Sentences with phrase «compounds on cancer»

Other publications on cancer chemoprevention include Comprehensive review of cancer chemopreventive agents evaluated in experimental carcinogenesis models and clinical trials, Chemopreventive effects of natural dietary compounds on cancer development, Organosulfur compounds in cancer chemoprevention, Cancer prevention by natural compounds, Cruciferous vegetables and cancer prevention, Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis, Cruciferous vegetables: cancer protective mechanisms of glucosinolate hydrolysis products and selenium.

Their method, called PRISM, uses a molecular barcoding system to test potential drug compounds on cancer and other cell lines at an unprecedented scale and speed.

Review: Impact of dietary compounds on cancer - related gut microbiota and microRNA — Muhammad Shahid Riaz Rajoka — Applied Microbiology and Biotechnology

Not exact matches

Read this AWESOME article on new research that shows a compound in plants called apigenin could stop breast cancer cells from becoming resistant to cell death.

We may consider stopping breastfeeding only if a mother has cancer, or is so seriously ill that it is physically impossible for her to breastfeed; if she is on treatment with radioactive compounds or is receiving anti-cancer drugs.

The drug - like compounds can be modified and developed into medicines that target a protein in the human body that is responsible for chemotherapy resistance in cancers, said biochemist Pia D. Vogel, lead author on the scientific paper reporting the discovery.

In the early 1990s, in vitro tests on cancer cells by Lane and his colleagues hinted that some compounds could restore mutant p53's normal function.

«Our computer aided drug screening process has now identified two new classes of anti-cancer agents, specifically targeting two distinct and novel mechanisms underpinning cancer,» said Dr Andrea Brancale from Cardiff University's School of Pharmacy, who led on the compound's design.

They have also isolated specific receptors on the surfaces of cancer cells that green tea compounds may interact with.

Hyder and his research team have focused on luteolin, a naturally occurring, non-toxic plant compound that has been proven effective against several types of cancer.

As an example, he cited his previous research on baked purple potatoes that have compounds that help suppress chronic intestinal inflammation elevated from a high - calorie diet and stem cell proliferation, which are linked to both colitis and colon cancer.

The researchers, who reported their findings in a recent issue of BMC Complementary and Alternative Medicine, suggest that the findings could pave the way for clinical testing of the compounds on human colon cancer, which is the second most common cancer in women and the third in men.

Compounds based on RK - 33, he says, might have value in treating a broad array of cancers that highly express DDX33 or as a supplement to radiation, making conventional doses more effective or improving the killing ability of lower doses.

Choi's team wanted to see what effect the two compounds have on breast cancer cells.

«After screening a natural compound library, we developed an unbiased look at combinations of nutrients that have a better effect on prostate cancer than existing drugs,» says corresponding author Stefano Tiziani, assistant professor in the Department of Nutritional Sciences and Dell Pediatric Research Institute at UT Austin.

U.S. officials in Milwaukee have arrested a cancer researcher from China, Huajun Zhao, 42, on charges of «economic espionage» after a colleague at the Medical College of Wisconsin (MCOW) reported that vials of a research compound were missing.

The compound, which is widely prescribed for breast cancer, is known to block oestrogen receptors on many cancer cells, so inhibiting their growth.

«The main sources of these compounds include tea and citrus fruits and juices, which are readily incorporated into the diet, suggesting that simple changes in food intake could have an impact on reducing ovarian cancer risk.

«This paper reveals a metabolic frailty in cancer cells that is based on their own production of oxidizing agents that allows us to utilize existing redox active compounds, like vitamin C, to sensitize cancer cells to radiation and chemotherapy,» says co-author Garry Buettner, who was one of the first to propose that cancer cells might have a vulnerability to redox active compounds over 40 years ago.

«This is a significant example of how knowing details of potential mechanisms and the basic science of redox active compounds in cancer versus normal cells can be leveraged clinically in cancer therapy,» says co-senior author Douglas Spitz, who focused on the biochemical studies.

While thousands of agents based on camptothecin have been synthesized, and two of these analogs — irinotecan and topotecan — have been approved for treatment of many solid - tumor cancers, these compounds typically are highly toxic to healthy cells, and not all of them have proven effective as anticancer agents.

While past attempts to treat melanoma failed to meet expectations, an international team of researchers are hopeful that a compound they tested on both mice and on human cells in a petri dish takes a positive step toward creating a drug that can kill melanoma cancer cells without harming nearby healthy cells.

