Sentences with phrase «conditions needed for changing»

«The work provides another important role for lymphocyte proliferation, to set up the conditions needed for changing function,» Biron said.

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

But if climate change isn't stabilized soon, the authors wrote,» [t] he large - scale loss of functionally diverse corals is a harbinger of further radical shifts in the condition and dynamics of all ecosystems, reinforcing the need for risk assessment of ecosystem collapse.»

These risks and uncertainties include competition and other economic conditions including fragmentation of the media landscape and competition from other media alternatives; changes in advertising demand, circulation levels and audience shares; the Company's ability to develop and grow its online businesses; the Company's reliance on revenue from printing and distributing third - party publications; changes in newsprint prices; macroeconomic trends and conditions; the Company's ability to adapt to technological changes; the Company's ability to realize benefits or synergies from acquisitions or divestitures or to operate its businesses effectively following acquisitions or divestitures; the Company's success in implementing expense mitigation efforts; the Company's reliance on third - party vendors for various services; adverse results from litigation, governmental investigations or tax - related proceedings or audits; the Company's ability to attract and retain employees; the Company's ability to satisfy pension and other postretirement employee benefit obligations; changes in accounting standards; the effect of labor strikes, lockouts and labor negotiations; regulatory and judicial rulings; the Company's indebtedness and ability to comply with debt covenants applicable to its debt facilities; the Company's ability to satisfy future capital and liquidity requirements; the Company's ability to access the credit and capital markets at the times and in the amounts needed and on acceptable terms; and other events beyond the Company's control that may result in unexpected adverse operating results.

For most long - term investors, there is no need to deviate from a solid investment plan just because you are concerned that market conditions might change.

[16:00] Pain + reflection = progress [16:30] Creating a meritocracy to draw the best out of everybody [18:30] How to raise your probability of being right [18:50] Why we are conditioned to need to be right [19:30] The neuroscience factor [19:50] The habitual and environmental factor [20:20] How to get to the other side [21:20] Great collective decision - making [21:50] The 5 things you need to be successful [21:55] Create audacious goals [22:15] Why you need problems [22:25] Diagnose the problems to determine the root causes [22:50] Determine the design for what you will do about the root causes [23:00] Decide to work with people who are strong where you are weak [23:15] Push through to results [23:20] The loop of success [24:15] Ray's new instinctual approach to failure [24:40] Tony's ritual after every event [25:30] The review that changed Ray's outlook on leadership [27:30] Creating new policies based on fairness and truth [28:00] What people are missing about Ray's culture [29:30] Creating meaningful work and meaningful relationships [30:15] The importance of radical honesty [30:50] Thoughtful disagreement [32:10] Why it was the relationships that changed Ray's life [33:10] Ray's biggest weakness and how he overcame it [34:30] The jungle metaphor [36:00] The dot collector — deciding what to listen to [40:15] The wanting of meritocratic decision - making [41:40] How to see bubbles and busts [42:40] Productivity [43:00] Where we are in the cycle [43:40] What the Fed will do [44:05] We are late in the long - term debt cycle [44:30] Long - term debt is going to be squeezing us [45:00] We have 2 economies [45:30] This year is very similar to 1937 [46:10] The top tenth of the top 1 % of wealth = bottom 90 % combined [46:25] How this creates populism [47:00] The economy for the bottom 60 % isn't growing [48:20] If you look at averages, the country is in a bind [49:10] What are the overarching principles that bind us together?

The signs of capital concentration tell us we need to start thinking about how we will execute a plan for the ultimate descent at perhaps a very crowded Hillary Step juncture somewhere in the future when shorter term weather conditions on the financial market mountain change.

It is well for us that he did so, for not only did he give us what we need most, but with radically changed social conditions the applications must change from age to age while his insights are eternal.

Under modern conditions, with changes occurring so rapidly that most specific occupational preparation becomes quickly out of date, it even appears that a fundamental liberal education is the best vocational education, for it develops the powers of imagination needed to meet new situations and the understanding of interrelationships required by life in an increasingly interdependent civilization.

There is also less attention to the historically - conditioned character of all formulations and therefore to the need for change in new historical circumstances.

As the changing socio - economic conditions of nineteenth - century urban, industrial America demanded of the church a reassessment of its understanding of people in society, it was the Social Gospel movement which arose to take seriously the reality of corporate sin and the need for corporate response.

