Not exact matches
Precisely as we humans, every dog is likely to carry genetic predisposition for some
inherited disorder, so we expect these numbers to grow as the numbers of tested
disease variants, breeds, and dogs further increase,
confirms Dr. Donner.
What invasion biology has failed to
confirm, I wrote, isn't their harmfulness but rather the
disease metaphor
inherited from the 1950s.
Strong evidence from a mouse model of the
disease further
confirms these mutations as a cause of aortic
disease, and, together, the results point toward possible strategies for managing this
inherited form of TAAD.
CSIC researcher adds: «We have
confirmed that mutation is found in both copies of the gene, one
inherited from the father and the other one
inherited from the mother, in the four women affected by the
disease, causing an absolute absence of STAG3 protein and meiotic cohesin complex in these women.
The distribution of
disease genes
confirms genetic heterogeneity and opens new perspectives in genetic testing in patients with LVNC and their relatives at high risk of
inheriting the cardiomyopathy.