Sentences with phrase «contaminated lab mice»

Now, immunologists at the National Institute of Diabetes and Digestive and Kidney Diseases in Bethesda, Maryland, have contaminated lab mice in a different way: by giving them gut bacteria from wild mice.

Not exact matches

But when he reexamined those original samples again in the summer of 2011, Silverman discovered that all seven were contaminated, not with mouse DNA but with an infectious molecular clone originally made in his own lab in 2006.

They have since learned that as many as 40 of those lines may never be fully developed; some may even have been contaminated by mouse cells used to sustain them in the lab.

The causes of such unpredictable results, Harris said, can include bad ingredients in the lab, including contaminated and misidentified cell lines; poor research design, including insufficient numbers of mice in animal studies; statistical error and overreach, including «HARKing» (hypothesizing after the results are known), a push beyond the limits of the data; and funding pressures, which can lead scientists to hype or exaggerate their results to remain competitive for additional grant money.

A striking example of this is MPP +, a well - established neurotoxin that specifically attacks the SNc dopaminergic neurons in lab mice, monkeys — and in humans: MPP +'s parent compound, MPTP, has caused numerous cases of Parkinson's - like syndrome in young people exposed to it in underground drug labs, or via contaminated street drugs.1