Sentences with phrase «control factors involved»

Not exact matches

But the Cambridge Analytica crisis strikes at the heart of Facebook's data - mining business model and involves factors not entirely under his control, limiting the value of his past experience at damage control.
You have the option to customize many of your settings which allows you to have control over factors such as the type of trade and the risk factors involved.
Let's face it: We are unlikely to find a single party that truly represents a «culture of life,» and abortion will probably never be made illegal, so we'll have to go about it the old fashioned way, working through the diverse channels of the Kingdom to adopt and support responsible adoption, welcome single moms into our homes and churches, reach out to the lonely and disenfranchised, address the socioeconomic issues involved, and engage in some difficult conversations about the many factors that contribute to the abortion rate in this country, (especially birth control).
Well, there are a number of factors involved in this process, including: fertilizing, weed control, flowering and pollination, fruiting, and avoiding reaching the fruit load.
Their are so many factors involved that I believe the money should be spent on helping at risk families get and or stay on their feet, but out right trying to control the way society as a whole raises babies is not appropriate.
After controlling for factors known to influence brain volume and cognitive test scores, such as age and gender, the researchers found that a higher self - reported frequency of game playing was significantly associated with greater brain volume in several regions involved in Alzheimer's disease (such as the hippocampus) and with higher cognitive test scores on memory and executive function.
SU101 targets the signal transduction activated by a messenger called platelet - derived growth factor, which controls the genes involved in tissue formation and wound healing.
But if the factors involved in this quality - control system were absent, damaged mRNA accumulated in the cell, just as it does in Alzheimer's.
Among the issues to be resolved there would be, for example, how to identify the environmental factors that control the production of aggressive morphs; what costs and benefits interaction involves for each participant; the taxonomic status of the deceit and the variability level in the chemical signal used for misleading ants; or what happens with related aphid species which also relate with ants.
«Discovering the factors involved in granuloma control vs those not able to control bacterial growth is a critical step in potentially developing treatments that could «freeze» granulomas into a protective state in the two billion latent carriers,» explains Grace Peng, Ph.D., Director of the NIBIB program for Mathematical Modeling, Simulation and Analysis.
A new study involving roundworms appears to have isolated one gene — a transcriptional factor (or gene that controls the regulation of other genes in the genome)-- that appears to be an essential member of the pathway that translates reduced caloric intake into a longer life span.
Many factors are involved in controlling which genes get transcribed into messenger RNA and when, but RNA binding proteins interact with the messenger RNA itself to regulate gene expression after transcription has occurred.
Several research groups are pursuing gene therapy approaches to regenerate skin, such as using genes to control expression of growth factors involved in skin healing.
The expression of mRNA for factors involved in promoting mitochondrial biogenesis, including the transcription factor Ppard, the PPARδ coactivator Pgc - 1α, and citrate synthase was greater in gastrocnemius muscles from IL - 15Rα — KO relative to B6129 control (Figure 5C); however, levels of these genes were unchanged in spleen and kidney (data not shown).
«We have identified the genes and growth factors involved and, thanks to a collaboration with Microsoft Research, we can now computationally model the control circuitry in mouse cells.
We want to understand how different RFX transcription factors are required for ciliogenesis control and how they are involved in ciliary specialization in mouse tissues.
Researchers have identified a host of factors involved in epigenetic control of gene expression and development, but many of the precise mechanisms underlying this type of regulation remain unclear.
This is in accordance with previous reports that decitabine and 5 - azacytidine produce a marked synergistic effect in combination with suberoylanilide hydroxamic acid and romidepsin in T - lymphoma cell lines by modulating cell cycle arrest and apoptosis.26, 27 As a mechanism of action, KMT2D mutations of B - lymphoma cells promote malignant outgrowth by perturbing methylation of H3K4 that affect the JAK - STAT, Toll - like receptor, or B - cell receptor pathway.28, 29 Here our study indicated that dual treatment with chidamide and decitabine enhanced the interaction of KMT2D with the transcription factor PU.1, thereby inactivating the H3K4me - associated signaling pathway MAPK, which is constitutively activated in T - cell lymphoma.13, 30,31 The transcription factor PU.1 is involved in the development of all hematopoietic lineages32 and regulates lymphoid cell growth and transformation.33 Aberrant PU.1 expression promotes acute myeloid leukemia and is related to the pathogenesis of multiple myeloma via the MAPK pathway.34, 35 On the other hand, PU.1 is also shown to interact with chromatin remodeler and DNA methyltransferease to control hematopoiesis and suppress leukemia.36 Our data thus suggested that the combined action of chidamide and decitabine may interfere with the differentiation and / or viability of PTCL - NOS through a PU.1 - dependent gene expression program.
Once again, the genes that are subject to HAR2 regulation are still unclear, although GBX2, a transcription factor that controls proper expression of genes involved in embryo morphogenesis, is one promising candidate.
