Not exact matches
Research from UW Medicine and collaborators indicates that a drug - like molecule can activate
innate immunity and induce genes to
control infection in a range of RNA viruses, including West Nile, dengue, hepatitis C, influenza A, respiratory syncytial, Nipah, Lassa and Ebola.
With respect to biological applications, the group is focusing on how cellular heterogeneity and cell - to - cell communication drive ensemble - level decision - making in the immune system, with an emphasis on «two - body» interaction (e.g., host cell - virus interactions,
innate immune
control of adaptive
immunity, tumor infiltration by immune cells).
The Caenorhabditis elegans germ line regulates distinct signaling pathways to
control lifespan and
innate immunity.
This diverse «toolkit» of genes correlates with critical aspects of all metazoan body plans, and comprises cell cycle
control and growth, development, somatic - and germ - cell specification, cell adhesion,
innate immunity and allorecognition.
In order to prevent autoimmunity and «collateral damage» to host tissues in the course of responses to pathogens,
innate and adaptive
immunity are subject to stringent
control mechanisms.