Sentences with phrase «component of the immune system»

Most prior studies had not taken into account the involvement of other components of the immune system.
By revealing a novel but widespread cell signaling process, the scientists may have found a way to manipulate an important component of the immune system into more effectively fighting disease.
The other major component of the immune system is called the cell mediated immune system.
These are critical components of the immune system that help the body fight off viral and bacterial infections.
An important component of the immune system, antibodies are responsible for recognizing proteins in foreign cells and pathogens.
It is this stem section that doesn't change significantly from one antibody to another, and takes on the role of binding to other key components of the immune system to mount a defence against an invasive pathogen.
«While the newest therapies for rheumatoid arthritis have helped transform our ability to treat the disease, they are fairly blunt instruments — blocking components of the immune system in a non-specific, global way,» said first author Deepak Rao, who co-directs the Human Immunology Center at BWH.
«This applies particularly to immunotherapies, but many conventional therapies such as chemotherapy also rely on components of the immune system for their effectiveness.
Using gene - targeted mice and human cells that lack specific components of the immune system, a better understanding of the immune response to DENV and ZIKV is critical for developing much - needed vaccines and antivirals.
multiparametric analysis of each cell component of the immune system, either in normal conditions or exposed to pathogens, thanks to around 300 quantitative parameters
Hugh Brady of Imperial College London and colleagues found that mice lacking a gene called E4BP4 could make all other components of the immune system apart from natural killer cells, proving that the gene is indispensable for making the cells (Nature Immunology, DOI: 10.1038 / ni.1787).
To test this hypothesis, Arnold used an advanced molecular technique called RNA interference to silence core components of the immune system.
Now, researchers can use this new database to see how a change in FCGR2 or another gene affects components of the immune system and, subsequently, incorporate this information in the design of future studies.
Still, the large majority of approved immunotherapies aims at weakening or blocking pro-inflammatory components of the immune system.
«This implies that IL - 37 may be a basic component of immune system regulation, with IL - 37 levels affecting many other pieces of the overall response,» Fujita says.
To better understand how these normally helpful components of the immune system are put to nefarious tasks in cancer cells, Verma and his colleagues developed a new method of inducing non-small-cell lung cancer in mice.
By revealing a novel but widespread cell signaling process, the Sauer lab may have found a way to manipulate an important component of the immune system into more effectively fighting disease.
This fluid may contains cellular debris, toxins, cancer cells, bacteria, and viruses, as it flows to filters, called lymph nodes, which are central components of the immune system.
Your liver is a critical component of your immune system because it detoxifies your body.
Inflammation is a natural component of the immune system and can help fight a wide variety of bodily insults, ranging from infections to a whack by a hammer.
Researchers have discovered that if t - cells are removed (an important component of immune system function) from the dog and then returned to the dog after chemotherapy, the t - cells help to fight the B - cell lymphoma.
Li Gan, PhD, and her team showed that targeting key components of the immune system could be a new therapeutic strategy for a common form of dementia.
Normally during HIV infection, a restriction factor called APOBEC3G acts as a molecular roadblock, preventing the virus from reaching its target — the CD4 T white blood cells that are a major component of the immune system.
They looked specifically for genes coding the major histocompatibility complex (MHC)-- a molecule found on the surface of cells that acts as a crucial component of the immune systems of most vertebrates.
Lymphocytes, a special type of white blood cell, are essential components of the immune system.
Molecular microbiologists from the Keck School of Medicine of USC have discovered that mice lacking a specific component of the immune system are completely resistant to sepsis, a potentially fatal complication of infection.
Phenotyping of every cell component of the immune system either in normal conditions or exposed to pathogens, thanks to around 300 quantitative parameters.
Immunology is the study of components of the immune system and their function.
Other research groups previously reported that the M1 protein contributes to strep virulence because it makes it harder for immune cells to engulf the bacteria, or bind and inhibit other components of the immune system, such as antibodies.
Cytokines orchestrate other components of the immune system to appropriately fight the invading virus, while chemokines direct these components to the location of infection.
Even if one or two + aspects of it are not present or working correctly the vast majority of humans do still have a component of their immune system that is «natural».
Not being breastfed can disrupt optimal growth and development, especially in the first two years, when the key components of the immune system are forming to protect the child for life from chronic illnesses such as diabetes, cancer, and autoimmune diseases.
* CD4 cells are a component of the immune system attacked by HIV.
The scientists drew inspiration from built - in components of the human body's innate defenses called antimicrobial peptides, which act in concert with other components of the immune system to help prevent infections.
For the study, the researchers created a line of zebrafish with defective immune systems by inserting a mutation into a gene required for development of an important component of the immune system.
Lymphoma in animals is a malignant cancer originating from lymphocytes, which are an important component of the immune system.
Victor was doing basic research on a component of the immune system called the complement system, but later he joined Ruth in her work on malaria vaccine.
This study delivered the drug via a local injection to avoid any potential systemic effects from inhibiting a component of the immune system.
The reaction begins when an antibody activates a component of the immune system known as a mast cell, which then blasts out a barrage of chemicals.
This process depends on regulatory T - cells, a component of the immune system that acts as a «brake» for other immune cells.
Kipnis and his team first suspected a link between the immune system and social behavior when they found that mice lacking T cells, key components of the immune system, show little interest in their peers.
His team did not set out to study beverages — «We're immunologists, not tea researchers,» Bukowski says — but rather the actions of gamma delta T cells, long known as a key component of the immune system.
There were higher levels of three types of white blood cells that are key components of the immune system: leukocytes, monocytes and natural killer cells.
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