Sentences with phrase «control angiogenesis»
«Finding a way to control angiogenesis not only provides a target for the development of anti-cancer therapies, but may also prove useful in similarly starving abnormal blood vessel growth elsewhere in the body, like in diabetic eye disease.»
https://www.sciencedaily.com/
They focused towards this end on the vascular growth factor Angiopoietin - 2, which is produced by endothelial cells and does not just control angiogenesis, but acts as a key responsiveness factor for endothelial cells.
The orphan receptor Tie1 controls angiogenesis and vascular remodeling by differentially regulating Tie2 in tip and stalk cells.
Pericyte - expressed Tie2 controls angiogenesis and vessel maturation.
Not exact matches
«What's more, the cancer - related proteins were using first neighbours to interact with the pathways controlling important processes for carcinogenesis, such as angiogenesis, autophagy and DNA repair.
These analyses showed that Angiopoietin - 2 is not just affecting angiogenesis, but controls at the same time the production of tumor promoting growth factors in endothelial cells.
The formation of this network is controlled by a process called angiogenesis.
In the past 10 years our laboratory has investigated the role of cell - matrix interaction in the control of endothelial cell functions in vivo and in vitro and provide the first evidence that the collagen binding integrin alpha1beta1 is pro-angiogenic and pro-tumorigenic and its inhibition and / or down - regulation is beneficial in the setting of tumor associated angiogenesis.
Cellular, biochemical and genetic experiments collectively establish a role of pericyte - expressed Tie2 in the control of angiogenesis and vascular maturation.
EC - and MPC - derived Apelin, Oncostatin - M and Periostin controlled myogenesis / angiogenesis coupling and were required for myogenesis and vessel formation.
Research Interests: angiogenesis; atherosclerosis; cell migration; endothelial cells; iron metabolism; macrophages; translational control
We use the Haplobank in reverse genetic screens to investigate the temporal resolution of essential genes in mES cells, and to identify novel genes that control sprouting angiogenesis and lineage specification of blood vessels.