Excitingly, our study points out that
condensin plays an important role in cellular senescence, a major tumor suppression mechanism.
Not exact matches
For many years, it has been clear that a protein complex called «
condensin»
plays a key role, but until now, biologists were divided on exactly how.
We found that the interaction between two classic factors,
condensin and TBP,
plays a pivotal role in 3D chromosome organization, and ensures that a critical set of genes, the actively transcribed housekeeping genes, are accurately segregated during mitosis (Figure B and C).