Sentences with phrase «control of gene expression»

Researchers have identified a host of factors involved in epigenetic control of gene expression and development, but many of the precise mechanisms underlying this type of regulation remain unclear.

Stress, epigenetic control of gene expression and memory formation.

The Kind group uses these techniques to study the role of genome architecture and chromatin context in temporal and spatial control of gene expression in development and disease.

With these techniques at our disposal, we aim to elucidate the role of genome architecture and chromatin context in regulating the temporal and spatial control of gene expression in development and disease.

Adrian R. Krainer Posttranscriptional control of gene expression; pre-mRNA splicing mechanisms, fidelity and genetic diseases; alternative splicing; RNA - protein interactions; cancer

Altered control of gene expression at the level of protein synthesis has emerged as an important but ill - defined player in this process.

As with alternative splicing, activation of different combinations of landing sites makes possible exquisite control of gene expression, but researchers have yet to figure out exactly how all these regulatory elements really work or how they fit in with alternative splicing.

The modern study of gene regulation started in the 1950s, but researchers only started to unravel the complex array of histone modifications that fine - tune chromatin control of gene expression 20 years ago.

Following up on clues — including the fact that PMS is 56 percent heritable — the NIH researchers studied the genetic control of gene expression in cultured white blood cell lines from women with PMDD and controls.

You need very fine control of gene expression.

Possibilities range from the temperature - induced control of gene expression and tumour metabolism to the cell - selective treatment of disease and the study of heat dissipation in integrated circuits.

The team then compared the proteomics data to sample - matched transcriptomics data to characterize the global control of gene expression at the post-transcriptional level.

Colaboration with Prof. Dr. Michael Sattler, Prof. Dr. Ketting and Dr. Jean - Yves Roignant PROJECT INFORMATION: RNA - binding proteins (RBPs) are critical players in the posttranscriptional control of gene expression and regulate various mRNA processing steps, including splicing, 3» end processing and translation.

As a partner of the European Consortium 3D - REPERTOIRE and coordinator of the Spanish Structural Genomics Consortium GENES, our group studies several protein complexes and molecular machines, some of which are related to the epigenetic control of gene expression.

Julia received her Ph.D. in biological chemistry in 2010 studying temporal and spatial control of gene expression.

«It offers a brand new approach to the control of gene expression in microbial cultivation,» Prof. Stephanopoulos said.

The discovery and other findings about the missteps fueling tumor growth came from studying the epigenome, which is the array of proteins and chemicals on or attached to DNA that work in concert to orchestrate the control of gene expression in a tissue - specific manner.

The work has led him to explore the role of protein phosphorylation in a diverse array of cellular functions, including transformation, cell communication, cell adhesion, cell - cycle regulation, the control of gene expression, and protein degradation.

Beyond the DNA sequence, so - called epigenetic information contributes to the control of gene expression.

A new cellular signal discovered by a team of scientists at the University of Chicago and Tel Aviv University provides a promising new lever in the control of gene expression.