Jeremy have been asking the holy spirit for his help with this and in regards to the lame man that Jesus healed I do nt believe that sin was the issue for him just like the blind man was it his parents or did he sin the answer was neither but so that God would be glorified.What was the sin that may have been worse for him.The two situations are related of the woman caught in adultery the key words being go and sin no more only two references in the bible and will explain later the lame man we see at first his dependency on everyone else for his needs he cant do it he is in the best position to receive Gods grace but what does he do with it.Does he follow Jesus no we are told he goes to the temple and Jesus finds him now that he has his strength to do things on his own what his response to follow the way of the pharisees that is what is worse than his condition before so he is warned by go and sin no more.We get confused because we see the word sin but the giver of is speaking to him to go another way means death.Getting back to the two situations of the woman caught in adultery and the lame man here we see a picture of our hearts on the one our love for sin and on the other the desire to work out our salvation on our terms they are the two areas we have to submit to God.My experience was the self righteousness was the harder to deal with because it is linked in to our feelings of self worth and self confidence so we have to be broken so we are humble enough to realise that without God we can do nothing our flesh hates that so it is a struggle at first to change our way of thinking.brentnz

The driving force behind this process — i.e., the «factors making for growth in the halakhah» — is, first, the «necessity to respond to new external conditions — social, economic, political, or cultural — that pose a challenge or even a threat to accepted religious and ethical values,» and, second, the «need to give recognition to new ethical insights and attitudes and to embody them in the life of the people, even if there [is] no change in objective conditions.»

A pious life may flourish for a brief time, but unless it leads to a more caring and responsible relationship with other human beings and to efforts to change conditions that cause human need and suffering, it will most likely not endure.

This grain - based diet can cause changes in the ph in cows, creating many abnormal physiological conditions in the cow which can increase the need for the use antibiotics.

Perhaps most importantly, in the 1990s, the market got a much - needed $ 30 million, years - long renovation that introduced heating and air - conditioning and even more critical changes, like fixes for the hole - riddled ceiling.

«I've heard so much about it from my dad: how difficult the stages are, how the conditions can change in an instant from snow to rain or bright sunshine and, of course, how you need nerves of steel for some of those mountain passes and hairpins.»

for posting that... conditions are out of control... his tactics aren't working, he is arrogant, a bad loser, always finding someone to blame for a lose, boring style of play... we need a change for Christ sake... you idiot should something better to post

The air conditioning was a bit poor in our room — to be honest we didn't really need it for the first 4 nights as there was a real strong wind on an evening which kept things nice and cool but half way through our stay the wind suddenly dropped and the room was stifling — Reception actioned this immediately and sent an engineer to our room — who couldn't get it fixed although it did get marginally better — reception offered to change our room but again this was more hassle than it was worth by this point during our stay so they provided us a fan instead which did the job.

Don't forget that for your experiment to be a fair test you need to change just one condition and keep the rest constant, for example if you're investigating whether a vitamin tablet works better than alka seltzer, you'll need to keep the amount of water in the canisters the same, and shake each the same amount (or not shake at all).

I / we agree that if any material change (s) occur (s) in my / our financial condition that I / we will immediately notify BSHFC of said change (s) and unless Baby Safe Homes Franchise Corporation is so notified it may continue to rely upon the application and financial statement and the representations made herein as a true and accurate statement of my / our financial condition.nI / we authorize Baby Safe Homes Franchise Corporation to make whatever credit inquiries / background checks it deems necessary in connection with this application and financial statement.nI / we authorize and instruct any person or consumer reporting agency to furnish to BSHFC any information that it may have to obtain in response to such credit inquiries.nIn consideration of the ongoing association between Baby Safe Homes and the undersigned applicant (hereinafter u201cApplicantu201d), the parties hereto have entered into this Non-Disclosure and Non-Competition Agreement.nWHEREAS, in the course of its business operations, Baby Safe Homes provides its customers products and services which, by nature of the business, include trade secrets, confidential and proprietary information, and other matters deemed material or important enough to warrant protection; and WHEREAS, Applicant, by reason of his / her interest in Baby Safe Homes and in the course of his / her duties, has access to said secrets and confidential information; and WHEREAS, Baby Safe Homes has trade secrets and other confidential and proprietary information, including procedures, customer lists, and particular desires or needs of such customers to which Applicant has access in the course of his / her duties as an Applicant.nNow, therefore, in consideration of the premises contained herein, the parties agree as follows Applicant shall not, either during the time of his / her franchise evaluation with Baby Safe Homes or at any time thereafter either directly or indirectly, communicate, disclose, reveal, or otherwise use for his / her own benefit or the benefit of any other person or entity, any trade secrets or other confidential or proprietary information obtained by Employee by virtue of his / her employment with Baby Safe Homes, in any manner whatsoever, any such information of any kind, nature, or description concerning any matters affecting or relating to the Baby Safe Homes business, or in the business of any of its customers or prospective customers, except as required in the course of his / her employment by Baby Safe Homes or except as expressly authorized Baby Safe Homes Franchise Corporation, in writing.nDuring any period of evaluation with Baby Safe Homes, and for two (2) years thereafter, Applicant shall not, directly or indirectly, induce or influence, divert or take away, or attempt to divert or take away and, during the stated period following termination of employment, call upon or solicit, or attempt to call upon or solicit, any of the customers or patrons Baby Safe Homes including, but not limited to, those upon whom he / she was directly involved, or called upon, or catered to, or with whom became acquainted while engaged in the franchise evaluation process of a Baby Safe Homes franchise business.

