Sentences with phrase «congenic strains»

In the present study, we used a combination of BAC clone contig construction, polymorphism analysis of DNA from congenic strains, and sequence mining of the human orthologous region to generate an integrated map of the Idd10 region on mouse chromosome 3.

This collection, assembled and maintained by Dr. Lynn Lamoreux while at Texas A&M University, contains pigment mutant mouse strains, virtually all as congenic strains on a C57BL / 6 background.

Confirmation of quantitative trait loci influencing methamphetamine - and opioid - induced locomotor stimulation using B6.D2 congenic strains Camron Bryant, Dept of Human Genetics, University of Chicago, USA

To provide additional genetic information for congenic strains, background strain information can be ascertained using MegaMUGA, a low - cost high - density genotyping platform.

Lin C, Fesi BD, Marquis M, Bosak NP, Lysenko A, Koshnevisan MA, Duke FF, Theodorides ML, Nelson TM, McDaniel AH, Avigdor M, Arayata CJ, Shaw L, Bachmanov AA, Reed DR. Adiposity QTL Adip20 decomposes into at least four loci when dissected using congenic strains.

Of note, Dr. Warden's lab reports that, at least once during backcrossing, a heterozygous female was bred to a C57BL / 6J inbred male (thus the Y chromosome of the congenic strain is of C57BL / 6J origin).

The resulting C57BL / 6J - congenic strain, called Gad2 - IRES - Cre knock - in (C57BL / 6J), were sent to The Jackson Laboratory Repository in 2016 as Stock No. 028867.

Genes affecting autoimmune type 1 diabetes susceptibility in the nonobese diabetic (NOD) mouse (Idd loci) have been mapped using a congenic strain breeding strategy.

Not exact matches

The unit provides genetic testing services using a combination of both microsatellite and single nucleotide polymorphism (SNP) panels for characterizing and selecting breeders in a wide variety of inbred mouse strains subsequently used for the generation of congenic animals.

In contrast, the Speed Congenics program requires a maximum of five generations where candidate breeders are genotyped at each generation and those with highest percentage of the desired strain are selected to father the next generation.

Laboratory Animal Genetic Services (LAGS) provides MD Anderson investigators with cost - effective, customized genome scans using polymorphic genetic markers to support rapid congenic line development and background strain characterization for mice and rats.

Many of the strains received have been made congenic, including 87 alleles on a C57BL / 6NCrl background, and several on other backgrounds including BALB / cJ and 129S6 / SvEvTac.

DartMouse ™ offers clients a marker - assisted congenic breeding strategy to produce congenic mice with > 99 % recipient strain genetic purity in half the time (5 generations; 1.25 - 1.5 years) instead of the more practiced 10 - 20 generations, which can take greater than 5 years.