Escherichia coli and many other bacteria produce cellulose as a
key component of the extracellular matrix that coats the cells to form a biofilm, a complex multicellular community consisting of numerous bacteria, exopolysaccharides (like cellulose), protein fibers, and DNA (4 — 6).
Their role in mediating adhesion to either
components of the extracellular matrix or to other cells is now well established.
Huntingtin null neurons exhibit a significant reduction in transcripts encoding proteins destined for the extracellular space, many of which are
components of the extracellular matrix or involved in cellular adhesion, receptor binding and hormone activity.
By contrast, Kunkemoeller's research focuses on TSP2,
a component of the extracellular matrix.
TSP2 is
a component of the extracellular matrix that influences how the matrix is formed, as well as the development and communication of other types of cells that grow within the matrix.
Jun. 6, 2013 —
A component of the extracellular matrix that surrounds cells plays a role in insulin resistance and may be a good therapeutic target.