Sentences with phrase «computational approaches for»

Computational approaches for variant prioritization include machine learning methods utilizing a large number of features, including molecular information, interaction networks, or phenotypes.

Bolton combined these human hearing models with model checking (an automated, computational approach for finding problems in complex systems) to assess masking in a common patient - monitoring device with six different alarms.

The team also developed a computational approach for analyzing patient - specific data to help doctors choose the most effective drugs for individual patients.

Results: Scientists at Pacific Northwest National Laboratory have developed a new computational approach for comparing receptor networks in cells.

Here, I discuss a novel computational approach for the detection of allostery in protein complexes by way of molecular dynamics simulation and advanced data reduction protocols.

In this talk I will describe a proposed computational approach for the identification and characterization of GPIs in LC - MS / MS datasets.

Not exact matches

We differentiated between computational approaches (either based on volume data, such as the number of mentions related to a party or candidate or the occurrence of particular hashtags; or endorsement data, such as the number of Twitter followers, Facebook friends or the number of «likes» received on Facebook walls), sentiment analysis approaches, that pay attention to the language and try to attach a qualitative meaning to the comments (posts, tweets) published by social media users employing automated tools for sentiment analysis (i.e., via natural language processing models or the employment of pre-defined ontological dictionaries), and finally what we call supervised and aggregated sentiment analysis (SASA), that is, techniques that exploit the human codification in their process and focus on the estimation of the aggregated distribution of the opinions, rather than on individual classification of each single text (Ceron et al. 2016).

Another target for the computational approach are flow batteries, in which the storage material is all dissolved in solution, allowing for a particularly wide range of elemental mixes.

Computers Aid Drug Design and Discovery The Carolina Center for Genome Sciences, as Vidha Iyer explains, illustrates how the synergy between experimental and computational approaches to drug design can significantly advance the discovery process.

Approaching the problem of the mind from a computer science perspective, Baum argues for a computational explanation of though — one that sees the mind as «a complex but compact program.»

Last week, at the Association for Computational Linguistics» Conference on Empirical Methods on Natural Language Processing, researchers from MIT's Computer Science and Artificial Intelligence Laboratory won a best - paper award for a new approach to information extraction that turns conventional machine learning on its head.

And the new approach for computing the absorption spectrum will be incorporated in an upcoming release of the widely used NWChem computational chemistry software suite later this year.

The development of a powerful new computational approach will now allow for a more comprehensive assessment of what people find aesthetically pleasing.

«We hope that by using these computational approaches to understanding cancer cell systems, we've widened the field for finding the new desperately needed cancer drugs,» said Dr Módos.

«The computational approach allows us to model, right down to the atomic level, how small changes in protein sequence can have a major impact on signaling,» said MacDermaid, assistant professor of research at Temple's Institute for Computational Moleccomputational approach allows us to model, right down to the atomic level, how small changes in protein sequence can have a major impact on signaling,» said MacDermaid, assistant professor of research at Temple's Institute for Computational MolecComputational Molecular Science.

Prof. Scharf says, «Our approach is both safe and inexpensive, and a much more appealing alternative for generating a complete shape at a low - computational cost, using an innovative data collection method.»

The team's approach is both safe and inexpensive, and a much more appealing alternative for generating a complete shape at a low - computational cost using an innovative data collection method.

Her team integrates both computational and experimental approaches to explore how perturbations to these gene networks can alter morphology, both within a species and across the grasses, with the ultimate goal of defining targets for improving grain yield in cereals.

But the study, conducted through the new USTAR Center for Genetic Discovery at the U of U, shows that Phevor's unique approach allows it to identify disease - causing genes more precisely than other computational tools.

«We normally approach genetics by limiting the investigation to single organisms or domains of life,» says Emmanuel Gonzalez, lead author of the study and bioinformatics specialist at the Canadian Centre for Computational Genomics at McGill.

The authors conclude that «the purely computational approach may therefore be able to narrow down the number of experiments needed for the development of new materials.»

A multidisciplinary team of scientists from K4DD partners Merck KGaA (Darmstadt), Heidelberg Institute for Theoretical Studies (HITS), and the Instituto de Biologia Experimental e Tecnológica (iBET)(Lisbon), applied state - of - the - art experimental and computational approaches to investigate the determinants of target residence times for a set of inhibitors of a widely studied cancer target, heat shock protein 90 (HSP90).

The researchers suggest, that although grammar as a whole might not be a better tool for examining language change, a more nuanced approach that combined computational methods with large - scale databases of both grammar and lexicon could allow for a look into the deeper past.

Now a team of scientists at the University of California, Irvine, has used a new computational approach — the «linkage disequilibrium decay» test — to search for signs of selection over the entire human genome.

It is anticipated that the computational approach developed in this study can also provide important insights on the role of magma degassing as a potential trigger for volcanic eruptions.

