Sentences with phrase «conduct efficacy studies»

Next steps will be to conduct efficacy studies to show whether reducing mutant huntingtin can slow down disease progression.

We then discuss the implications of using different observation procedures on both the statistical power and the monetary costs of conducting the efficacy study.

Not exact matches

Actual results and the timing of events could differ materially from those anticipated in the forward - looking statements due to these risks and uncertainties as well as other factors, which include, without limitation: the uncertain timing of, and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and studies of eptinezumab sufficient to achieve a positive completion; the availability of data at the expected times; the clinical, therapeutic and commercial value of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing on the intellectual property rights of others; the uncertain timing and level of expenses associated with Alder's development and commercialization activities; the sufficiency of Alder's capital and other resources; market competition; changes in economic and business conditions; and other factors discussed under the caption «Risk Factors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sec.gov.

Instead, it will conduct a Phase 1b / 2a study that will use «an improved cell processing technique to hopefully improve efficacy,» Fein noted.

Dreweke pointed to a study detailing the increased use of long - acting reversible contraceptives (such as IUDs and implants) among teens; although the study was only conducted among women who already used contraception, the efficacy of longer - acting contraceptives is higher than those of other birth control methods.

Thus, future research on human needs to be conducted to study the efficacy of VCO as rewetting agent on dry eye patient.

After obtaining the necessary permits and approvals, an independent community nutrition study will be conducted to evaluate the efficacy of Golden Rice; in other words, whether or not it improves vitamin A status.

In 2001, a Swiss study was conducted to investigate the efficacy of using compression stockings during pregnancy as a method of preventing varicose veins.

The company plans in October to conduct a separate test specifically to study the seasonal flu vaccine's effectiveness among 480 elderly participants (a demographic often encouraged to get seasonal flu shots), and Phase III efficacy trials across a larger set of demographics are scheduled to begin early next year.

And scientists who conduct human challenge studies, which typically involve a few dozen participants, say they have critical benefits: In addition to saving time and money, they can reveal harm caused by a potential drug or vaccine before it enters large - scale human efficacy trials.

They will also be conducting clinical studies to examine the efficacy of delivering collagen for cosmetic and skincare purposes.

Medical psychologist Jack D. Edinger of Duke University and his colleagues conducted a two - and - a-half-year study of 75 adults suffering from sleep maintenance insomnia in order to assess the efficacy of a form of cognitive behavioral therapy (CBT), as compared with relaxation therapy and placebo therapy.

Geisbert says the efficacy of the mix may have been due to the antibodies; past studies that he and others have conducted have found no effect on Ebola from interferon itself, he says.

«To prove the efficacy we need double - blind control studies, which is very difficult to conduct in such settings,» he says.

«We are exploring alternative directions for developing this compound, including potential use of the animal efficacy rule,» Cihlar said, referring to a regulatory mechanism under which the U.S. Food and Drug Administration may consider efficacy findings from adequate and well - controlled animal studies of a drug in cases where it is not feasible or ethical to conduct human trials.

The current study — conducted in three neighborhoods of Merida, Mexico — measured the efficacy of indoor residual spraying against adult Aedes aegypti mosquitoes in houses treated with either deltamethrin (to which the local mosquitoes expressed a high degree of resistance) or bendiocarb (another insecticide to which the mosquitoes were fully susceptible), as compared to untreated control houses.

The study, conducted at Harvard University, represents the first evaluation of the protective efficacy of a candidate global HIV antigen strategy in nonhuman primates.

Based on proof - of - concept pre-clinical studies indicating robust efficacy and favorable safety profile, the company is now advancing to conduct a clinical trial testing the efficacy of this new treatment.

The correlate study conducted by the US Military along with Duke University has found clues that will enable scientists to improve the current vaccine's efficacy level.

In this presentation, we discuss data from studies conducted with academic, clinical, and industry collaborators that demonstrates the utility of the system as a more predictive, human - relevant alternative for efficacy and safety testing of new chemical entitites.

A planned interim efficacy analysis was conducted based on 82 patients who completed at least 183 days of treatment, withdrew from the study, or died.

Its Clinical Trials Center conducts 13 - 15 clinical studies per year, and in December initiated a Phase 2 clinical trial of an Ebola vaccine following its groundbreaking first - in - human testing of the Ebola vaccine that showed efficacy in Guinea last year.

Researchers at the Murdoch Children's Research Institute in Melbourne, Australia, conducted a study to evaluate the efficacy of administering the rotavirus vaccine starting at birth.

Using data from the AHRQ report, the Institute for Clinical and Economic Review (ICER, 2011) conducted a cost - effectiveness modeling study, assuming that transcranial electrical stimulation and electroconvulsive therapy have equivalent efficacy.

To see if a product actually protects against HIV and AIDS, an efficacy study is conducted, which is often called a phase 3 study.

Most therapeutic research involving the testing of new drugs is conducted in highly regulated phases that study dosage, safety, efficacy and long - term side effects:

Additional studies are currently being conducted to determine the safety and efficacy of these natural health supplements.

