Sentences with phrase «congenital zika»

Title: Adaptive feeding intervention and monitoring program for infants with congenital Zika syndrome.

«Among infants of mothers exposed to Zika virus during pregnancy, the absence of microcephaly at birth does not rule out congenital Zika virus infection or the presence of Zika - related brain abnormalities,» according to a news release from the U.S. Centers for Disease Control and Prevention.

Conclusions and Relevance Although the full spectrum of adverse reproductive outcomes caused by Zika virus infection is not yet determined, a distinctive phenotype — the congenital Zika syndrome — has emerged.

Longitudinal monitoring of the infants with possible congenital Zika virus infection is essential to fully characterize the outcomes.

Characterizing the Pattern of Anomalies in Congenital Zika Syndrome for Pediatric Clinicians.

The immense cost of raising Brazil's babies with congenital Zika syndrome is straining poor families and the government that supports them.

Based on that, we recommend using the term congenital Zika syndrome instead of microcephaly associated with Zika virus infection, which involves a spectrum of changes, including other neurological and fetal development manifestations.

«For couples wanting to get pregnant or thinking of becoming pregnant there is a different balance of risks because of the dangers of microcephaly and congenital Zika syndrome.

Interferon - α / β signaling is pathogenic in a mouse model of congenital Zika virus infection.

Doctors have coined a new name for their disease, «congenital Zika syndrome» — a sign of how much they have to learn.

Dr. Tovar - Moll noted that the researchers are continuing to investigate the central nervous system changes induced by congenital Zika virus infection to better understand the spectrum of the changes they have seen.

The researchers performed a retrospective review of imaging and autopsy findings associated with congenital Zika virus infection found in the Instituto de Pesquisa in Campina Grande state Paraiba (IPESQ) in northeastern Brazil, where the infection has been severe.

Congenital Zika virus syndrome — a pattern of birth defects found among fetuses and babies infected with the virus — is a newly identified condition that occurs when women are infected during pregnancy.

«Although congenital Zika infection is less prevalent in the U. S. than CMV, many people have heard of the Zika virus but fewer are familiar with cytomegalovirus,» Diener said.

In a new paper published this week in the American Journal of Medical Genetics, first author Miguel del Campo, MD, PhD, associate professor in the Department of Pediatrics at University of California San Diego School of Medicine, and colleagues in Brazil and Spain, describe the phenotypic spectrum or set of observable characteristics of congenital Zika (ZIKV) syndrome, based upon clinical evaluations and neuroimaging of 83 Brazilian children with presumed or confirmed ZIKV congenital infections.

«It's safe to say that most children with congenital Zika syndrome will have major impairments that will not be easily treated by surgery, medication or therapy services,» Bailey said.

The impact of congenital Zika syndrome on families will be substantial and will last a lifetime, given its severity and uncertainty about long - term outcomes for infants.

«Family impact of congenital Zika syndrome likely to last a lifetime: Supplement in Pediatrics synthesizes research on Zika.»

What do we know and what can we expect regarding the cognitive, behavioral, and functional development of children with congenital Zika syndrome?

Funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, researchers are following 200 infants with congenital Zika syndrome and their families to understand the ongoing health impact, why some babies affected by the virus develop more normally than others, and if more positive prognoses are linked with family or environmental characteristics.

Congenital Zika syndrome refers to the pattern of birth defects among fetuses and infants of mothers infected with Zika virus during pregnancy.

Since 2016, when Zika was declared by the World Health Organization as a public health emergency of international concern, the virus has become established in more than 80 countries, infected millions of people, and left many babies with birth defects (collectively called congenital Zika syndrome).

«Thus, it is tempting to speculate that the alterations induced by Zika virus on the host cytoskeleton might be connected to the underlying physio - pathological mechanisms that link congenital Zika virus infections to microcephaly and neurodegenerative disorders.»

«Infants with congenital Zika virus syndrome suffer serious visual impairment: 100 % of Brazilian infants with confirmed and suspected Zika were born with vision problems.»

Although one of the most serious consequences of the Zika virus (ZIKV) in infants is microcephaly, there is a broad collection of anomalies now known as congenital Zika syndrome (CZS).

Not exact matches

Zika is transmitted primarily through mosquito bites and has been linked to congenital microcephaly and other serious brain defects among babies born to mothers who had the virus.

