Sentences with phrase «complex kinase activity»
The mechanism by which rapamycin inhibits mTOR - raptor complex kinase activity is not completely understood.
http://cancerres.aacrjournals.org/ Not exact matches
Disruption of Ca2 + - dependent cell - matrix adhesion enhances c - Src kinase activity, but causes dissociation of the c - Src / FAK complex and dephosphorylation of tyrosine - 577 of FAK in carcinoma cells.
Rapamycin forms an inhibitory complex with the FRB domain of mTOR and inhibits the kinase activities of mTOR protein (18, 19).
Through interaction with the cdk / cyclin complexes, p21waf1 / cip1 modulates their kinase activity, resulting in cell growth arrest (10).
Kapoor P, Bao Y, Xiao J, Luo J, Shen J, Persinger J, Peng G, Ranish J, Bartholomew B, Shen X. (2015) Regulation of Mec1 kinase activity by the SWI / SNF chromatin remodeling complex.
Kapoor P, Bao Y, Xiao J, Espejo A, Yang L, Bedford MT, Peng G, Shen X. (2015) Phosphorylation - Dependent Enhancement of Rad53 Kinase Activity through the INO80 Chromatin Remodeling Complex.
Structure of the BRAF: MEK Complex Reveals a Kinase Activity Independent Role for BRAF in MAPK Signaling