Low - carbohydrate advocates are masters of documenting the efficacy of their philosophy using studies with small population sizes conducted over short time periods — often over weeks or months.

Lee and colleagues conducted an overview of 10 systematic reviews that evaluated the efficacy of aromatherapy (with and without massage) in reducing hypertension, depression, anxiety, pain relief, and symptoms of dementia.26 The authors determined that, though three of the reviews were of good methodological quality, many of the primary studies they evaluated were not.

Clinical Outcomes of a Diagnostic and Treatment Protocol in Allergy / sensitivity Patients Alternative Medicine Review 2001 (Apr); 6 (2): 188 — 202 ~ FULL TEXT This level II outcome study was conducted to examine the efficacy and toxicity of a diagnostic and treatment protocol using electrodermal screening (EDS) in allergy / sensitivity patients.

I appreciate this opportunity to offer the perspective of the social studies educational research community in response to the interview of Joseph South, director of the U.S. Office of Educational Technology, conducted by Working Group E of the Jefferson Education initiative on the Efficacy of Educational Technology Research (Bull, Spector, Persichitte, & Meier, 2017).

This study was conducted in two phases including focus groups to determine teachers» perceptions on the effectiveness of arts integration among their special needs populations and a pilot project that examined the efficacy of rubrics in measuring various skill areas.

Dr. Bry's systematic program of prevention research has included studies that: 1) search for precursors that differentiate adolescents who will develop conduct or substance use problems from those who will not and environmental factors that might reduce or buffer those precursors; 2) investigate whether these factors actually precede or reduce future problems; and 3) test the outcome efficacy and effectiveness of experimental methods to modify these factors.

This study was conducted to investigate eighth - grade science teachers» self - efficacy during the implementation of a new, problem - based science curriculum.

This study documents the efficacy of a function - based intervention conducted using a multiple baseline across

Vannatta and Fordham (2004) conducted a similar study and examined the relationship between a variety of teacher variables — amount of professional development, amount of technology training, years of teaching, self - efficacy, and philosophy — and their technology use for teaching.

To assess our research questions about the efficacy of using online social networks with preservice history teachers, we conducted a design research study.

In support, district leaders cited a study on the efficacy of K - 8 schools, which had been conducted by researchers at Johns Hopkins University and published in a respected journal.

Iris Educational Media is conducting a research study to determine the efficacy of We Have Skills, our multi-media curriculum that delivers classroom behavior lessons directly to students, K - 3.

The safety and efficacy of Pet Dental Services was proven through a double blind study conducted with a boarded veterinary dental specialist.

About the Study The study, «Efficacy and safety of oclacitinib for the control of pruritus and associated skin lesions in dogs with canine allergic dermatitis,» was conducted as a double - masked, placebo - controlled clinical trial aimed to evaluate the safety and efficacy of APOQUEL compared with plaStudy The study, «Efficacy and safety of oclacitinib for the control of pruritus and associated skin lesions in dogs with canine allergic dermatitis,» was conducted as a double - masked, placebo - controlled clinical trial aimed to evaluate the safety and efficacy of APOQUEL compared with plastudy, «Efficacy and safety of oclacitinib for the control of pruritus and associated skin lesions in dogs with canine allergic dermatitis,» was conducted as a double - masked, placebo - controlled clinical trial aimed to evaluate the safety and efficacy of APOQUEL compared with Efficacy and safety of oclacitinib for the control of pruritus and associated skin lesions in dogs with canine allergic dermatitis,» was conducted as a double - masked, placebo - controlled clinical trial aimed to evaluate the safety and efficacy of APOQUEL compared with efficacy of APOQUEL compared with placebo.

In the next paragraph we will look at how it works, what dogs it benefits the most and some studies conducted on the efficacy of this herb.

A controlled laboratory study was conducted to evaluate the efficacy of four commercial products administered as a single treatment for the prevention of heartworm disease caused by Dirofilaria immitis in dogs.

Dr. O'Haire says the valuable data from the pilot study helped secure the NIH R21 grant to conduct the large - scale, clinical trial to further investigate the efficacy and role of service dogs for military veterans with PTSD and their spouses.

Studies to establish the safety and efficacy of Clomicalm Tablets in dogs less than 6 months of age have not been conducted.

Efficacy was confirmed in a one - year duration of immunity study in which none of the vaccinated animals were infected with rabies when challenged 12 months after a single dose of DEFENSOR.4 During a field safety study conducted in 200 ferrets, no significant post-vaccination reactions were observed.5

There was also a study conducted on the efficacy of anesthesia - free dental cleanings.

Efficacy was evaluated in two studies conducted on New Year's Eve in Europe * to explore treatment effect under the actual conditions of use with an authentic noise stimulus: fireworks.

Case in point: Nielsen recently conducted a study to find out just how effective branded content is, and if there are any elements that increase its efficacy, compared to more traditional forms of advertising.

San Francisco - based consulting and engineering firm URS will conduct the study, which Newsom announced Tuesday, and assess the best time to harness wave - energy, the costs associated with transmitting energy from ocean to land and the efficacy of existing technologies, among other subjects.