«Our findings suggest Zika virus should be officially added to the list of congenital infections,» said Thália Velho Barreto de Araújo of Brazil's Pernambuco University, who also worked on the research team.

The researchers are beginning to use their model to test whether Zika virus, and other pathogens associated with congenital disease, can infect placental cells and / or cross the placental barrier.

The fetal disease caused by Zika virus could soon have a new name: Zika virus congenital syndrome.

«How Zika virus induces congenital microcephaly.»

«We've been seeing growing evidence of the association between Zika and congenital central nervous system malformations, not just microcephaly, since the first cases were picked up,» says Wim Van Bortel, senior expert on vector - borne diseases at the European Centre for Disease Prevention and Control in Solna, Sweden.

The team who found a range of fetal conditions beyond microcephaly, all linked to the virus, suggest calling it Zika virus congenital syndrome

Patricia Garcez examines the cellular and molecular effects of Zika virus congenital syndrome during brain development.

Zika infection associated with congenital brain abnormalities is one of the eleven virus diseases that, according to World Health Organization, needs urgent research and drug development attention.

In particular, ongoing longitudinal cohort studies can show the long - term neurological and psychiatric consequences of congenital and after - birth Zika infection.

As evidence grew for a causal link between Zika infection and microcephaly and other serious congenital anomalies (1), the World Health Organization (WHO) declared the Latin American Zika epidemic a public health emergency of international concern in February 2016 (2).

They note that the rubella epidemic of the 1960s, when tens of thousands of babies were born with congenital rubella syndrome in the United States, can provide important lessons learned that may be directly applicable to Zika research.

Zika virus infection during pregnancy has been linked to congenital brain abnormalities, including microcephaly, and Zika virus is a trigger of Guillain - Barré syndrome.

It notes some of the critical scientific questions regarding Zika that deserve further exploration, including: whether certain viral mutations occurred to facilitate its geographical spread; if different species of Aedes mosquitoes are capable of transmitting Zika and what that may mean for future transmission; what is apparently unique to Zika compared to other more well - known flaviviruses, such as dengue, that can explain why it can cause congenital infections, neurological conditions and encephalitis, transmit sexually and persist for long periods of time in multiple parts of the human body; and whether preexisting immunity to other related flaviviruses may impact Zika exposure and infection.

While the Zika virus typically causes a relatively mild illness, infection during pregnancy can cause microcephaly and other devastating congenital malformations.

The study comes in the wake of an ongoing Zika epidemic and an explosion of cases involving fetal death, microcephaly (born with severely decreased head size), and other congenital birth defects.

They represent the greatest health crisis because a Zika infection during the first trimester confers the greatest risk of congenital microcephaly.»

«We're highly encouraged by these preclinical findings demonstrating the ability of our mRNA vaccine to provide robust prevention of maternal transmission of Zika and protection against congenital defects,» said Giuseppe Ciaramella, Ph.D., Chief Scientific Officer of Moderna's infectious disease - focused venture, Valera, and an author on the paper.

Contracted through the bite of an infected mosquito or through sexual or other modes of transmission, Zika virus (ZIKV) infection can be prenatally passed from mother to fetus.1 The virus was first identified in the region of the Americas in early 2015, when local transmission was reported in Brazil.2 Six months later, a notable increase in the number of infants with congenital microcephaly was observed in northeast Brazil.3, 4 Clinical, epidemiologic, and laboratory evidence led investigators to conclude that intrauterine ZIKV infection was a cause of microcephaly and serious brain anomalies.5 - 7 However, as with other newly recognized teratogens, these features likely represent a portion of a broader spectrum.

Publication in Cell Demonstrates Moderna's Zika mRNA Vaccine Prevents In Utero Transmission of Zika Virus in Mice, Protects Against Zika - Related Congenital Damage

Other congenital infections are known to cause hearing problems, but this is one of the first times its been documented among children with Zika - related microcephaly.

Based on a newly published systematic review of current research, WHO has reaffirmed its position that Zika virus infection during pregnancy is a cause of congenital brain abnormalities, including microcephaly, and refined its position on the relationship between Zika virus infection and Guillain - Barré syndrome, stating that Zika virus infection is a trigger of Guillain - Barré syndrome.