Sentences with phrase «constitutive activity»

A cell signal pathway with constitutive activity requires no binding partner (ligand) to activate; instead, the signaling circuit continually activates itself.

The entity rises out of a constitutive activity analyzable into elements which are not actual entities.

Wherever the Spirit of Christ, which as the eschatological gift anticipates God's new creation in history, is present in its ecclesially constitutive activity, there is the church.

Not exact matches

It now follows that the constitutive principles of this association must also be legal in character; that is, an institutional process through which governing activities are properly determined must itself be coercively enforced.

It is, moreover, an activity that remains within and is constitutive of the subject — though it is not, as with Whitehead, a process of self - creation.

But Hartshorne effectively replies that, even if finite beings depend for their existence on the creative activity of God, it still remains true that if God had created a different world then He would have been somewhat different from the way He actually is by virtue of the fact that His perfect knowledge would have been of that world rather than of this world; and so the point still holds that divine cognitive relations to the creatures are partially constitutive of God.7

Thus in the marital act, spouses freely choose to instantiate their communion of persons in one flesh open to the gift of life in and through an act in which their bodily activity is as much the constitutive subject of what they are doing asis their act of choice.

In such acts «is the body's activity as much the constitutive subject of what one does asone's act of choice is»?

The Acks transcript contains an additional approximately 700b sequence at the 3 ′ - end, but overall sequence similarity with the kakusei transcript was conserved throughout the Acks transcript, including sequences corresponding to both the neural activity - inducible and constitutive - type kakusei transcripts (Figure 1A).

In 2005, the identification of an activating mutation in JAK2 (the V617F mutation) as a STAT5 - activating and disease - causing genetic alteration in a significant proportion of patients with myeloproliferative neoplasms (MPNs) has emphasized the oncogenic role of the JAK tyrosine kinases in hematologic malignancies.2 — 5 JAK2 is a member of the Janus tyrosine kinase family comprising three other mammalian non-receptor tyrosine kinases (JAK1, JAK3 and TYK2) that associate with cytokine receptors lacking intrinsic kinase activity to mediate cytokine - induced signal transduction and activation of STAT transcription factors.6 All JAKs share a similar protein structure and contain a tyrosine kinase domain at the C - terminus flanked by a catalytically inactive pseudokinase domain with kinase - regulatory activity, by an atypical SH2 domain and by a FERM domain that mediates association to the membrane - proximal region of the cytokine receptors.7, 8 Soon after the discovery of JAK2 V617F, we and others described that activating JAK1 mutations are relatively common in adult patients with T - cell acute lymphoblastic leukemia (ALL) and participate in ALL development allowing for constitutive activation of STAT5.9 — 11 Several STAT5 - activating JAK1 mutations were also reported in AML and breast cancer patients.10

A human serotonin transporter mutation causes constitutive activation of transport activity