Examination of Drug Compound on Common Cancer Mutation Drug Discovery & Development (online)-- October 3, 2016

People continue to inhale cancer causing compounds directly into their lungs despite the overwhelming scientific evidence that smoking may harm then and / or their progeny & others on planet earth.

By understanding the context of a cell, we may identify compounds that work selectively on different cancers.

With Hutch staff scientist Dr. John Lamb, Simon recently identified a compound that may improve on drugs that treat ovarian and other cancers.

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Dr Behren said the «paradox breaking» compounds were tested on BRAF melanoma cells for their potential to inhibit their growth and, after being seen to successfully target these cells, were then tested for their growth - promoting effects on various colorectal cancer cells in comparison to the classical drugs.

Additionally, the compound they have developed allows them to profile other cancer types and see if they are dependent on BFL - 1 for their survival.

Historically, a potential therapeutic compound would be tested on cancer cell lines to validate the functional efficacy of the compound.

Pfizer initiated a Phase 1 clinical study for EOS200271 (NCT02764151) as a single agent in patients with malignant gliomas (brain cancer), an area of significant unmet need, based on brain penetration of the compound.

Number of proteins involved in a particular cancer, as well as drugs and compounds acting on cancer - related and their first neighbour proteins.

The N.I.H. has classified 54 compounds as known human carcinogens based on studies indicating they cause at least one type of cancer in people.

The cancer promoting effects of estrogen on breast tissue are restricted by lignan compounds which bind to estrogen receptors.

Even thought the USA Rice Federation doesn't agree with these concerns since according to them inorganic arsenic is considered a natural compounds, the Consumer Reports study disagrees, saying that inorganic arsenic as the form in which arsenic is found in the majority of products they analyzed is ranked by IARC (International Agency for Research on Cancer) among the top 100 Group 1 carcinogen substances.

The research says that concern over cancer causing compounds such as heterocyclic amines (HCAs), and polycyclic aromatic hydrocarbons), would be better directed toward educating consumers on the charring and blackening that occurs when grilling or barbecuing muscle meats, rather than cooking the meat in microwave ovens.

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Read this AWESOME article on new research that shows a compound in plants called apigenin could stop breast cancer cells from becoming resistant to cell death.

- Eating broccoli on the day you buy it to preserve its natural sugars and cancer - fighting compounds...

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While further research is needed to confirm the effects on human breast cancer, eating a primarily plant - based diet will deliver these potentially cancer - weakening compounds.

The chemical compound has been dosed in human PPAR for a number of years and has only provided positive results on cancer treatments, liver function, and metabolic efficiency.

Another one of natures super foods, broccoli is not only high in vitamin A but also contains a compound that has the ability to work on a genetic level to «switch off» cancer genes, AND to hinder the progression of cancer.

In addition, flax contains cancer - fighting compounds, called lignans, that can block the negative effects of excess estrogen on cells.

A tissue culture study of human breast - cancer cells found that epigallocatechin gallate, or EGCG, an active compound in green tea, protects against some forms of breast cancer by regulating estrogen receptors on breast cells and inhibiting growth and reproduction of estrogen - dependant breast - cancer cells.

Also, a 2012 study published on the Medical Journal 3 Biotech shows that the anti-cancer compounds in mushrooms play a crucial role as a reactive oxygen species inducer, mitotic kinase inhibitor, antimitotic, angiogenesis inhibitor, topoisomerase inhibitor all leading to apoptosis (cell death) and eventually checking cancer cell proliferation (4).

They help to digest your food, train your immune system to distinguish between friend & foe, turn your genes on and off, synthesize important vitamins that your body can't make on its own, aid in detoxification, neutralize cancer - causing compounds, and a host of other things.

By the way, in the NaturalHealth365 «Special Report» on whey protein, you'll discover the compounds in whey protein which are able to reduce muscle wasting related to aging, inhibit cancer cell growth, reduce the risk of diabetes and helps to combat cognitive decline associated with aging.

Based on these observations, DF's and substances that are part of the fibre complex such as antioxidants, flavonoids, sulphur containing compounds and folate have been proposed as potentially protective agents against colon cancer.

The phenolic compounds and antioxidants found in walnuts recorded a control on human cancer cells, according to the research conducted in 2010 by the University of Portugal.