Information for patients and the public will help enforce the step change needed in antimicrobial prescribing, particularly for conditions like coughs and colds that may get better without such intervention in the large majority of cases.

As global climate change continues, scientists expect more droughts, heat stress and insect pests — creating need for new varieties of agricultural plants with diverse qualities that will let them cope and adapt to quickly changing conditions.

Research needs still not met Luce said those on the front lines of forest management have a lot to think about, and planning specifically for how climate change will impact drought conditions is «probably at the early stages.»

«We find the conditions for brines to be produced, but if you want to measure them directly you need some other kind of measurement,» he says, such as an instrument that can look for changes in electrical conductivity.

«Now we need to determine if the disease process or the extended antibiotic regimen is responsible for the changes we identified so that we can effectively care for the medical condition while minimizing any unintended, and potentially, far - reaching effects.»

It's unclear whether diving changes are positive or negative for belugas, and studies on body condition and health are needed to understand the implications of these changes, she added.

«The task,» Millikan wrote, «of learning to substitute stored solar energy for muscular energy — the great underlying cause of most of the changes in man's activities and living conditions — has been learned within the past eighty years and will never need to be learned over again.»

«Changing climate conditions are already happening,» says Eileen Claussen, president of the Pew Center on Global Climate Change, which today released a report on regional impacts in the U.S. «It is clear that there is an immediate need for strong national and international policy action.»

But Kan said more research is needed to understand the changes in microbial communities with biochar and to determine the optimum conditions for anaerobic digestion of manure before researchers can build a scale version that can be tested and eventually applied to scale for a working dairy.

But the remaining 60 % to 70 % — who take the drugs for more common conditions such as indigestion and heartburn — probably don't need them or should try lifestyle changes before resorting to medication, he adds.

If you have a medical condition, talk to your doctor before making changes because this plan can reduce your need for medication.

I «did GAPS» before it became trendy among health circles, with it being a means of healing many serious medical conditions; I am so grateful not to have medical needs as my catalyst for changing my behaviors.

If you have a medical condition then make sure to talk to your doctor before making any changes, because this diet can drastically reduce your need for medication!

However, the ever - changing weather conditions, high pollution and stressful lives call for the need of an intense skin care regimen.

No matter how well a SD / SB relationship could appear to be going, it could suddenly, without warning, come to a screeching halt for any type or number of factors, such as his conditions or needs changing, discovery, impulse, or (God - forbid) fatality, especially in the instance of having a significantly older Sugar Daddy this isn't unheard of.

The Invisible War features hard - hitting interviews with high - ranking military officials and members of Congress that reveal the perfect storm conditions that exist for rape in the military, its history of cover - up, and what can be done to bring about much needed change.

We also need to be able to track the debt gap with greater frequency, as contextual factors — including economic conditions, financial aid policies, and the role of for - profits — can change quickly.

However, the heavy emphasis on keeping these schools supplied with teachers is focusing the energy for improvement on recruitment rather than on the need to change the conditions that make these schools so hard to staff in the first place.

For this they will need versatility i.e. breadth as a hedge against rapidly changing conditions, an increased capability i.e. depth to engage with complex challenges, along with a diverse set of competencies such as adaptability, increased collaboration between cultures, etc. towards the goal of a sustainable humanity via fulfilled individuals.

«There's a sort of unarticulated, growing understanding that we've conceived the job of school leader wrong for contemporary needs and conditions, and that it needs to be changed,» said Thomas Sobol, an education professor at Teachers College, Columbia University, and a former New York state schools chief.

This new Partnership Forum would be able to propose changes to a draft remit for pay and conditions and set the agenda for any other issues that needed to be considered.

During my final studies relating to personality and social psychology [6] I suggested that where there hardly seems to be a need for a Survival of the Fittest - mode, we now are confronted within the conditions of Western society by a change to Psychological Survival, and our brain attributes and functions need to be adjusted as such.

Very few principals have systematically - collected evidence about the school and classroom conditions that would need to change for achievement to improve.

Very few principals had systematically - collected evidence about the school and classroom conditions that would need to change for their students «achievement to improve.

«The team grew in its ability to identify aspects of teacher practice and other system conditions that needed to change in order for Springdale to make even more significant gains.

Everything from grading policies and assessments, to bell schedules and how teachers and students spend their time will need to change in order to create the conditions for successful implementation.

Teachers reported, however, that school conditions, such as budgets and support for technology PD, still varied among districts which may influence the changing pace of teachers» technology PD needs.

Given you are driving the car 2 - 4 times a month for about 100 miles, you don't need to do anything special to keep anything in the car in good condition besides the typical maintenance (oil change, etc.).

Good article, last year I bought a Honda Pilot 2009, from Luther Hopkins in MN, they told us, it is was in perfect condition, 4 months later we took it back for an oil change, and they gave us a long list of parts that need to be replace, even the tires.