Sentences with phrase «complex role in cancer»
The new research, which studied the immortalization process using genome - engineered cells in culture and also tracked skin cells as they progressed from a mole into a malignant melanoma, suggests that telomerase plays a more complex role in cancer.
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The complex role of branched chain amino acids in diabetes and cancer.
More importantly, the fibronectin part of the complex is expressed during a cell's transition to cancer and plays a role in cell growth, migration and differentiation.
Imielinski is also building his own lab, which will focus on understanding the role of complex DNA rearrangements in cancer.
The proteasome complex is present in all multicellular organisms, and plays a critical role in cancer by allowing cancer cells to divide rapidly.
An increasing body of work shows that similarly complex aneuploidy variations play a role in some forms of cancer and we think that the rapid accumulation of NGS genomics data combined with novel in - silico techniques - like the ones developed in our study - will soon lead to a better understanding of the relationships between aneuploidy and allele selection».
This is why recent work in the field of cancer research has focused on picking apart the complex cellular pathways involved in the development of different cancers and identifying the roles of key proteins involved, with the goal of being able to discriminately and effectively eliminate cancerous cells from the body.
His research includes, uncovering the complex transcriptional network that exists in the tumor microenvironment roles of cancer initiating cells in immune suppresion, understanding the mechanism of T cell anergy and molecular analysis of T cell repertoire of patients with breast cancer.
«The integration of complex genomic data sets enabled us to discover an intricate array of genomic changes and validate one specific change that occurs in the vast majority of all ovarian cancers,» said lead author Paul T. Spellman, Ph.D., Lawrence Berkeley National Laboratory, Berkeley, Calif. «Significantly, we have also found new information regarding the role that the BRCA1 and BRCA2 genes play in determining survival.»
In addition, recent genome - wide association studies have identified several hundred common genetic variants — inherited changes in the DNA sequence of the human genome — that play a role in an individual's susceptibility to complex human illnesses such as heart disease, mental illnesses, cancer and diabeteIn addition, recent genome - wide association studies have identified several hundred common genetic variants — inherited changes in the DNA sequence of the human genome — that play a role in an individual's susceptibility to complex human illnesses such as heart disease, mental illnesses, cancer and diabetein the DNA sequence of the human genome — that play a role in an individual's susceptibility to complex human illnesses such as heart disease, mental illnesses, cancer and diabetein an individual's susceptibility to complex human illnesses such as heart disease, mental illnesses, cancer and diabetes.
Manzano, R. G., Martinez - Navarro, E. M., Forteza, J. & Brugarolas, A. Microarray phosphatome profiling of breast cancer patients unveils a complex phosphatase regulatory role of the MAPK and PI3K pathways in estrogen receptor - negative breast cancers.
The complex role of branched chain amino acids in diabetes and cancer.