Prominent among these were promoters affecting pathways that
control cell adhesion and axon guidance.
Not exact matches
«Inflammatory arthritis is caused when immune
cells are recruited from the blood into the joint in a highly regulated process
controlled by chemoattractants and
adhesion receptors,» says Andrew Luster, MD, PhD, chief of the MGH Division of Rheumatology, Allergy and Immunology, director of the CIID and senior author of the report.
Thus, the vertical force and moving speed of the AFM cantilever (0.06 N / m in vertical spring constant) was
controlled at a vertical force of 5 nN at an indentation speed of 0.1 µm / s to guarantee the rupture of the filament and to partially dissect
cell adhesion structures between two neighboring
cells.
Dynamic regulation of ROCK in tumor
cells controls CXCR4 - driven
adhesion events.
Furthermore, Eph signalling in mural
cells has been shown to
control cell motility and
adhesion as well as pericyte - EC assembly33, 34.
The work has led him to explore the role of protein phosphorylation in a diverse array of cellular functions, including transformation,
cell communication,
cell adhesion,
cell - cycle regulation, the
control of gene expression, and protein degradation.
FAK promotes recruitment of talin to nascent
adhesions to
control cell motility.
Siah regulation of Pard3A
controls neuronal
cell adhesion during germinal zone exit.
The alpha actinin (ACTN) family proteins are actin - binding proteins that regulate cytokinesis,
cell adhesion, spreading, migration and signaling to
control cell function.
Vascular Signaling Regulation of vascular morphogenesis Brant Weinstein, NICHD / NIH Hemodynamic
control of vascular development Mark Kahn, University of Pennsylvania A rap song about vascular
cell adhesion Mark Ginsberg, University of California, San Diego
The laboratory currently pursues four integrated research objectives: 1) Defining how dynamic regulation of
adhesion and migration
controls metastasis, 2) Identification and characterization of the metastatic
cell populations within a primary tumor, 3) Experimental modeling of metastasis in a clinically relevant manner, and 4) clinical implementation of molecular markers of migration as biomarkers of tumor progression and metastasis.
Specific mechanistic studies include an interrogation of the
adhesion dynamics
controlled by the tetraspanin CD151 and affiliated
adhesion receptors (Integrins and IgG
cell adhesion receptors).
The origins of many of these and other genes specific to animal processes such as
cell adhesion, and social
control of
cell proliferation, death and differentiation can be traced to genomic events (gene birth, subfamily expansions, intron gain / loss, and so on) that occurred in the lineage that led to the metazoan ancestor, after animals diverged from their unicellular «cousins».
MAP3K8
controls cancer
cell proliferation and migration by regulating key players in G1 / S transition and
adhesion dynamics.
This diverse «toolkit» of genes correlates with critical aspects of all metazoan body plans, and comprises
cell cycle
control and growth, development, somatic - and germ -
cell specification,
cell adhesion, innate immunity and allorecognition.
At the 8 -
cell stage, compaction is a developmentally -
controlled cell -
cell adhesion process that rounds up the embryo.
W. E. Reintsch, A. Habring - Mueller, R. W. Wang, A. Schohl, F. Fagotto, beta - Catenin
controls cell sorting at the notochord - somite boundary independently of cadherin - mediated
adhesion.