Familiality and Heritability of Binge Eating Disorder: Results of a Case -
Control Family Study and...
Method: We used a new ACE structural equation model to estimate heritability from a case -
control family study of BED conducted in the Boston area.
In the case -
control family study, BED was found to aggregate in families, and heritability was estimated as 57 % (CI: 30 - 77 %).
Not exact matches
The
study compared the compound annual growth rate of a
Family Index of 23 companies — in which at least 30 % of voting control belonged to a family with multi-generational involvement in the ownership or management — against 412 widely held firms over a 15 - year period (1998 to
Family Index of 23 companies — in which at least 30 % of voting
control belonged to a
family with multi-generational involvement in the ownership or management — against 412 widely held firms over a 15 - year period (1998 to
family with multi-generational involvement in the ownership or management — against 412 widely held firms over a 15 - year period (1998 to 2012).
Still, the CCBE
study indicates dual - class structures may actually contribute to the outperformance of
family -
controlled firms.
Insiders at
family -
controlled firms attribute their superior performance to a difference in priorities, says Matt Fullbrook, manager of the CCBE and co-author of the
study.
A recent
study published in the American Sociological Review clearly showed that, in a white collar environment, allowing workers some
control over their own schedules, including being able to work from home, had a positive effect on employees» work -
family balance without sacrificing productivity.
Although billions of dollars are being expended annually on
family planning services in less - developed countries, and such programs have been promoted by various governments at the national level for four decades, there are only a few
studies that have attempted to measure the demographic and health impact of
family planning against a «
control group» — a similar area which lacks the service.
As a result of this all too typical pattern of unjust land distribution, for example, 77 percent of the land in El Salvador, where fourteen
families control the wealth, is suffering from erosion, according to a recent
study.25 A more just distribution of land would greatly reduce the negative impact on the environment.
The document was the final report of a theological commission established in 1966 by the archbishop of Cracow, Karol Wojtyla, to help him in his work on the Papal Commission for the
Study of Problems of the
Family, Population, and Birth Rate, inevitably dubbed the «Birth
Control Commission» by the world media.
The Nurse -
Family Partnership has been
studied in three separate randomized
controlled trials, which have shown positive effects on the mothers, including reduced incidence of child abuse, arrest, and welfare enrollment.
In 2007, researchers published the first randomized,
controlled study of the effect of being raised in an orphanage; that
study, and subsequent research on the same sample of Romanian orphans, found that compared with babies placed with a foster
family, those who were sent to institutions had lower IQs, slower physical growth, problems with human attachment and differences in functioning in brain areas related to emotional development.
ACEs usually refers to the 10 types of childhood adversity that were measured in the U.S. Centers for Disease
Control and Prevention's Adverse Childhood Experiences (ACE)
Study: physical abuse, emotional abuse, sexual abuse, physical neglect, emotional neglect, a
family member who's an alcoholic or addicted to other drugs, a
family member diagnosed with a mental illness, witnessing a mother being abused, a
family member in prison, and loss of a parent through separation or divorce.
My plan was to graduate, do my post-grad
study and then go on to counsel
families who've suffered a traumatic birth experience, and raise awareness for post-natal PTSD and other mental health conditions which are exacerbated by the feeling of loss of
control during labour.
The second most common style (13 parents from 7
families), the
study found, was
controlling, a parenting style in which parents:
These patterns remained, Dr. Cook describes, «even after the
study had
controlled for many features of the children's
families and the quality and type of daycare that the children had experienced.»
Limitations of the
study included low response rate for
control families, higher socioeconomic status in participants vs. nonparticipants, possible residual confounding despite multivariate analysis, and possible recall bias because of retrospective design.
In a case -
control study, researchers identify a group of cases (here, the babies who died of SIDS) and compare them to a
control group of babies /
families with similar characteristics to find out what could account for differences in outcomes (one group died from SIDS; one did not).
