Sentences with phrase «containing brain slices»

One limitation of the approach presented here is that the aqueous solubility of CM - MK801 (5 — 10 μM) make it less suitable for direct injection into the brain because of the requirement for elevated levels of co-solvents, such as dimethyl sulfoxide (DMSO)(> 0.1 %), which resulted in VTA - containing brain slices that were unsuitable for recordings.

As shown previously in VTA - containing brain slices exposed to cocaine (Argilli et al., 2008), DA neurons showed significantly elevated potentiation of mEPSC amplitudes in PLE − / GFP + DA neurons in the presence of CM - MK801, which further demonstrates the lack of activity for CM - MK801 in PLE − neurons.

Not exact matches

This particular roll of film contains 6000 slices, representing a speck of brain the size of a grain of salt.

The mouse atlas was produced using a method called «in situ hybridisation», in which thin slices of brain tissue are bathed in a solution containing molecular probes that bind to messenger RNA sequences produced by each gene.

Long - term goal of the project will be to visualize and manipulate tau expression also in a systemic context (organotypic slice preparations, mouse brain) by affecting the function of tau mRNA - containing neuronal granules as a potential drug target for the treatment of neurodegenerative diseases.