A big
concern about gene patents is that they hinder genetic research — once one company has patented a gene, other researchers may fear infringing on that patent by conduct further research on it, the argument goes.
That case virtually stopped gene therapy research and spawned widespread safety
concerns about gene therapy involving the liver.
Not exact matches
This Wolbachia approach is promising because it doesn't require genetically engineering or modifying the bugs — a strategy that has triggered opposition from people
concerned about releasing modified
genes into the wild.
But the advent of such revolutionary technologies, as well as others such as CRISPR - Cas9 and
gene - editing, have raised
concerns about a brave new world where «designer babies» are a possibility.
@DOC in addition to what we know
about immunology in animals and humans, what you described
concerning bacteria is precisely the definition of adaptation and not evolution, the
gene already exists!
«in addition to what we know
about immunology in animals and humans, what you described
concerning bacteria is precisely the definition of adaptation and not evolution, the
gene already exists!
This
concern about artificially transferring
genes between kingdoms and species in a way that has never occurred naturally is now being validated by a large body of science.
Former Alabama coach
Gene Stallings had some general complaints
about the committee that seemed to include Rice, noting his
concern for the qualifications for some proposed members.
But he is far more
concerned about the potential for accidental release of
gene - drive organisms by scientists, he says.
«Americans worried
about using
gene editing, brain chip implants and synthetic blood: US adults show more
concern than enthusiasm for using these to «enhance» human abilities.»
Concerning your story «A wrinkle pill that feeds your
genes» (24 September, p 10), never mind the wrinkles, what
about...
But
concern lingers
about how the HapMap will perform in the hunt for disease
genes.
A controversial paper
about modifying
genes in fertilized human eggs raised some serious ethical
concerns.
The discoveries of these proteins and
genes have the potential to address a wide range of critical agricultural problems in the future, including the limited availability of water for crops, the need to increase water use efficiency in lawns as well as crops and
concerns among farmers
about the impact heat stress will have in their crops as global temperatures and CO2 levels continue to rise.
A major
concern about genetically modified (GM) crops is that they might spread their
genes to nearby weeds or organic crops.
Some on the panel suggested they were particularly sensitive
about such
concerns given that it was at UPenn in 1999 that a young man, Jessie Gelsinger, died in a
gene therapy trial, setting the field back for years.
Discovering what mutations mean Researchers
concerned about patent infringement may abandon research on mutations within patented
genes, hindering progress to understand all of a mutation's effects.
Concerns have been raised
about the safety of
gene therapy in the past, not least
about links between the viruses used to transfer the
genes and disease.
Scientists who attended a meeting in Napa, California, in January to discuss potential uses of germline
gene - editing have written a perspective paper
about their
concerns for publication in Science.
He is also
concerned about China, which prohibits
gene - editing of embryos but does not strictly enforce similar rules, as shown by failed attempts to curb the use of ultrasound for sex selection and to stamp out unauthorized stem - cell clinics.
Adam, a robot designed at Aberystwyth University in the UK, created 20 hypotheses
about yeast
genes and illuminated a decades - old puzzle
concerning which
genes code for an enzyme.
Harris cited other examples of
concern — a review of 100 studies in the field of psychology in which the findings in only
about a third of the studies were reproducible; an effort by scientists at Bayer, another large drug company, that managed to reproduce the findings of only one - quarter of the studies under review; a just - published review of 25 historical candidate
genes for schizophrenia which found no evidence that the candidate
genes are more associated with the disease than other
genes.
We are
concerned that a public outcry
about such an ethical breach could hinder a promising area of therapeutic development,» write Lanphier and his colleagues, who include Fyodor Urnov, a pioneer in
gene - editing techniques and scientist at Sangamo BioSciences in Richmond, California.
«There are safety and environmental
concerns about releasing an organism that has a
gene drive into the wild,» Ossorio says.
They also say they are
concerned about the antibiotic resistance marker
gene that the wheat contains, and assert that the researchers «are openly releasing a synthetic version of a compound that... has had no long - term health safety tests whatsoever for human consumption, or for its impacts on non-target species.»
Nonetheless, the result has renewed
concern about the oversight of clinical trials for
gene therapy.
Next Wave asked: If research on
gene vectors can be used not only to further
gene therapy but also — potentially — to aid in the development of biological weapons, should scientists be
concerned about the potential applications of their research in genetics (as Joseph Rotblat suggested in a 19 Nov 1999 editorial in Science magazine?)
Gene drive research also raises regulatory
concerns about biosafety, biosecurity, and the potential for this technology intended for human benefit to be intentionally misused for harmful purposes.
This
concern was also brought to the forefront of the scientific and public consciousness when a report by Chinese scientists described the use of CRISPR - Cas to modify a
gene in human embryos making them resistant to HIV infection [to learn more
about CRISPR - Cas, read our previous blog].
Concerns about immunological consequences of rAAV - mediated
gene transfer were substantiated by the outcome of a clinical trial in which human hemophilia B patients were infused into the liver with rAAV -2-F.
Approve of stem cell research, transgenic animal research and human
gene therapy, although strict laws are needed to alleviate
concern about ethical issues
There is some
concern about using CRISPR - Cas9 as a therapy, because while it could delete the damaged portion from the HD
gene, it could also permanently remove a part of the healthy copy.
The genomes of bacteriodes and enterococcus reinforce something scientists have been
concerned about for years: the remarkable fluidity of the bacterial
gene pool.
The
concern is that people, armed with raw data
about their
genes but lacking a full understanding of what that data means for them on a practical level, could experience stress or seek unnecessary treatment.
You've probably read
about concerns over «designer babies,» whose DNA is shaped by
gene editing.
Lysogene's MPS IIIA
gene therapy clinical trial strategy includes a partnership with the MPS patient networks to ensure families are well informed
about our development program and are able to make informed choices
concerning the best treatment strategy for their children.
Some of the
concerns raised
about somatic
gene transfer are related to the possibility that it could inadvertently lead to germline
gene transfer.
The impressive / shameful statistics were gathered by Jemima Harrison, who prepared the BBC documentary Pedigree Dogs Exposed, and who says — though we joke somewhat
about Yogi» s rampant sex life — they should raise serious
concerns about his growing
gene pool dominance.
And even if that had been successful, there were
concerns about the species» longevity due to inbreeding, and a narrowing
gene pool.