Sentences with phrase «control cell fate»
Her goals are to continue working to understand how the dynamics of p53 and other signaling pathways important in cancer control cell fate decisions.
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Our work focuses on discovering and characterizing novel small molecules that can control cell fate and function in numerous cell types, including stem cell maintenance, activation, differentiation, and reprogramming in various developmental stages and tissues.
«In the cell, noise is constantly «jiggling the handle» that controls cell fate decisions, and this causes some cells — randomly — to switch fates,» he said.
Agilent Seahorse XF technology is enabling the shift to real - time quantification of immune cell function, opening a new window on controlling cell fate.
Not exact matches
Researchers from the Department of Biomedicine at the University of Basel have now found that the fate of adult hippocampal stem cells is not only controlled by their local niche, but also by a cell - intrinsic mechanism.
«Neural stem cells control their own fate.»
This is what makes the matter particularly exciting for the scientists, because «this control centre decides about the fate of differentiating cells and thus about the fate of the root architecture.»
The article «EGFR signalling controls cellular fate and pancreatic organogenesis by regulating apicobasal polarity» has been published in Nature Cell Biology.
Every cell in the body uses phosphorylation, the process of adding a chemical tag to control a protein's function and fate, such as when it moves from one part of a cell to another or binds to other proteins.
This study provides experimental evidence which shows the important role of RNA levels in the controlling the fate of embryonic stem cells, and shows an understanding of RNA's ability to differentiate stem cells at the molecular level.
Because of the consistency among many cells, they concluded that TCF - 1 control of T - cell fate is fundamentally important in determining what a cell will become.
The Hippo pathway not only defines final tissue size by controlling developmental growth, but is also key to specifying stem cell identity and proliferation, to regeneration and tissue repair, as well as numerous cell fate decisions.
His work has focused on discovering and characterizing novel small molecules that can control various cell fates and functions, including stem cell maintenance, activation, differentiation and reprogramming in various developmental stages and tissues.
Dietmar J. Kappes discovers a mouse with a mutation in a master regulator gene controlling T cell fate.
Just a few kinds of signals control the fates of cells that either maintain their stem cell state, divide or differentiate in a developing organism.
Our current works have focused on screening the chemical libraries to identify and further characterize small molecules that can control stem cell fate in various systems.
Her group is particularly interested in the cellular and molecular mechanisms which control lung epithelial stem cell fate decisions.
He is interested in the molecular control of stem and progenitor cell fate decisions.
Spatial control of adult stem cell fate using nanotopographic cues.
Our overall goals are to decipher and manipulate mechanisms that control the fate of retinal cells throughout their life.
The question of how cellular behavior is controlled is at the center of stem cell biology, and understanding the mechanisms of cell fate regulation is key for treating diseases that occur upon dysregulation, such as cancer or diabetes.
Research in his Laboratory of Stem Cell Bioengineering (LSCB) is at the interface of stem cell biology and biomolecular engineering to gain fundamental insight into how protein components of niches control the fate of adult stem ceCell Bioengineering (LSCB) is at the interface of stem cell biology and biomolecular engineering to gain fundamental insight into how protein components of niches control the fate of adult stem cecell biology and biomolecular engineering to gain fundamental insight into how protein components of niches control the fate of adult stem cells.
He is internationally recognized for his work on the control of cell growth and fate by the TGF -(beta) family of growth factors.
The latest findings reported by researchers at La Jolla Institute for Allergy and Immunology illustrate just how important TET proteins are in controlling cell proliferation and cell fate.
The Wnt target gene encoding the transcription factor Achaete scute - like 2 controls the fate of the intestinal stem cell (26).
Metabolic control of primed human pluripotent stem cell fate and function by the miR - 200c - SIRT2 axis.
He was also the first to describe the role of tiny molecules in the heart — called microRNAs — which carefully titrate levels of gene activity to control the fate of cells.
Research Interests: Molecular control of cell fate from stemness to differentiated skeletal and neuronal cell types; SOX transcription factors; skeletal malformation and degeneration diseases; intellectual disability and autism spectrum disorders; mouse genetic models; human pluripotent stem cell differentiation models in vitro
The events of this title follow those of Fate / EXTRA, in which the world of SE.RA.PH is controlled by the all - powerful lunar super-computer known as the Moon Cell Automaton.