Sentences with phrase «control trial design»

More than half of the studies (n = 7) had a cross sectional design, four were case — control comparing institutionalised with family raised children, only one used a randomised control trial design (BEIP) and only one had a longitudinal design (Bernier et al. 2004).

This paper focuses on the most recent evaluation of the D.C. Opportunity Scholarship Program, which is the only voucher program funded and authorized by federal law and uses a randomized control trial design.29

We take advantage of a unique randomized control trial design.

Others did recruit enough patients but didn't use a randomized controlled trial design, which weakened results.

This study was a randomized, double - blind, placebo - controlled trial designed to characterize the safety, tolerability and pharmacokinetics of AVI - 7288 after daily repeat dosing.

To definitively prove there is a problem, Bjursten says scientists would have to find a plausible biological mechanism to explain these differences — and then run two randomized controlled trials designed to look at whether the donor's sex and pregnancy history affect the recipient.

The Maternal Vitamin D Osteoporosis Study (MAVIDOS) is the first randomised, placebo - controlled trial designed to measure the impact of pregnancy vitamin D supplementation on the bone health of babies using bone density scanning.

Using a randomised controlled trial design, we aim to investigate the efficacy and cost - efficacy of a dietary program for the treatment of Major Depressive Episodes (MDE).

The research presented here is the first large - scale randomized - control trial designed to measure what students learn from school tours of an art museum.

It was «the first large - scale randomized - control trial designed to measure what students learn from school tours of an art museum.»

The purpose of this project is to perform the evaluation portion of a randomized control trial designed to assess the impact of The Match School Foundation, Inc.'s teacher training program for novice teachers on outcomes such as achievement growth of teachers» students, principal ratings, and retention with the ultimate goal of improving K - 12 education.

«The Educational Value of Field Trips,» by Jay P. Greene, Brian Kisida, and Daniel H. Bowen, which appeared in the Winter 2014 issue of Education Next, is the first large - scale randomized - control trial designed to measure what students learn from school tours of an art museum, this one in Bentonville, AR.

Because we used a randomized controlled trial design, we were able to establish convincingly that our intervention was not only the cause of the educational gains; importantly, the program was also inexpensive.4

A study by Jay P. Greene, Brian Kisida and Daniel H. Bowen, «The Educational Value of Field Trips,» was the first large - scale randomized - control trial designed to measure what students learn from school tours of an art museum.

Similarly, a randomized control trial designed to improve nurturant and involved parenting reduced adolescent risky behavior, but only amongst those with the short allele (Brody et al., 2009b).

To help achieve our vision we set about to evaluate the impact of our school based program using a randomized controlled trial design.

The study used a randomized, controlled trial design in which 220 families receiving the Early Start program were contrasted with a control series of 223 families not receiving the program.

The study used a randomized, controlled trial design in which 220 families who were participating in the Early Start program were contrasted with a control series of 223 families who were not participating in the program.

Both of the evaluations cited used a randomized controlled trial design, which is considered the «gold standard» evaluation methodology.

This study aimed to evaluate the efficacy of the Fun to Learn for the Young (FLY) program using randomized controlled trial design with no blinding of participants.

Not exact matches

The sample size was small, and the researchers stated that the research findings indicate the need for a randomised control trial (RCT) as RCT's are widely recognised as the best study design.

Design: In this parallel - group randomized controlled trial, we enrolled household shoppers across New Zealand who owned smartphones and were aged ≥ 18 y. Eligible participants were randomly assigned (1:1:1) to receive either traffic light labels (TLLs), Health Star Rating labels (HSRs), or a control [nutrition information panel (NIP)-RSB-.

Primarily because we do not find the same benefits in better - designed studies — sibling comparison studies and the PROBIT randomized controlled trial.

Legacy was developed by CDC in collaboration with the University of Miami, UCLA, and RTI International, and designed as a randomized controlled trial to test the idea that the Legacy intervention during early childhood might improve children's development.

Researchers at St. Michael's Hospital undertook a systematic review and meta - analysis of all of the available evidence from randomized controlled trials, the gold standard of research design.

Promising results from the new trial would be a major step forward for a field that has long been criticized for studies that are poorly designed, incomplete or lack control - group comparisons, as well as for the peddling of unproved therapies in many clinics worldwide.

The determination of each efficacy level was also based on the rigor and quantity of published studies on the drug class: to be in Level A, for example, a class of drugs must have been supported by at least two «Class I» studies — well - designed, double - blind, randomized, placebo - controlled clinical trials.

Rwanda will present safety and efficacy data on 50 patients at the American Urology Association in May 2011, and a randomized, controlled trial with 150 participants, designed to compare PrePex with the conventional surgical method is currently ongoing.

Thanks to the crossover intervention trial design, the researchers could control most of the potential confounders, such as population characteristics or past medical history.

Larger, well - designed studies, such as cluster randomized trials, are ultimately needed to confirm the effectiveness of this strategy,» writes Alice Y. Guh, M.D., M.P.H., and L. Clifford McDonald, M.D., of the Centers for Disease Control and Prevention, Atlanta.

