Sentences with phrase «containing nucleosomes»

Because this region covers the entire CenHs - binding region (around 750 kb), the authors [6] postulated that CenH3 - containing and dimethyl - K9 H3 - containing nucleosomes are interspersed and that the position of these nucleosomes is dynamic, so that a population of cells may have the same DNA sequence interacting with both types of nucleosome.

Nagaki et al. [6] used anti-CenH3 antibodies to immunoprecipitate chromatin (ChIP) comprising DNA bound to CenH3 - containing nucleosomes, confirming that CenH3 is associated with both the CentO repeats and the CRR family of retrotransposons.

Not exact matches

The researchers found that the binding of auranofin takes place through an allosteric, «action - over-a-distance» mechanism within the nucleosome, which is the component that contains the cell's packaged DNA.

Since many of the genes containing «fragile» nucleosomes are controlled in a continuous manner by nutrient availability, modulation of promoter nucleosome stability may be a strategy used to coordinate growth - related transcription on a genome - wide level.

The scientists also found out that the type of promoter containing «fragile» nucleosomes is strongly associated with high levels of transcription.

Although it has not been established that CenH3 alone determines centromere identity, the sequence of a complete centromere should at the least include the entire region that is wound around nucleosomes containing CenH3.

The other type, which contains well - known stable nucleosomes, is located at less frequently expressed genes.

While somatic cells have dense and compacted clutches that contain tens of nucleosomes, clutches in pluripotent cells contain fewer and less compacted nucleosomes.