Research shows that
families typically receive roughly half of the number of home visits expected.16, 17 For example, across three randomized
controlled trials conducted of Nurse
Family Partnership, average dosage of visits ranged from 45 to 62 percent.18 Research also shows that many, perhaps most,
families enrolled in home visiting programs drop out before their eligibility ends.16, 19,20 Some home visiting
studies have varied the dosage that
families were offered and found that fewer home visits produced outcomes similar to higher levels of exposure.21
Studies of the Nurse
Family Partnership model followed children to 6 years and found significant program effects on language and cognitive functioning as well as fewer behaviour problems in a randomized
controlled trial
study.24 In addition, more recent evaluations of Healthy
Families America have shown small, but favourable effects on young children's development.25, 26
One randomized
controlled trial comparing home - visited
families with
control participants who received other community services found a statistically significant difference in mean depressive symptoms at two years post-enrollment, but this contrast was nonsignificant at three years post - enrollment.15 A second
study of Early Head Start found no differences in depressive symptoms between intervention and
control group participants post-intervention, although a difference was detected at a longer - term follow - up prior to children's enrollment in kindergarten.10 Other randomized
controlled trial
studies have not found effects of home visitation on maternal depressive symptoms.12, 16,17
Subsequent prospective
studies yielded similar results, whether they
controlled for parental age, child age, race and
family structure; 12 poverty, child age, emotional support, cognitive stimulation, sex, race and the interactions among these variables; 13 or other factors.14 — 17 These
studies provide the strongest evidence available that physical punishment is a risk factor for child aggression and antisocial behaviour.
This is consistent with other
studies demonstrating a link between breastfeeding and maternal sensitivity.25, 26,27 For example, in a longitudinal
study of more than 1300
families in the USA, mothers who breast fed were observed to be more sensitive to their babies at 6, 15, 24 and 36 months.27 Importantly, this difference persisted after statistical
control for the effects of maternal mental health, the quality of the home environment in terms of infant health and stimulation and socioeconomic status.
«The population growth is affecting the infrastructure, sectors and the environments, but it has been established by
study that «if they plan the
family very well, it can curb or
control the growth of the population and we can reduce Nigeria's population,» Fayehun said.
Choi, Christine Lippard, an assistant professor of human development and
family studies at Iowa State; and Shinyoung Jeon, a postdoctoral research fellow at the University of Oklahoma - Tulsa, analyzed data measuring inhibitory
control (the ability to pay attention and
control natural, but unnecessary thoughts or behaviors) and math achievement for low - income students in Head Start through kindergarten.
«When mothers are highly
controlling of small children's play, those children are less likely to want to engage with them,» said Jean Ispa, co-chair of the MU Department of Human Development and
Family Studies and a professor in the College of Human Environmental Sciences.
A second, genome - wide association
study scanned the genome for common variants behind autism in more than 10,000 affected children, their
families, and
controls.
Supported by the São Paulo Research Foundation — FAPESP under the aegis of its Research Program on Biodiversity Characterization, Conservation, Restoration & Sustainable Use (BIOTA - FAPESP, the
study relied on the collaboration of the City's Animal Health
Control Center and its Department of Parks & Green Areas to carry out a collection of 37,972 specimens of the
family Culicidae (which gathers flies commonly known as mosquitoes) from nine municipal parks — later laboratory analysis would show that these mosquitoes belonged to 73 species and 14 genera.
Anderson said the
study took this into account by
controlling for where people live, along with income, age, education, gender and
family size.
«Although this wasn't an experiment, it was a well -
controlled longitudinal
study in a racially diverse sample — so it provides a strong clue that being socially integrated early in life is good for our health independent of a number of other factors such as personality, weight in childhood, and the
family's social status in childhood,» she explains.
«If we find that we are able to reduce the recurrence rate of autism within
families substantially enough, others will want to
study this in larger groups with larger
controls.»