Their approach allows researchers to search for complex interactions by decoupling the order, or size, of interactions from the computational cost of identification.

The materials community is interested in using the team's tool as part of an integrated computational materials engineering approach to design structural components — which could help optimize materials properties and reduce uncertainty for given applications.

To bring all these data together for analyses, we leverage recently developed, dedicated computational approaches [27].

«Analysis of metastatic prostate cancers suggests treatment options: Study maps out abnormal signaling pathways in prostate cancer cells and provides computational approaches to identify individualized targets for therapy.»

Using high - powered computational tools and techniques and advanced bioinformatics expertise, the personalized medicine approach will enable researchers and physicians to predict and even prevent many health issues, and to better prescribe the right therapy for the right person at the right time.

We also want to make it easy for computational researchers to develop and share new analysis approaches.

This Ideas Challenge recognizes the need for an interdisciplinary approach to microbiome research and invites the scientific community — including microbiologists, ecologists, chemists, physicists, engineers, material scientists, nanoscientists, computational scientists and others — to submit their ideas for novel experimental tools and methods aimed at understanding microbial interactions and function from new perspectives.

Encourages applications for developing and testing innovative theories and computational, mathematical, or engineering approaches to deepen understanding of complex social behavior.

What's Next: This study also highlights the large number of spectra for which peptide and protein identifications are not achieved, opening the door for use of experimental and computational approaches to identify the significant numbers of peptides effectively ignored by proteomics studies to date.

According to Sushko, their new computational approach creates «a new paradigm in knowledge - based synthesis of highly ordered three - dimensional crystal structures» for a range of practical applications in catalysis and energy - storage technologies.

For the computational structure approach, they relied on molecular replacement software implemented by SBGrid, generating a shell script to iteratively run hundreds of searches.

The study demonstrated the advantages of having an integrated approach to gene prediction and developed a computational framework for combining multiple genome annotations.

For a systems - level understanding of all crucial protein interactions during cell division, we are combining automated single molecule calibrated imaging and computational data analysis with advanced machine learning and modelling approaches to build an integrated protein atlas of the human dividing cell.

Challenges to this approach include the need for innovation in machine learning algorithms and balancing the computational cost of high - resolution simulations with the value of the information they provide.

The Functional Genomic and Computational Assessment of Threats (Fun GCAT) program challenges research teams to develop new approaches for screening genetic information for evidence of a potential biological threat.

In one of the latest examples, a team led by Kenichiro Itami of Nagoya University and Djamaladdin G. Musaev of Emory University has used a computational - experimental approach to create a predictive regioselective reaction for C — H imidation of aromatic compounds (Chem.

The Graduate Certificate Program in Neural Computation and Engineering provides interdisciplinary training for students engaged in quantitative, mathematical, engineering and computational approaches to problems in neuroscience.

Ongoing: Posters Open for Viewing, Exhibit Hall, South Building Topics: Bioinformatics and Computational Approaches, Posters 1181 - 1457; Molecular and Cytogenetic Diagnostics, Posters 2370 - 2601

Application of Modern Toxicology Approaches for Predicting Acute Toxicity for Chemical Defense reviews the current state of computational and high - throughput approaches for predicting acute toxicity caused by chemical exposures likely to be encountered by deployed military Approaches for Predicting Acute Toxicity for Chemical Defense reviews the current state of computational and high - throughput approaches for predicting acute toxicity caused by chemical exposures likely to be encountered by deployed military approaches for predicting acute toxicity caused by chemical exposures likely to be encountered by deployed military personnel.

These data identify genes that are essential for colorectal cancer cell survival as well as synthetic lethal treatment combinations using novel computational approaches.

In the last decade we have witnessed tremendous advances in our understanding of the landscape of the molecular alterations that underpin many of the most prevalent cancers, in the use of automated high - throughput platforms for high - throughput drug screens in cancer cells, in the creation of more clinically relevant cancer cell models, and lastly in the development of more useful computational approaches in the pursuit of biomarkers of drug response.

To study such effects, the Comparative Genomics group employs computational and evolutionary approaches to analyze whole genome datasets for predicting genomic, epigenetic and expression differences between individuals.

Crucial for our success is the experimental validation of our computational approaches which we pursue in our laboratory or in collaboration with other scientists.

The EcoMOD (Model / Modify, Observe, Design) project will build on and extend our prior EcoMUVE curriculum for middle school, using a design - based research approach to combine an immersive virtual environment with hands - on interactive modeling through a scaffolded computational interface.

Examples may include systems science approaches (e.g., computational modeling and simulation, network analysis, and engineering control methods) to conceptualize prevention at the micro - or macro-levels of analyses; alternative intervention designs for when randomization is not possible; new methods for optimization of interventions; adaptive interventions and SMART designs; and innovative analytic approaches including time varying effect models, and models for incorporating intensive longitudinal data and / or real time data capture in prevention science research.