Sentences with phrase «congenic mouse line»
Identification of a congenic mouse line with obesity and body length phenotypes.
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It should be noted that the phenotype of this C57BL / 6J - congenic line (Stock No. 028867 Gad2 - IRES - Cre knock - in (C57BL / 6J)-RRB- could vary from that originally described for mice on other genetic backgrounds.
Laboratory Animal Genetic Services (LAGS) provides MD Anderson investigators with cost - effective, customized genome scans using polymorphic genetic markers to support rapid congenic line development and background strain characterization for mice and rats.
Spontaneous expansion of the CAG repeat stretch in the CAG 140 KI mouse model, which carries a chimeric mouse / human exon 1 containing around 125 CAG repeats and the human polyproline region inserted in the murine huntingtin gene (Menalled et al., 2003, Hickey et al., 2008), has recently led to a new KI line that carries around 190 CAG repeats (CAG 190 KI) in a congenic C57Bl / 6J background.