BrainGate2 clinical trial participant T7 used the brain - computer interface to control a specially designed radial keyboard.

The design is used to mimic randomized controlled trials.

The point is that the traditional model of designing a few - month - long placebo controlled trial of a pain score outcome is not sufficient.

Well - designed, placebo - controlled trials of the drug in men who do not meet the standard criteria for treatment have been scant in number, and their results have been inconsistent.

However, the first Mayo trial, designed to be double - blind, randomised, placebo - controlled research and purporting to have duplicated the conditions in Cameron's clinical trial, disproved the Cameron - Pauling thesis.

This pivotal trial is the largest study conducted of renal artery denervation as a treatment for resistant hypertension and the most rigorously designed, including blinding and a sham treatment in the control arm.

Although reanalysis of the available evidence is important, the ability to properly control for bias and confounding [factors that can influence outcomes] in observational studies is often limited, and without randomized controlled trials specifically designed to test the hypothesis, the issue of nonspecific effects of vaccines may remain subject to continuing debate.»

«To really sort out if [stem] cells can treat these children, we need to do randomized, controlled trials that are well designed and well controlled, and that's what we intend to do,» says Kurtzberg, professor of pediatrics and pathology at Duke.

Using a randomized, placebo - controlled clinical trial (RCT) design, they randomized 48 participants into four equal groups of 12 people: low - to - moderate intensity, high - volume aerobic exercise (LO: HI); high - intensity, low - volume aerobic exercise (HI: LO); low - to - moderate intensity, low - volume aerobic exercise (LO: LO); and placebo (PLA) for an eight - week period.

Led by University of Texas Austin researcher Dr Steve Bellan, and in collaboration with the U.S. Centers for Disease Control and Prevention (CDC), the study on the design of CDC's vaccine trial in Sierra Leone is published in The Lancet Infectious Diseases.

Dr Gambhir said the team looked at whether a randomized control trial (RCT)-- where all people in the population have the same chance of being selected; or a stepped - wedge cluster trial design — which would give vaccine to healthcare workers and eventually treat all of them — is most safe and effective in evaluating a vaccine.

John DeLuca, PhD, VP of Research & Training chairs Workshop 6: Cognitive Rehabilitation in MS. Dr. DeLuca discusses assessment of cognitive problems and introduces common evidence - based techniques for improving cognitive functioning in persons with MS. Nancy Chiaravalloti, PhD, director of Neuropsychology & Neuroscience Research, presents two recent double - blind, placebo - controlled, randomized control trials of behavioral interventions designed to specifically improve learning and memory in persons with MS. Yael Goverover, PhD, OT, focuses on techniques to improve learning and memory, with a specific emphasis on improving everyday functional activity.

So, even if (as I suspect will be the case), better designed double - blind and controlled trials eventually show no specific benefits from this training, at least the participants will have had fun taking part.»

Integrating a family - focused approach into child obesity prevention: rationale and design for the My Parenting SOS study randomized control trial.

The design and rationale of a multicenter clinical trial comparing two strategies for control of systolic blood pressure: the Systolic Blood Pressure Intervention Trial (SPRtrial comparing two strategies for control of systolic blood pressure: the Systolic Blood Pressure Intervention Trial (SPRTrial (SPRINT).

In addition, randomized controlled trials proving sex - specific effects by adequately designed interventions are widely missing.

Our fully - curated design - controlled software and annotated bioinformatics pipeline provide the most comprehensive bioinformatics solutions to stratify and monitor patients and support patient treatment and clinical trials.

RESCUE and REVERSE are two separate randomized, double - masked, sham - controlled pivotal Phase III trials designed to evaluate the efficacy of a single intravitreal injection of GS010 (rAAV2 / 2 - ND 4) in subjects affected by LHON due to the G11778A mutation in the mitochondrial ND4 gene.

Tests developed under design control and manufactured under cGMP stratify patients in a far more reproducible way, being critical to optimize treatment and select patients for clinical trials.

We also performed subgroup meta - analyses by type of prevention (primary v secondary: in this study, trials involving healthy populations or patients with any specific disease except for cardiovascular disease were classified as primary prevention trials, and trials involving patients with cardiovascular disease were classified as secondary prevention trials), type of supplement by quality and dose (each supplement, vitamins only, antioxidants only, or antioxidants excluding vitamins), type of outcome (cardiovascular death, angina, fatal or non-fatal myocardial infarction, stroke, or transient ischaemic attack), type of outcome in each supplement, type of study design (randomised, double blind, placebo controlled trial v open label, randomised controlled trial), methodological quality (high v low), duration of treatment (< 5 years v ≥ 5 years), funding source (pharmaceutical industry v independent organisation), provider of supplements (pharmaceutical industry v not pharmaceutical industry), type of control (placebo v no placebo), number of participants (≥ 10000 v < 10000), and supplements given singly or in combination with other vitamin or antioxidant supplements by quality.