the time for the mouse, «to better understand the genetic basis of complex diseases affecting both human and dog.»

They studied these correlations in 65 complex diseases affecting almost every system in the body, including arthritis, depression and lung cancer, and in 95 Mendelian disease groups (representing 213 disorders).

Tufts Medical Center is a 415 - bed robust organization, providing everything from routine medical care to treating the most complex diseases affecting adults and children.

Not exact matches

She has had experiences with reporters who thought the scientific community «didn't know anything» when she expressed caveats and uncertainty around a complex topic (such as how mosquito - borne diseases in the U.S. - Mexico border region may be affected by climate change).

Standard approaches also struggle to find combinations of multiple genes that affect disease risk in complex ways (known as genetic interactions).

Today in Cell and associated journals, 24 research studies from the landmark BLUEPRINT project and IHEC consortia reveal how variation in blood cells» characteristics and numbers can affect a person's risk of developing complex diseases such as heart disease, and autoimmune diseases including rheumatoid arthritis, asthma, celiac disease and type 1 diabetes.

In the review, Amanda Forde, PhD, and Colin Hill, PhD, of the APC Microbiome Institute at University College Cork, in Ireland, note that phages have complex relationships with bacteria in the gut that could affect health and disease.

«The parts of the human genome linked to complex diseases such as heart disease, cancer and neurological disorders can often be far away from the genes they regulate, so it can be dificult to figure out which gene is being affected and ultimately causing the disease.»

«A pathological and very complex autoimmune reaction of the skin»: This is the definition doctors and scientists use to describe psoriasis, a disease that affects one to three percent of the population.

SLE is a genetically complex chronic relapsing autoimmune disease characterised by inflammation that may affect different tissues, including the skin, joint linings, lungs, kidneys and other organs.

«Crohn's disease is a complex disorder with multiple genes and environmental factors involved, which disproportionally affects individuals of Ashkenazi Jewish ancestry,» explained lead researcher Inga Peter, Professor of Genetics and Genomic Sciences at the Icahn School of Medicine at Mount Sinai in New York City.

Professor Samani concluded: «While we know about many lifestyle factors such as smoking that affect risk of coronary heart disease, our findings underscore the fact that the causes of this common disease are very complex and other things that we understand much more poorly have a significant impact.

Articles focus on topics including how healthy relationships early in life affect physical and mental health in childhood and beyond; the role of intimate relationships in coronary heart disease; the need to focus on partners when treating someone with chronic disease; and the increasingly complex biological pathways involved linking relationships to health.

CSIC researcher adds: «We have confirmed that mutation is found in both copies of the gene, one inherited from the father and the other one inherited from the mother, in the four women affected by the disease, causing an absolute absence of STAG3 protein and meiotic cohesin complex in these women.

«This study makes important observations about home life that may affect susceptibility to complex diseases later on in life.»

«This new study shows that complex I deficiency is, in fact, a global phenomenon in the brain of persons with Parkinson's disease, and is found indiscriminately in both affected and healthy brain regions.

To better understand this complex tissues and its functions — and the diseases that affect it — a multicenter team led by researchers at the Broad Institute of MIT and Harvard and Massachusetts General Hospital has released a census of the cells that make up the lining of the small intestine, using gene expression profiles of more than 53,000 individual cells from the mouse gut or gut organoid models.

However, the picture that emerges from studies in patients affected by brain disease and neurological conditions is more complex.

The findings add to our understanding of the factors influencing sex differences, and how that may affect complex diseases.

Genes and mechanisms involved in common complex diseases, such as the autoimmune disorders that affect approximately 5 % of the population, remain obscure.

«This is a very complex disease that can affect any organ,» says Dr. Rondelli.

A 2016 study by researchers from the Buck Institute for Research on Ageing and the UCLA Easton Laboratories for Neurodegenerative Disease Research, showed that memory loss in Alzheimer's patients can be reversed, and improvement sustained, using a complex, 36 - point therapeutic personalized program that involves comprehensive changes in diet, brain stimulation, exercise, optimization of sleep, specific pharmaceuticals and vitamins, and multiple additional steps that affect brain chemistry.

The onset of these diseases is affected by complex interactions of genetic and several environmental factors.

Structure is controlled by genes that affect bones, muscles, tendons, ligaments, and growth rate, and health depends on gene interaction as simple as that governing progressive retinal atrophy (the dog either has it or he doesn't; there's no halfway) or as complex as that influencing various autoimmune diseases, seizures, or various circulatory defects.

Elbow dysplasia is a complex, inherited disease which primarily affects intermediate and large breed dogs however this condition may be seen in any breed.

This complex of diseases can affect either the small or large intestine and can be managed with diet and with drugs in some cases.

Cancer is a complex disease that can affect multiple body systems.

Pododermatitis (inflammation of the feet) is a complex of diseases affecting the pads or interdigital haired skin.

Developmental patellar luxation is therefore no longer considered an isolated disease of the knee, but rather a consequence of a complex skeletal abnormalities affecting the overall alignment of the limb, including:

It is also known as Canine Infectious Respiratory Disease Complex (CIRDC) and Canine Infectious Tracheobronchitis as it affects the dog's lungs, windpipe and voice box.

If inheritance is complex, even more dogs might carry genes that could produce the disease if they happen to be mated with a dog that can «fill in the blanks» to produce affected pups.

Kennel cough is not a specific disease, but rather a complex of respiratory diseases affecting dogs,... Learn More

Heartworm disease is very complex and can affect many vital organs, including the heart, lungs, kidneys, and liver.

While it is known that this inflammatory condition is caused, in part, by a complex interplay between oral bacterial populations and the immune system of affected cats, the exact mechanism of the development of periodontal disease in cats remains elusive.

Chronic kidney disease (CKD) is a common, complex and progressive disease that is estimated to affect more than a third of cats over 10 years of age.

Smallholder and subsistence farmers, pastoralists and artisanal fisherfolk will suffer complex, localized impacts of climate change... [including] spread in prevalence of human diseases affecting agricultural labor supply.»

Addiction is a complex disease that affects every person that is involved.