Sentences with phrase «conditions of hypoxia»

Not exact matches

Hypoxia - inducible factor 1α (HIF - 1α), an oxygen sensor that controls the expression of various genes for glucose metabolism under conditions of low oxygen levels, is the most well documented substrate of the von Hippel - Lindau (VHL) enzyme.

Recent studies showed that low oxygen conditions increase levels of a family of proteins known as HIFs, or hypoxia - inducible factors, that turn on hundreds of genes, including one called NANOG that instructs cells to become stem cells.

Owing to the difficulties involved in hypoxia, intense cold and doing exercise in conditions of little food, climbing up to high altitudes leads to routinely resorting to nutritional ergogenic aids or drugs.

So, any condition that increases hypoxia increases the risk of sickling and crisis pain.

Although a person's tolerance to hypoxia (lack of oxygen) varies according to differences in innate physiology and physical conditioning, no one is immune.

Of the 119 genes upregulated following hypoxia, 72 % remained upregulated after a 24 h period of recovery under normoxic conditionOf the 119 genes upregulated following hypoxia, 72 % remained upregulated after a 24 h period of recovery under normoxic conditionof recovery under normoxic conditions.

Mootha and his team had hoped to find benefits for more moderate low - oxygen conditions, such as intermittent periods of hypoxia or slightly higher levels of oxygen.

Under hypoxic conditions activates the transcription of over 40 genes, including, erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia.

They found that exosomes derived from older children's cells were only reparative if they were subjected to hypoxic conditions (lack of oxygen), while exosomes from newborns» cells improved rats» cardiac function with or without hypoxia.

Tumors thrive in a low oxygenated environment and this condition known as hypoxia promotes the invasion of cancer and its growth (1).

The effects of eutrophication on carbonate chemistry can exceed that of OA from anthropogenic CO2 by either increasing pH, when enhanced CO2 uptake by primary producers prevails (Borges and Gypens 2010), or by decreasing pH, where enhanced respiratory CO2 release prevails (Cai et al. 2011), a condition often associated with coastal hypoxia (Feely et al. 2010).

Bryan, I'm still waiting for an acknowledgement of the scientific inaccuracy of your previous comments, in which I was accused of promoting «junk science» regarding the conditions under which source rocks for oilfields form (as related to the quite relevant and topical issue of reduced thermohaline circulation and bottom water hypoxia).

Global change will shift current baseline conditions of pH and temperature, as well as those of other stressors (e.g. hypoxia, precipitation patterns / salinity), challenging the physiological capacity of resident biota [5,10,11,22].