A related
study, also published in PLOS Genetics, shows that RPM - 1 functions as a part of a novel pathway to
control β - catenin activity — this is the first evidence that RPM - 1 works in connection with extracellular signals, such as a
family of protein growth factors known as Wnts, and is part of larger signaling networks that regulate development.
In their
study, the researchers randomized 22 urban elementary schools serving low - income
families to either the INSIGHTS intervention or a supplemental reading program, which served as a
control condition.
«The ability to
control the functional states of opioid receptors is of particular interest because they belong to the large
family of so - called G - protein - coupled transmembrane receptors (GPCRs), which make up a large fraction of the proteins targeted by pharmaceutical agents,» says Matthias Schönberger, first author of the new
study.
Although numerous
studies have examined the potentially detrimental effects of restrictive feeding practices on children, the current
study was novel in that it focused on the interplay of the parent's emotions with their
controlling the child's food intake, said lead author Jaclyn A. Saltzman, a doctoral researcher in human development and
family studies and scholar in the Illinois Transdisciplinary Obesity Prevention Program.
The Finnish team
studied 21
families with a history of MS, as well as other MS patients and healthy
controls.
In this
study, the research group has found that a peptide called EPIDERMAL PATTERNING FACTOR - LIKE 2 (EPFL2) and its receptor protein, ERECTA
family receptor kinases,
control the amount of auxin during leaf tooth growth.
In work published in August in the Proceedings of the National Academy of Sciences and presented today, researchers from the Hospital for Sick Children in Toronto, Canada,
studied 11
families with Li - Fraumeni syndrome and reported that those affected had an average of 12 CNVs in their genome, compared with three in
controls.
A
study of the development of the nervous system of the nematode Caenorhabditis elegans by Neda Masoudi, Oliver Hobert and colleagues reveals a novel function for a member of the basic helix - loop - helix
family of transcription factors in
controlling terminal neuron differentiation (rather than initial commitment to a neural fate).
Family studies, case -
control studies, and population cohorts are picking up this kind of signal everywhere.
Family - based
studies seemed to fall out of fashion a little bit with the rise of the case -
control study, but they're making a huge comeback now for a variety of reasons.
The ADSP Discovery Phase is comprised of a
Family - Based
study and a Case - Control S
study and a Case -
Control StudyStudy.
Integrating a
family - focused approach into child obesity prevention: rationale and design for the My Parenting SOS
study randomized
control trial.
Research Focus: My research focuses on
studying the role of different TNF super
family members in
controlling allergen induced asthma exacerbations and airway remodeling.
Qualified investigators can obtain: (1) cleaned, quality
control checked sequence data, (2) information on the composition of the
study cohorts (e.g. case -
control,
family based, and epidemiology cohorts), (3) descriptions of the
study cohorts included in the analysis, and (4) accompanying phenotypic information such as age at disease onset, gender, diagnostic status, and cognitive measures.
Ongoing T2D research activities at CRGGH include 1) whole - exome sequencing of African
families with at least four affected members (data generation is complete and analysis is ongoing), 2) GWAS of 1,200 cases and 1,200
controls from West Africa using the new and more efficient African - centric Affymetrix Axiom genome - wide array with more than 2 million markers, and 3) whole genome expression analysis on skeletal muscle obtained from biopsy from 45 subjects (expression QTL (eQTL)
studies on the dataset are complete).
MC1R genotype as a predictor of early - onset melanoma, compared with self - reported and physician - measured traditional risk factors: an Australian case -
control -
family study.
Cutaneous malignant melanoma in women is uncommonly associated with a
family history of melanoma in first - degree relatives: a case
control study.
Second, says Brody, his
study has found a host of other genes that «
control a whole
family of metabolites» in the folate and B12 pathway.
One is titled CHARGE (Childhood Autism Risk from Genetics and Environment), a population - based case -
control study that has enrolled over 1,800 index children and their
families.