LA JOLLA — We all know how hard it is to find something small like a dropped
contact lens that blends into the background.
A prototype
contact lens for sustained drug release consisting of a thin drug - PLGA film coated with pHEMA could be used as a platform for ocular drug delivery with widespread therapeutic applications.
From October to March, Cardiff University Optometrists offer free eye examinations and
contact lens appointments for everyone.
• Soft
contact lens could help diabetes patients (Jan 2018) • Graphene patch detects glucose in sweat (Mar 2016) • Nanoporous thin - film device could help treat diabetes (Aug 2017)
Over on the news side today is an article I put together for Scientific American Online on some mysterious, ubiquitous, and sometimes - deadly red bacteria that are probably at this moment living in your shower grout and
contact lens case.
Mucin, on the other hand, adheres directly to
the contact lens, thus providing the eye with long - term protection.
«People with higher order aberrations often have irregularities in the shape of the cornea, and this irregular shape makes it very difficult to have
a contact lens that will fit.
Thus, a group of scientists led by Prof. Oliver Lieleg, professor for Biomechanics and head of the «Biopolymers and Bio-Interfaces» lab at the Munich School of BioEngineering, had the idea to apply the missing mucin directly to
the contact lens.
«We showed that the mucin passively adsorbs to
the contact lens material and forms a lubricating layer between
the contact lens and the cornea,» explains Benjamin Winkeljann, first author of the study.
They also provided used
contact lens storage cases, which were sent to a laboratory for culture studies to assess contamination.
«Hygiene practices affect
contact lens case contamination.»
Relationships between hygiene practices and
contact lens case contamination were assessed.
The new study highlights important hygiene habits to reduce contamination of
contact lens cases — including washing hands with soap and water, air - drying lens cases, and using matching lens cases and disinfecting solutions.
As in previous studies, contamination rates were high: 66 percent of
contact lens cases tested positive for bacterial or fungal contamination.
Many of the contaminants isolated from
contact lens cases were bacteria commonly identified in minor corneal infections (infiltrates), Dr. Willcox and coauthors note.
Participants completed a questionnaire regarding
their contact lens hygiene habits.
Contaminated
contact lens cases may contribute to complications, including potentially serious infections.
The contact lens concept isn't unheard of — Google has submitted a patent for a multi-sensor contact lens, which the company says can also detect glucose levels in tears — but the researchers say this technology would also have a number of other applications.
To solve
contact lens discomfort issues, Professor Park and his research team have unveiled a new smart
contact lens that uses electrodes made up of highly stretchable and transparent materials.
In addition, during the wireless operations, this smart
contact lens could still maintain the eye temperature stably without abrupt heating.
A team of researchers, affiliated with UNIST has recently introduced a new biosensing
contact lens capable of detecting glucose levels in patients with diabetes.
A great example of pricing strategy being used brilliantly comes out of the Bausch and Lomb
contact lens scandal.
«New smart
contact lens for diabetics introduced.»
Researchers created the glucose sensing
contact lens to demonstrate the versatility of the technology.
Blood testing is the standard option for checking glucose levels, but a new technology could allow non-invasive testing via
a contact lens that samples glucose levels in tears.
This illustration shows the schematic procedure for the fabrication of a surface - enhanced Raman scattering
contact lens via transfer printing.
«Our smart
contact lens provides a platform for wireless, continuous, and noninvasive monitoring of physiological conditions, as well as the detection of biomarkers associated with ocular and other diseases,» says Professor Park.
With a bit of luck, the casual passer - by might not notice the blindfold and think I'm just looking for
a contact lens.
For the procedure, which was first performed in 1995, the team harvested the same limbal stem cells that the cornea uses to fix itself and cultivated them on
contact lens - like sheets.
«This study can be used to diagnose diseases (diabetes and glaucoma) by implementing two types of transparent electronic sensors in the production of smart
contact lens sensors,» said Professor Park.
Moreover, because they lens - shaped firm plastic material, many people complain of comfort issues with
contact lens wear which made wearing them impossible.
«We are now a step closer to the implementation of a fictional idea for a smart
contact lens in the films, like «Minority Report» and «Mission: Impossible.»
But in a study reported in the September issue of Archives of Ophthalmology, only 34 percent of corneal scrapings from
contact lens - wearing keratitis patients allowed researchers to identify the microbes involved.
By age 5, lens reproliferation was 10 times more common with IOLs, occurring in 23 (40 percent) of infants in that group, compared to two infants (4 percent) in
the contact lens group.
In the study, the research team unveiled a smart
contact lens sensor that could help monitor biomarkers for intraocular pressure (IOP), diabetes mellitus, and other health conditions.
By age 5, nine children in
the contact lens group developed minor eye infections that cleared up with antibiotic drops, and in one child, a contact lens broke during wear.
In addition, because the system uses wireless antenna to read sensor information, no separate power source, like battery is required for the smart
contact lens sensors.
«Smart
contact lens sensor» for diabetic and glaucoma diagnosis.»
IOLs can also spare babies — and their parents — the discomfort of daily
contact lens changes, and reduce the risk of introducing germs into the eye.
This complication and others led to the need for one or more additional eye surgeries among 41 (72 percent) of the infants in the IOL group, and 12 (21 percent) in
the contact lens group.
Carol Rosenstiel, O.D., is an optometrist who is the chief of
the contact lens service in the UAB Department of Ophthalmology.
«
The contact lens would feature the customized surface, matching it to the shape of the patient's cornea,» Sun said.
Furthermore, since the electronic sensor is inserted into the soft
contact lens, the feeling of wearing it is also excellent.
«It was observed that the live rabbit did not show any abnormal behavior when wearing
the contact lens sensor,» says Joohee Kim (Combined M.S. / Ph.D. student of Materials Science and Engineering), the first author of the study.
Parviz has yet to combine both the optics and the LEDs in the same
contact lens, but he is confident that even images so close to the eye can be brought into focus.
The powered antenna transmits electricity to
the contact lens, which is used to interrogate the sensors, process the signals and transmit the readings back.
«You won't necessarily have to shift your focus to see the image generated by
the contact lens,» says Parviz.
In 2008, as a proof of concept, Babak Parviz at the University of Washington in Seattle created a prototype
contact lens containing a single red LED.
Last September, Sensimed, a Swiss spin - off from the Swiss Federal Institute of Technology in Lausanne, launched the very first commercial smart
contact lens, designed to improve treatment for people with glaucoma.
But Michael McAlpine at Princeton University and his colleagues have developed a 3D printer that can make a five - layered
contact lens, one which emits light into the wearer's eyes.