Not exact matches
The
zinc finger region, whose structure was discovered by Nobel laureate Aaron Klug, is a
finger - shaped structure
containing a
zinc atom.
The fusion protein bound optimally to a sequence
containing adjacent homeodomain (TAATTA) and
zinc finger (NGGGNG) subsites.
They gave the mice a single injection into the brain,
containing virus particles packed with DNA instructions making the
zinc finger drug.
Both teams»
zinc finger drugs did the job of reducing the activity of genes
containing long CAG stretches.
(17) Arabidopsis
contains three additional members of the
zinc finger family, all predicted to be targeted to organelles.
My research has been about PR Domain
Containing 9 (PRDM9), a multiple
zinc finger protein that mediates the process of meiotic homologous recombination.
It
contains a KRAB motif, a histone H3 Lysine -4-methyltransferase domain, and several
zinc fingers that likely mediate sequence - specific binding to DNA.
The gene product (PHF11)
contains two PHD
zinc fingers and probably regulates transcription.
The octopus genome
contains around 1,800 C2H2
zinc finger transcription factors, the second largest gene family so far discovered in animals (olfactory receptor genes in elephants are the largest at around 2,000).