Sentences with phrase «consider potential effects»

«For instance, efforts to block the infection - enhancing activity of these semen amyloids for STD prevention must now consider the potential effects of such interventions on sperm quality and immune recognition of male antigens.»

Our source data on this relationship18 considers the potential effect of unobserved confounding and argues that such confounding is unlikely to explain the adjusted association between breastfeeding and hypertension.

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

«How can any regulator, in this case the Nebraska PSC, even begin to make an informed decision about [Keystone XL] without considering pipeline safety, the risk of leaks and spills, and the potential environmental effect of spills?

consider the evidence available from both Australian and international scientific research into the potential human health effects of PFAS exposure; and

Concerns have been raised about the potential effects of transgenic introductions on the genetic diversity of crop landraces and wild relatives in areas of crop origin and diversification, as this diversity is considered essential for global food security.

Conversely, there are potential negative effects of testing modifications that should be carefully considered before choosing to use them for your child.

Geared to both healthcare practitioners and nursing mothers, LactMed contains over 450 drug records with information such as potential drug effects and alternate drugs to consider.

Choosing a crib mattress made from organic materials is a wise choice when you consider the potential long - term effects that a synthetically produced crib mattress could cause for your child.

If you wish to avoid the potential negative effects of an EFM you may want to consider your options for giving birth in a birth center or at home.

The potential of being negative becomes clear when you consider the effects of acting on simple, unqualified majoritarianism, and the association with negativity becomes clear when you consider politicians today who are called populists.

The Department for Business, Innovation and Skills has warned the living wage «does not consider any potential adverse employment effects and — despite its name — is unlikely to be a well - targeted poverty measure».

Both studies are observational, so their interpretation needs to consider the potential impact of other factors before any firm conclusions can be drawn about cause and effect, they add.

Many factors are currently considered, including a measure's expected effect on patients and health care, potential for promoting improvement, scientific underpinnings, usability, and feasibility.

These factors have been long - studied for large dams, yet have been largely ignored for small dams — especially considering the potential cumulative effects of many small dams in a single river system.

The authors note that clinicians must consider medication efficacy, potential side effects, and possible medication - related adverse events when prescribing acute medications for migraine.

To inform this recommendation, it is important to consider how institutions currently monitor graduate student support and time to degree, as well as to better understand challenges to potential reductions in the duration of training, and strategies that may mitigate the effects of such changes.

«Additional studies should certainly be considered, but we hope that medical professionals will consider the positive potential of honey as a treatment given the lack of proven efficacy, expense and potential for adverse effects associated with the use of DM,» said lead study author Ian Paul, a pediatrician and associate professor of pediatrics.

A key issue in considering the decision has been the potential climate effects of natural gas versus coal.

Key concepts that were not considered in this study include the economic and health effects of cool pavements, and potential emissions savings from vehicle - road interactions (for example, smoother roads may translate to small improvements in fuel efficiency).

The point was further emphasized in a press release put out by Nature Nanotechnology this week: «These findings suggest that direct and indirect effects of nanoparticles on cells are equally crucial when considering the potential risks of their use in nanomedicine.»

Furthermore, only recently have researchers been able to consider both the ecological relationships among krill predators (e.g., niche overlap) and the potential effects of climate change on those relationships, specifically as they relate to the availability of their krill prey [14].

«Treatment is relevant for stroke recovery and outcome,» they write, «but should be used thoughtfully considering potential side effects.»

But our belief that natural is always good — and more natural is even better — can lead us to take alarming risks, treating these supplements like food without considering the potential side effects many have.

Although HT is the most effective treatment for managing most menopause symptoms, some women have considered herbal medicine because they're either not candidates for HT or are concerned about the potential side effects.

Introduction While a large body of research has reviewed the physiological effects of coffee consumption, only few studies have considered the potential relationships between coffee consumption, mood and emotion.

Because of the unique ability of Anabolic Steroids to boost muscle mass, it's used in professional, non-competitive, or competitive sports events are considered illegal due to the possibility of serious adverse effect which can also lead to a high potential of abuse.

Considering the many potential adverse health effects of insufficient sleep, it is not surprising that poor sleep is associated with lower life expectancy.

Although these results were modest, taking into account the size of the sample and the length of the study, the potential hypotensive effects of the Amazonian cherry are worth to consider; however, further studies will be of help in order to establish the relevance of camu camu for cardiovascular health.

Considering the potential weight loss benefits of adding coconut oil to your diet, this side effect may seem surprising.

When you are working to dampen inflammation and autoimmune flares associated with Hashimoto's hypothyroidism, the potential inflammatory effect of birth control pills on liver function is a factor to consider.

This is extremely low considering all the potential side effects, as well as the necessary diet and exercise plan.

In several studies, it had a potential effect on glycemic control and one study in particular, using 500 mg twice daily for 90 days, improved A1C levels (A1C levels are considered a reflection of average blood sugar levels over a 3 month period).

A small number of studies have considered a potential ergogenic effect of low and very low intakes of caffeine taken late in prolonged exercise.

To understand potential effects of flaxseed and how they may affect breast cancer, it helps to understand what flaxseeds are, and why some consider them a concern for women with a history of breast cancer.

Although Melatonin is considered a natural sleep aid, there are potential side effects to be aware of.

Although grape seed extract is considered generally safe, it has the potential for some side effects, like:

For some of the known beneficial effects of Dietary and potential Functional Fibers, see â $ Physiological Effects of Iso - lated and Synthetic Fibersâ $ and â $ Evidence Considered for Estimating the Requirement for Dietary Fiber and Functional Fiber.â $ Cellulose.

Summary estimates were calculated using a general variance - based method (random - effects model) with 95 % CIs.19 Because the potential confounders considered in multivariate analyses vary across studies, we used the parameter estimates in the most complex model, which typically include demographic, lifestyle, and dietary factors.

However, additional, longer term (≥ 1 y), randomized controlled trials are needed in this area, including those that investigate the optimal dose of pulses for weight control balanced with other factors worth considering, such as any potential negative effects (e.g. gastrointestinal tolerance, phytate effects of mineral absorption).

Data from human studies on adverse effects of consuming what may be considered as Functional Fibers (if suffi - cient data exist to show a potential health benefit) are summarized below under the particular fiber.

Parisian water was considered to have a negative effect on skin that could cause dryness and potential blemishes.

While she would never consider a potential film franchise shouldering a reported $ 40 million budget and a frightfully ardent fan base as anything akin to her art, Taylor - Johnson does manage to use her eye for the slow burn, honed in work like her 2004 video portrait of the soccer star David Beckham sleeping, to great erotic effect.

Considering the potential adverse effects and lack of evidence - based research on ESA programs, state policy makers need to take a step back on ESA programs, and ensure the implications of such programs are fully considered before enacting them into law.

This chain of effects is reflected in the design of the evaluation plan, which consider potential mechanisms and mediators of impact, alongside investigation of ultimate benefits that may accrue to students.

When you assess fund performance, consider the effects of risk on potential return.

We have discussed the impact of credit inquiries in this post — the effect on your credit may be minimal considering the potential benefit.

[And God no, right now I'm not even going to consider a potential Trump Effect for Ireland... there's plenty of time to ponder Trump next year (or not)!]

If this is an option you choose, consider all of the potential side effects including stomach ulcers or digestive issues.

Your veterinarian always considers these potential side effects when prescribing a medication, with the goal of maximizing the positive effects of the drug and minimizing the unwanted side effects.