Sentences with phrase «containing cells from patients»

Scientists could build chips containing cells from patients with specific genetic mutations, which could predict drug responses in specific populations, as well as personalized chips that predict an individual's drug response.

Not exact matches

The catch is that the new cells still contain DNA from the original stem cells, so they don't match the patient's exactly.

Desgrosellier said the team will follow up with mouse models containing tumor fragments from patients to better reflect the diversity of cell types present in human disease.

What could be more «like» a patient's own brain than a miniature one grown from her own cells, and therefore containing DNA identical to hers?

Using specimens collected annually in patients seen at Dr. Young's bone marrow failure clinic at the NIH Clinical Center, the investigators show that patients can support good blood cell production for many years from only a few stem cell clones, which can contain many unfavorable mutations.

To confirm that the missing mutations were important for generating an immune response, the researchers cultured a subset of the neoantigen protein fragments containing the tumor mutations with immune cells taken from three patients» blood samples.

For years, scientists have observed that tumor cells from certain breast cancer patients with aggressive forms of the disease contained low levels of mitochondrial DNA.

It contains data on the electrical properties of about 300 cortical neurons taken from 36 patients and 3D reconstructions of 100 of those cells, plus gene expression data from 16,000 neurons from three other patients.

For example, we can run drug tests on heart cells created from a patient's own skin cells, which contain a complete set of the genes that caused the disease.

Healthy individuals» lungs contain very few goblet cells, but patients who die from asthma — an estimated 5,000 people annually — have significantly higher numbers of these cells.

Importantly, each cell line contained a complete set of the genes from each Huntington's disease patient.

For AQUA analysis, 2 pairs of slides (containing two cores from different areas of each matching primary and metastatic tumor per patient) or test arrays of cores from FFPE placental tissue and MEL624 cells not overexpressing or overexpressing PD - L1 were concomitantly stained.

CD4 + T - cells from patients with HIV - 1 were transduced with a lentiviral vector containing an antisense sequence against the HIV - 1 envelope.

To help tease out cancer's inherited components, the new study adds analysis of the sequencing data from the patients» normal cells that contain the «germline» information.