Not exact matches
The Company's effective income tax rate and comparable effective income tax rate (a non-GAAP measure) from
continuing operations
for the first quarter of 2018
decreased to 29.5 % and 25.6 %, reflecting a lower federal tax rate related to the 2017 Tax Cuts and Jobs Act (Tax Reform).
It
continues, «As more real - world miles accumulate and the software logic accounts
for increasingly rare events, the probability of injury will keep
decreasing.
«Given the
continued progress we've made in
decreasing our delivery times across the board, we are retiring Fastbite in NY and SF to offer even more ways
for more diners to experience their favorite restaurants fast with the new Under 30 Minute option.»
HP (HPQ), along with legacy tech companies like IBM (IBM), has seen its business slump over the past few years as the market
for personal computers
continues to
decrease.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues
for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or
continue to provide, coverage or reimbursement
for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and
decreases in treatment duration; availability of funding
for state AIDS Drug Assistance Programs (ADAPs);
continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications
for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all,
for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that
decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements
for crew members and other employee relation issues; the
continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.
Additional reasons might be given
for The United Methodist Church to rid itself of a commitment to abortion rights: the increasing numbers of African delegates (who are, in the main, pro-life) to General Conference; the horrifyingly high abortion rates (though the annual totals are
continuing to
decrease) in the United States; the pro-life drift of American public opinion (which United Methodism seems to follow); the uncommon clarity of ecumenical teaching on the dignity of the human person; and the providence of God.
8) There is a
continuing decrease in the nurture and emotional support available to couples from their extended family and neighborhoods, and increased searching
for substitute support systems —
for example, in communes, family networks, and group marriages.
In this letter, Luther
continued with his theme of finding employment
for himself elsewhere, a new ministry: «I see that you all grow in spiritual matters, so it seems to me that I should
decrease.»
However, options
for reducing tillage in the mid-Atlantic region have been identified and tried, including: (1) rotating annual grain crops with perennial forages; (2)
decreasing depth and degree of soil inversion (e.g. chisel...
Continued
On - Premise Beverage Alcohol Consumption
Continues to Decline: The on - premise beverage alcohol market was unable to capitalize on an improving economy, as consumption
decreased for the third consecutive year...
Results of the analyses
continue to confirm that all forms of extra support analyzed together showed a
decrease in cessation of «any breastfeeding», which includes partial and exclusive breastfeeding (average risk ratio (RR)
for stopping any breastfeeding before six months 0.91, 95 % confidence interval (CI) 0.88 to 0.95; moderate - quality evidence, 51 studies) and
for stopping breastfeeding before four to six weeks (average RR 0.87, 95 % CI 0.80 to 0.95; moderate - quality evidence, 33 studies).
I want to
continue to breastfeeding as I never produced enough with my first son and only fed
for a few months, having a difficult experience, so weaning is not what I want, but li need to
decrease my supply or I'm going to go crazy!!!!! My breasts are sore all the time!!!
If your supply
continues to
decrease, your baby may start refusing to nurse because he has to work hard
for a small amount of milk.
The recreation bond issue would add $ 63 to the yearly tax bill
for a $ 200,000 house, but the cost can be expected to
decrease as the community
continues to grow, Lewis said.
Cobedding of twins and other infants of multiple gestation is a frequent practice, both in the hospital setting and at home.174 However, the benefits of cobedding twins and higher - order multiples have not been established.175, — , 177 Twins and higher - order multiples are often born prematurely and with low birth weight, so they are at increased risk of SIDS.101, 102 Furthermore, there is increased potential
for overheating and rebreathing while cobedding, and size discordance might increase the risk of accidental suffocation.176 Most cobedded twins are placed on their sides rather than supine.174 Finally, cobedding of twins and higher - order multiples in the hospital setting might encourage parents to
continue this practice at home.176 Because the evidence
for the benefits of cobedding twins and higher - order multiples is not compelling and because of the increased risk of SIDS and suffocation, the AAP believes that it is prudent to provide separate sleep areas
for these infants to
decrease the risk of SIDS and accidental suffocation.
