Not exact matches
Pollock says that snakes» genomes may be unusually prone to change because they
contain many
repeated sequences that promote misalignment of chromosomes and so make gene duplications more common.
Their simulations confirmed experimental results by other labs that showed the length of
repeating polyglutamine
sequences contained in proteins is critical to the onset of disease.
Now, a team led by University of Pennsylvania physicists has used solid - state nanopores to differentiate single - stranded DNA molecules
containing sequences of a single
repeating base.
The stretch of DNA at the beginning of the HD gene, which
contains the
sequence CAG
repeated many times, and is abnormally long in people who will develop HD
A normal version of the FMR1 gene
sequence, where the fragile X syndrome can develop,
contains 5 - 55 nucleotide (CGG)
repeats.
The direct
repeat regions
contain sequences required for processing pre-crRNA into mature crRNA and tracrRNA binding.
Their genome uniquely
contains a dodecamer
repeat sequence within the NHLRC1 gene, which is prone to expansion.