Not exact matches
Significant inverse association between
coffee consumption and liver cancer risk seen in both case -
control and cohort studies (after adjustment for existing liver disease)
Tang et al (2010) evaluated 5 prospective cohorts and 8 case -
control studies and found that overall those with the highest levels of
coffee consumption had a 27 percent higher risk for lung cancer compared to never drinkers or those with least
consumption.
Using both prospective cohort and case -
control studies, Turati (2011) found that
coffee consumption was not associated with risk of pancreatic cancer.
After
controlling for blood levels of SHBG, the reduction in risk linked to
coffee consumption wasn't significant.
Higher
coffee consumption is also associated with a significantly lower incidence of Parkinson's disease, 13 and caffeine may help
control movement in those with Parkinson's disease, according to more recent research.14 Liver cancer and liver disease are also inversely associated with
coffee consumption.
However, a 2013 meta - analysis of 6 prospective and 6 case
control studies provided insufficient evidence that
coffee consumption significantly increases hip fracture risk.
Coffee consumption and serum lipids: a meta - analysis of randomized
controlled clinical trials.
Research also suggests that
coffee consumption does not worsen symptoms in those who suffer these conditions when confounding factors, such as BMI and smoking status, are
controlled for2, 8,10, 13.
Maternal
consumption of
coffee and tea during pregnancy and risk of childhood ALL: a pooled analysis from the childhood Leukemia International Consortium, Cancer Causes and
Control, published online.
In an earlier article from the Honolulu Heart Program, based on 58 cases also included in the case panel presented here, Grandinetti and colleagues5 reported that
coffee drinking was inversely related to PD, although the association was not statistically significant after
controlling for cigarette smoking and alcohol
consumption.
Interactions of
coffee consumption and postmenopausal hormone use in relation to breast cancer risk in UK Biobank, Cancer Causes and
Control, published online.
Effects of
Coffee Consumption on Fasting Blood Glucose and Insulin Concentrations Randomized
controlled trials in healthy volunteers Rob M. van Dam, PHD1, Wilrike J. Pasman, PHD2 and Petra Verhoef, PHD34http: / / care.diabetesjournals.org/content/27/12/2990.
After
controlling for caffeinated
coffee and other covariates, compared with women with the lowest
consumption of decaffeinated
coffee (≤ 1 cup per week), the risk of depression was increased for higher
consumption, with the exception of the very highest
consumption category (≥ 2 cups per day).
Fig 9
Coffee consumption in randomised
controlled trials86 and change (mean difference) in birth weight
Fig 7
Coffee consumption in randomised
controlled trials36 and change (mean difference) in cholesterol concentration.
A meta - analysis of 9 cohort and 9 case -
control studies found a borderline significant influence of highest
coffee consumption on the risk of breast cancer.