As the primaries
for the Syracuse mayoral race draw closer, the candidate pool
continues to
decrease.
Despite City Hall's efforts, Staten Islanders still
continue to harbor a notorious distaste
for the mayor and his more progressive policies, particularly a 2014 move to
decrease the citywide speed limit.
De Blasio, who has said his administration
continues to put plans in place to
decrease the population in Rikers Island and install several reforms at the jail, said the speaker's plan, first laid out during her State of the City address last week, lacked detail and reasonable options
for housing the approximately 10,000 inmates currently detained at the troubled jail.
Once implemented, the proposal will
decrease wait times
for customers and ease the burden on staff as the demand
for DMV services
continues to grow across the county
As a result of a
decrease in energy costs and weakening of the Canadian dollar, sales tax revenue
continues to decline which creates significant challenges
for the county's budget.
The Legislature has a lot of work to do to capitalize on the 2015 tax
decrease we delivered and to
continue the trend of delivering relief
for taxpayers,» said Chairman Mills.
The New York State Department of Community and Correctional Supervision has claimed that as crime rates decline and inmate populations
decrease, taxpayers can not afford to
continue paying
for empty prison beds.
Under provisions of the current
continuing resolution, federal research funding would total $ 55.2 billion
for FY 2007, a 2.6 percent
decrease that would mark the first year - to - year decline in at least three decades.
The findings suggest that as the U.S. energy market
continues to shift from coal to natural gas, the overall «toxicity burden» of the electricity sector will
decrease, said study corresponding author Shelie Miller, an environmental engineer and an associate professor at the U-M School
for Environment and Sustainability's Center
for Sustainable Systems.
«These findings suggest that while pentaBDE levels have been
decreasing since the phase - out, they
continue to be detected in the blood of young children nearly 10 years following their removal from U.S. commerce,» says first author Whitney Cowell, PhD, pediatric environmental health research fellow at Mt. Sinai and former doctoral student from the Columbia Center
for Children's Environmental Health.
Overall, 75 percent think discrimination against women has
decreased over the past 25 years or so, but at the same time an equal number of Americans say discrimination
continues to be an issue today
for many women.
In a study of 81 overweight and obese women with type 2 diabetes who usually consumed diet beverages and were on a weight loss program, those who substituted water
for diet beverages after their lunch
for 24 weeks had a greater
decrease in weight -LRB--6.40 vs. -5.25 kg) and body mass index -LRB--2.49 vs. -2.06 kg / m2) compared with those who
continued to consume diet beverages.
Climate change models predict that the Arctic sea ice will
continue to shrink in a warming world (as much as 40 % of the ice is expected to be gone by midcentury), and the resulting changes — including later formation of ice in the autumn, rain falling on the snow, and
decreasing snow depths — will make it increasingly difficult
for the seals to construct their snow caves, NOAA says.
While second - stage results showed no significant differences between participants
continuing to receive weekly doses of the active drug, those receiving biweekly doses and those shifted to placebo, Kimball notes that, since it is typical
for the severity of HS symptoms to increase and
decrease and because the study protocol required treatment discontinuation
for participants whose symptoms stopped responding to the drug, larger scale studies will be required to better define the ideal length and frequency of treatment.
As cropland
continues to expand at the expense of Cerrado vegetation, the
decrease in dry season water recycling could eventually impact the region's critical rainy season, which is responsible
for the lion's share of Cerrado rains.
«
Continued participation
for patients not finding success in an ILI program alone may lead to frustration and
decreased interest in future weight control efforts.»
We have observed on several occasions that,
for the majority of endothelial cell lines, the transfer to 37 °C conditions
for 72 h correlated with a 50 % reduction in cell proliferation, a value that
continued to
decrease with time.
