Sentences with phrase «contained subclones»

Not exact matches

The mammary tumors frequently contained two distinct subclones — one produced Wnt1 while the other did not.

Cancers contain genetically different subpopulations of cells, called subclones.

In all 7 cases, the results suggest a linear model of clonal evolution, in which progression from MDS to sAML was characterized by persistence of a single founder clone (defined by ~ 200 - 700 mutations) and the outgrowth of at least one new subclone which contained dozens or hundreds of additional mutations.

The subclones were tested in normal CM and CM containing 0.5 µg / ml mycophenolic acid for their sensitivity to this drug.

Careful examination of primary breast cancers often reveals multiple genomically distinct subclones that may contain driver alterations that follow spatial patterns of segregation.