The proprietor of Technicolor, Herbert Kalmus, demanded that films shot using the process hire a «consultant,» usually his wife, Natalie, whose enthusiastic meddling and
consistent lack of taste earned her the nickname the Nuisance from directors like Michael Powell.
Overall, the side effects experienced by the patients were
consistent with that
of melanoma patients, except for the higher rates
of weight loss, dysgeusia (distortion
of taste), anemia (
lack of iron), increased creatine levels, and hepatic laboratory abnormalities.