Sentences with phrase «complex diseases such»

This is because canine behaviours are similar to complex diseases such as Hypothyroidism, where there are both environmental and multiple genetic components.

In my practice, I explore the genetic and environmental factors that influence wellness - from complex diseases such as cancer and Lyme Disease to chronic illnesses such as fatigue and Crohn's disease.

«The Knapps have applied their remarkable energy and resources — including hard work — to finding better ways to learn about complex diseases such as lupus and to use that knowledge to help others,» said James Madara, MD, dean of the biological sciences and the Pritzker School of Medicine and vice president for medical affairs.

Genome - wide association studies are a critical tool in the detection of genes involved in complex diseases such as diabetes and cancer or traits such as height and obesity.

«The parts of the human genome linked to complex diseases such as heart disease, cancer and neurological disorders can often be far away from the genes they regulate, so it can be dificult to figure out which gene is being affected and ultimately causing the disease.»

Today in Cell and associated journals, 24 research studies from the landmark BLUEPRINT project and IHEC consortia reveal how variation in blood cells» characteristics and numbers can affect a person's risk of developing complex diseases such as heart disease, and autoimmune diseases including rheumatoid arthritis, asthma, celiac disease and type 1 diabetes.

The advantages of MFCs may allow widespread use of diagnostic procedures that are currently too expensive to implement (e.g., prescreening for cancer) while the new capabilities may dramatically improve our ability to understand complex diseases such as cancer (e.g., through single - cell analysis).

Highlighting the collaboration, Hughes said, «This study demonstrates how the synergy between experimental and computational approaches can help unravel the nature of a complex disease such as HD.»

Patients with chronic and complex disease such as psoriasis now travel from far and wide to receive my treatment recommendations.

Not exact matches

She has had experiences with reporters who thought the scientific community «didn't know anything» when she expressed caveats and uncertainty around a complex topic (such as how mosquito - borne diseases in the U.S. - Mexico border region may be affected by climate change).

These basic principles can be applied to the study of more complex mental illnesses such as schizophrenia, bipolar disorder or Alzheimer's disease.

But noise has also been linked to health problems, such as heart disease and mental illness, and has been shown to change social behavior and interfere with the performance of complex tasks.

Scientists have shifted from studying single molecules to investigating large complexes of interacting biological macromolecules involved in processes such as metabolic pathways, gene expression, and development of disease.

To answer questions about complex neurological diseases such as Alzheimer's and multiple sclerosis, one needs biostatisticians, disease experts, clinical experts, high throughput genotyping capacity, databases and databanks, and «you need them at a level that you couldn't expect to find in one lab,» he says.

David Kessler, the former commissioner of the Food and Drug Administration, is calling for a big government - funded research project to help fill in the gaps in genetic pathways in people, which are turning out to be far more complex than expected for illnesses such as heart disease and which may be beyond the ability of private companies and smaller labs to figure out and pay for.

A team from the Spanish National Cancer Research Centre (CNIO) has determined for the first time the high - resolution structure of a complex (R2TP) involved in key processes for cell survival and in diseases such as cancer.

In the federal government's fiscal year 2006 (beginning 1 October 2005 through 30 September 2006), AHRQ plans to fill gaps in knowledge about patient care dealing with complex conditions, such as multiple diseases and risk factors.

We can view these advancements as opportunities for our global society to tackle complex problems, such as energy demands, food and water security, and disease.

A new center has opened at Purdue University to create software to help manage complex crises such as disease outbreaks and financial calamities.

Global complex problems, such as energy, environmental issues, pandemics or diseases related to aging societies, also have to be faced jointly by different disciplines.

And even if such a demand existed, there was no evidence that genetic counseling could help patients with psychiatric disorders, which — like most of the more common diseases — are caused by a complex interplay of multiple genes and variants as well as environmental factors.

The lead author, Dr Ryan West added: «We hope that this work helps to tease apart complex molecular processes occurring in neurons and identify how these can go wrong in neurodegenerative diseases, such as Frontotemporal Dementia.»

The research, made possible by the availability of high - resolution data in space and time on veterinarian movements in the study area, shed light on the actual significance of operator movements in disease spread, a still poorly understood topic due to the highly diverse and complex nature of such movements and to privacy issues in data collection.

The hope is the technique could be used to unpick the role of proteins in many complex processes, such as the consolidation of memories, or be used to block the interactions between proteins within cells to help illuminate the processes that underpin disease.

There has been increased interest in experimental, computational and theoretical research in this complex field due to exciting new potential applications in treating diseases, such as cancer.

«Computer modeling, also known as in silico modeling, of such a complex disease allows us to work toward potential treatments much more rapidly.»

