Sentences with phrase «control synaptic vesicle»
Nguyen plans on applying IM - LARIAT technology to a living brain, where she would be able to control synaptic vesicle transmission and communication between neurons.
https://www.sciencedaily.com/ Not exact matches
The synaptic vesicle protein that mediates membrane fusion during exocytosis also regulates the rate and extent of this process by controlling vesicle tethering.
The next major advance which moved this analysis from a cell physiological to a molecular level was accomplished by Scheller and Südhof who made overlapping contributions that characterized the proteins that controlled the two key steps of transmitter release: 1) They showed the mechanism by which the vesicle is mobilized to the release sites of the presynaptic terminal, where the synaptic vesicle first fuses with the membrane of the sending neuron and then leaves the cell, and 2) they also discovered how Ca2 + drives the vesicle to release its contents.
«It is a sort of shepherding effect by alpha - synuclein that occurs away from the synapse itself, and controls the number of synaptic vesicles used in each transmission,» Fusco said.