Not exact matches
Our data are also consistent with the contention that there is no
protein synthetic advantage gained by
consuming increasingly large servings of
protein in a single meal (7, 16).
Leucine stimulation of anabolic pathways is decreased in the presence of sufficient essential amino acids (EAAs)(69), indicating an increased basal
synthetic rate with adequate EAA ingestion, thus highlighting the importance of
consuming dietary
protein at levels above the current RDA during periods of energy deficit.
Furthermore, phosphorylation states of intracellular regulators of muscle
protein synthesis (mTOR, 70 - kDa S6 kinase, and eIF4E - BP1) were similar in pigs that
consumed a leucine - supplemented, low -
protein diet or a high -
protein diet without additional leucine, highlighting the potential
synthetic effect resulting from increased leucine intake.
In nature there are no
synthetic supplements, and dogs and wolves derive their nutritional needs by
consuming prey animals; muscle meat provides
protein; liver, kidney and tripe supply vitamins and minerals; bones and cartilage deliver calcium and phosphorus.