The His274 → Tyr274 (H274Y) mutation
confers oseltamivir resistance on N1 influenza neuraminidase but had long been thought to compromise viral fitness.
Not exact matches
They describe virus strains with mutations known to
confer high resistance to
oseltamivir, which they isolated from a 13 - year old girl and a 35 - year old woman killed by H5N1.
The virus with this mutation remains sensitive to the antiviral drugs,
oseltamivir and zanamivir, and studies show that currently available pandemic vaccines
confer protection.