MEGENA (for Multiscale Embedded Gene Co-expression Network Analysis) projects gene expression data onto a three dimensional sphere, allowing scientists to study hierarchical organization patterns in complex networks that are characteristic of diseases such as cancer, obesity, and Alzheimer's.

With their experimental collaborators, the researchers are now exploring whether the algorithm can model more complex biological processes, such as the dynamics of insulin secretion in the pancreas and its relationship to the onset of a disease like diabetes.

Allelic complexity in genes will be large, and such complexity will make the analysis of genotype - phenotype relationships difficult, particularly in the situation of common, complex diseases.

With the understanding that some diseases such as obesity are metabolic syndromes in which multiple biochemical pathways interact to cause complex symptoms, metabolic testing offers a way to gauge health over a lifetime.

Professor Samani concluded: «While we know about many lifestyle factors such as smoking that affect risk of coronary heart disease, our findings underscore the fact that the causes of this common disease are very complex and other things that we understand much more poorly have a significant impact.

In humans, the cerebellum's extensive connectivity with the rest of the brain suggests it does far more than learn motor skills: it has been shown to have a part in both perception and cognition, with recent work linking cerebellar dysfunction to such complex diseases as schizophrenia and autism.

The main types of complex wounds include those resulting from chronic disease such as diabetes or venous insufficiency, pressure ulcers and non-healing surgical wounds.

According to Halassa, the new research sets the stage for ever more detailed studies on the complex behavior involved in how the mammalian brain pays attention to what's important, and especially how those neural circuits are broken in cases of attention - deficit diseases, such as ADHD, autism, and schizophrenia.

Such disorders are caused by complex interactions among genes and environmental factors; the challenge facing researchers now is to find out which genes are involved and how they influence disease.

One is to identify disease genes — particularly those involved in conditions with complex origins, such as asthma and heart disease — by comparing genetic sequences within a group of patients with a given disease.

«The approach may be extended to additional complex disorders and diseases for which we don't understand the underlying biology but do have drugs that may have some beneficial actions, such as depression, anxiety, schizophrenia and others in need of more effective therapies.

Buckler is credited with improving association mapping, one of the methods used for this research, that is being used to understand the genetic basis of such complex traits as vitamin A content, drought tolerance, nitrogen use, carbon metabolism, disease resistance, and crop and milk yields.

Antibody microarrays are powerful tools for simultaneous detection of hundreds or thousands of blood - borne protein biomarkers at once, potentially allowing accurate fingerprinting and improved diagnostics of complex pathophysiological states such as cancers, neurodegenerative diseases and autoimmune conditions.

This multidisciplinary analysis provides the blueprint for a detailed understanding of complex biological processes, the pathogenic mechanisms leading to diseases such as cancer, autoimmune or genetic diseases.

[NEWS, 4 June 2013] Protein microarrays, representing more than one third of all human proteins, provide a unique possibility to study complex autoimmune diseases, such as multiple sclerosis (MS).

«deCODE's success in localizing disease - contributing genetic factors even in such complex disorders as anxiety and obesity marks once more achievements that we believe could not easily be obtained by anyone else,» notes Jonathan Knowles, Head of Global Research at Roche.

We regularly treat patients with complex conditions and those that are considered high - risk, such as the elderly, patients with co-existing diseases, hereditary disease such as Marfan syndrome, and people requiring re-operation to repair previous procedures.

Such genome - wide studies look for factors that influence genome function and disruptions that contribute to complex disease.

Blood tests are routine and simple ways to diagnose a number of medical conditions, but until recently, such simplicity hasn't applied to a complex disease like cancer.

Our understanding into the genetic underpinnings of such complex diseases as certain cancers, heart disease and diabetes, to name just a few, has grown by many orders of magnitude.

Their discovery — which involved the work of both neuroscientists and geneticists — underscores the importance of collaborative and cross-disciplinary research when dealing with complex neurodegenerative diseases such as ALS.

Systems biology is an approach to biomedical research in which scientists combine complex «omics» datasets to develop a more complete understanding of complex biological systems, such as the regulation of whole genome - level transcription, regulation of the 3D genome, the role of signaling and metabolic pathways in disease, and more.

By combining advanced approaches such as cell sorting and single cell analysis, researchers will gain a better understanding of the complex genetic landscape of disease.

Continued research may allow HPFM to be used as a probe so, for instance, it would be possible to study the effect of new treatments being developed to save plants such as citrus trees from bacterial diseases rapidly decimating the citrus industry, or study fundamental photonically - induced processes in complex systems such as in solar cell materials or opto - electronic devices.