Joslin scientists are actively involved in studying the regulation of the many factors that control the storage, mobilization and utilization of excess energy in adipocytes (fat cells).
ApoE as a major causative factor and therapeutic target in Alzheimer's disease and other neurodegenerative disorders; small - molecule structure correctors to convert apoE4 to apoE3 and reverse the detrimental effects of apoE4 on mitochondria and the cytoskeleton; small - molecule protease inhibitors to block the formation of toxic fragments of apoE4; Plasma lipoprotein metabolism regulation involving apoE and apoB; cholesterol homeostasis modulation by lipoprotein receptors controlling lipoprotein clearance by the liver; Plasma HDL cholesterol (HDL - C) metabolism in the progression of atherosclerosis; the genetic epidemiology of the metabolic syndrome and low HDL - C levels established by the Turkish Heart Study.
While it is possible to induce atherosclerosis in some mice, it is important to realize that the presence of cholic acid can influence transcription factors controlling genes involved with regulating lipoprotein metabolism and inflammation, both of which are important in the development of atherosclerosis (16, 17), and can also promote gallstones in certain mouse strains (18, 19).
«It's important to counsel couples regarding the risk of conception [with] in vitro, but, controlling for all confounding factors, there's not really an increased risk for babies conceived with IVF,» says George R. Attia, M.D., director of reproductive endocrinology and infertility at the University of Miami Miller School of Medicine, who was not involved in the study.
The other major factor involved in ridding your fibromyalgia symptoms and taking back control of your health and your life is through your body's unique biochemistry, which we will be doing throughout, and using food and holistically balanced nutrition as our main weapons that will start winning back your confidence and your equilibrium starting from day one.
Although parents can't control those factors directly, we can help by staying informed and involved in the systems that influence our children's school experiences, from voting for local school councils to being aware of national education policy.
What were external factors (environment) involved that Zsolt has no control over?»
Of these studies, the one by Nye, Konstantopoulos, and Hedges is the most compelling because it involved random assignment of students to classes controlled for factors such as the previous achievement of students, socioeconomic status, ethnicity, gender, class size, and whether or not an aide was present in class.
Dr Michiel van Ratingen says: «Lane departure is a factor in a large proportion of accidents, often involving loss of control and resulting in fatal and serious injuries.
Determining your auto insurance rates involves many different factors, including your age, gender, and accident history — but most of those, you can't control.
Between the vacuum and electronic controls of an automatic, along with the stall speed of the torque converter, modifying the engine has extra factors in it when there's an automatic involved.
There is a lot of truth there, because the alchemy involves the book itself combined with many factors out of our control.
But the Fed has very little control over real interest rates, and it's not at all clear how low short - term rates fed into low long - term rates, as many other factors were involved.
You have the option to customize many of your settings which allows you to have control over factors such as the type of trade and the risk factors involved.
Dog - bite - related cases have been the subject of many studies which say that most of the involved factors are under the control of the person who owns the dog (source: Co-occurrence of potentially preventable factors in 256 dog bite - related fatalities in the United States).
Other biological variables involve factors that can be controlled when drawing the blood sample, such as ensuring the animal is properly fasted.
hmm thats a tough one, thats hard for me to choose, there are so many different factors involved in making a game great — graphics, game play, music, controls and with new games coming out all the time with better graphics etc its difficult.
Given the large number of varying factors involved in controlling the path of «weather» (in n - dimensional phenomenistic space), it seems very likely that even major effects shouldn't be expected to repeat themselves.
I have too much respect for Allison to get into a spitting match with him over something that there is simply too little data to positively determine, too much corruption and money involved for those who support that mankind can affect and control global weather to any significant amount all while ignoring so many other factors such as solar winds, Sun spot activity and even the amount of water vapor in the atmosphere, which is never a part of any of the seriously flawed climate models.
Whether that involves making the most of lesser regulatory control, or developing new areas to take into account environmental factors and commodity pricing issues, we'll just have to watch how it all plays out.
However, ResumetoInterviews.com do not guarantee that desired interviews nor jobs will be secured as a result of a resume or CV alone; there are far too many determinant factors involved throughout the job search process that are beyond ResumetoInterviews.com's control as a writer, and ResumetoInterviews.com will not be held accountable for neither a customer's lack of qualifications nor ineffective job search efforts.
As mentioned below, under «Product Guarantees», we do not guarantee that desired interviews nor jobs will be secured as a result of a resume alone; there are far too many determinant factors involved throughout the job search process that are beyond our control as resume writers, and we will be held accountable for neither a customer's lack of qualifications nor ineffective job search efforts.
Our study indicates that this reduced internal health control is one of the psychosocial factors that is involved in the CFS symptom complex, either as a predisposing or maintaining factor or both.
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