For example, if deforestation
continues in the Central and South American tropics at the current rate, the number of fragments will increase 33-fold and their mean size will
decrease from 17 ha to 0.25 ha.
Overall cancer death rates
continue to
decrease in men, women, and children
for all major racial and ethnic groups.
Death rates
for each major category of childhood cancer,
for example,
decreased by about half since 1970 and
continue to drop, but since fewer than one - third of 1 percent of cancer deaths occur in children younger than age 15, even the complete elimination of childhood cancer deaths would have little impact on overall cancer mortality.
According to a new study in JAMA Neurology, U.S. military service members who endured a mild concussion after blast injury while deployed in Iraq or Afghanistan may
continue to experience mental health symptoms as well as
decreases in quality of life
for at least five years after their injury.
[5] As RT delivery methods
continue to improve and RT use
for this disease
decreases, it is our hope that the incidence of RT - associated breast cancer following curative treatment
for Hodgkin lymphoma will decline.
Please
continue reading because there is something out there that
decreases appetite, takes away craving
for sweets, bad carbohydrates and gets rid of sugar spikes which then allows your brain / body to look
for healthy food when one becomes hungry NOT JUNK FOOD.
As you
continue on, you will find your fitness level increases and the rest times required
decrease significantly until you're able to work out
for a longer period of time.
In 2005, Browns Mill School became the first sugar - free school in the country, and the results speak
for themselves with a 30 percent
decrease in nurse visits, a 28 percent drop in teacher referrals
for bad behavior, and improved test scores.20 Dr. Sanders - Butler
continues to see the difference in the children's health through weight loss and fewer absences, as well as more frequent everyday positive interactions with happier children.
If you get side effects while increasing the dose, you should slightly
decrease it, and
continue with it
for the rest of the cure.
The 15 seconds is enough time
for the lactic acid that we just built up to
decrease enough
for us to
continue on with the movement.
I am sooooo thankful to say, I have been using organic coconut oil
for several years... My thyroid meds
continue to be
decreased, and I no longer have to take any allergy meds besides shots.
Bake the meatballs at 450 °F
for 10 minutes and then
decrease the oven temperature to 350 °F and
continue cooking
for another 8 minutes, or until they start to turn golden brown.
For most men, testosterone levels start
decreasing around age 40 and
continue to
decrease about 1 % each year.
If you
continue to train with dysfunctional movement (i.e. weakness, imbalances, mobility issues, etc.), you will be training in a dysfunctional manner, which will put you at risk
for injury and
decrease your ability to workout to you highest potential.
In a 10 - week study done on alternate day fasting
for weight loss, it was found that after 2 weeks, the hunger response
decreased significantly and
continued to stay low (2).
Burst exercise improves blood pressure, insulin sensitivity, cholesterol profiles, cardiovascular health, and
decreases abdominal fat and body weight (while maintaining muscle mass).2 «The Basics of High Intensity Interval Training,» The American College of Sports Medicine, accessed Feb 8, 2016,...
continue 3 «Rev Up Your Workout With Interval Training,» Mayo Clinic, accessed Feb 8, 2016,...
continue All things that we love
for our bodies.
Researchers have found that BDNF levels decline progressively with age.10 Lommatzsch, M., et al. «The Impact of Age, Weight and Gender on BDNF Levels in Human Platelets and Plasma,» Neurobiology of Aging 26 (2005):...
continue At the same time that BDNF levels
decrease, the volume of the hippocampus (primary center
for emotion and memory) also
decreases.11 Erickson, K.L., et al. «Brain - Derived Neurotrophic Factor is Associated with Age - Related Decline in Hippocampal Volume, Journal of Neuroscience 30,...
continue In fact, in some neurological diseases, such as Huntington's and Alzheimer's disease, BDNF levels are low or deficient.12 Laske, C., et al. «
Decreased Brain - Derived Neurotrophic Factor (BDNF) and B - Thromboglobulin Blood Levels in Alzheimer's Disease,» Journal of...
continue