Sentences with phrase «control of single genes»

Not exact matches

They asked the question, What controls the activity of a single gene, turning it on or off?

Molecular geneticists dream of having a similarly comprehensive view of networks that control genes: For example, they would like to identify rules explaining how a single DNA sequence can express different proteins, or varying amounts of protein, in different circumstances (see p. 80).

This trait is caused by the accumulation of large amounts of β - carotene that was reported to be controlled by a single recessive gene ore.

The authors also provide experimental validation for using active genetics as an efficient means for targeted gene insertion, or «transgenesis,» and single - step replacement of genetic control elements.

After analyzing brain tissue samples, the researchers identified an area of the gene where a single change reduced BDNF levels in the hypothalamus, a key area that controls eating and body weight.

In a sign of the method's power, Pritchard's team also detected selection in traits controlled not by a single gene, but by tiny changes in hundreds of genes.

Allan - Herndon - Dudley syndrome is caused by defects to a single gene that controls the flow of thyroid hormone to the brain.

Adding some complexity to the seemingly simple life of a single - celled organism, researchers have found that a green alga uses snippets of RNA to control its genes.

Researchers have achieved new insights into how the global control of all genes on a single chromosome can be established and maintained throughout the lifetime of an organism.Their findings about...

«If we can pinpoint which genes control the development of each neuron type, we can generate them in the petri dish from a single sample of human skin cells,» said Dr. Huang.

(A) CummeRbund heat map of genes that were differentially expressed in control and single and double ABL1 and ABL2 knockdown cells.

RESCUE and REVERSE are two separate randomized, double - masked, sham - controlled pivotal Phase III trials designed to evaluate the efficacy of a single intravitreal injection of GS010 (rAAV2 / 2 - ND 4) in subjects affected by LHON due to the G11778A mutation in the mitochondrial ND4 gene.

To explore the possibility of common genetic pathways within the respective pathophysiologies, nine ADHD candidate single nucleotide polymorphisms (SNPs) in seven genes were tested for association with PD in 5333 cases and 12,019 healthy controls: one variant, respectively, in the genes coding for synaptosomal - associated protein 25 k (SNAP25), the dopamine (DA) transporter (SLC6A3; DAT1), DA receptor D4 (DRD4), serotonin receptor 1B (HTR1B), tryptophan hydroxylase 2 (TPH2), the norepinephrine transporter SLC6A2 and three SNPs in cadherin 13 (CDH13).

Homozygosity mapping of 5 cases (4 full - sibs, 1 half - sib) and 5 controls (2 parents, 3 full - sibs) via Illumina CanineHD SNP genotyping BeadChips identified a single chromosome (canine chromosome 36; CFA36) of interest where the gene containing a responsible mutation is expected to be located.

Conditions that are controlled by a single gene fall into one of four inheritance patterns.