Not exact matches
Yet in 1996 researchers found that women
consuming soy protein isolate had an increased incidence of epithelial hyperplasia, a condition that presages malignancies.45 A year later, dietary
genistein was found to stimulate breast cells to enter the cell cycle, a discovery that led the study authors to conclude that women should not
consume soy products to prevent breast cancer.46
These studies — which include analysis of the isoflavones
genistein, daidzein, malonylgenistin, and malonyldaidzin — show a limited impact of soy food intake on thyroid function, even when soy isoflavones are
consumed in supplement form at levels higher than expected from food.
Genistein Inhibits Both Estrogen and Growth Factor — stimulated Proliferation of Human Breast Cancer Cells Cell Growth & Differentiation 1996 (Oct); 7 (10): 1345 — 1351
Genistein is a naturally occurring dietary protein tyrosine kinase (PTK) inhibitor that is hypothesized to be responsible for the lower rate of breast cancer observed in Asian women
consuming soy.
Women who
consumed three or more bowls of miso soup containing about 25 mg
genistein daily had approximately half the risk of breast cancer.
With regard to breast cancer, Dees et al. have shown that dietary concentrations of
genistein may stimulate breast cells to enter the cell cycle; this finding led these authors to conclude that women should not
consume soy products to prevent breast cancer (29).