Testing each of the roughly 22,000 mammalian genes against miRNAs one by one, to see which ones are
controlled by the molecules, is inordinately painstaking and costly.
MN: Every part of our body is
controlled by molecules, so you have to explain on a molecular level.
However, once opiate addiction had developed, the scientists observed a functional switch to a separate molecular memory pathway,
controlled by a molecule called calmodulin - dependent kinase II or «CaMKII.»
Electron ejection from multiple N2 orbitals,
controlled by the molecule's orientation relative to a laser, produces attosecond light spectra that can reveal molecular dynamics.
Not exact matches
And in any such case, it then becomes the interactions which experience has shown will have an impact on the
molecule which
controls the shape it takes and not anything intrinsic to the
molecule considered in itself, or explained simply
by the quantum mechanics of its constituents.
The objects of his study range from a class of
molecules that have the basic self - duplicating property of living things, through cells which suggest purely physical systems, through animals which give increasing evidence of having minds, to human beings in whom streams of consciousness seem to involve continual choices of action, at the opposite pole from
control by impersonal laws of nature.
Scientists Elizabeth D. Prescott and David Julius of the University of California, San Francisco, announced they had identified a lipid
molecule called PIP2 that plays a crucial role in
controlling the strength of the burning sensation caused
by capsaicin.
«We now need to identify how this effect is pass through multiple generations
by investigating the effects alcohol has on the genome and epigenome (
molecules that
control gene translation),» said Cameron.
«This means that one can
control at will in which electrode the heat is released
by simply using the proper
molecule.»
Taken together, these findings show that puberty, fertility, attraction and sex are all
controlled by a single
molecule; kisspeptin.
But it's only because it's on the microscopic level that this structure can overcome the problem of maintenance: the
molecules that
control the wheel and axle reach it
by diffusing through the cell's cytoplasm.
Now research in rodents suggests that gut microbes may alter the inventory of microRNAs —
molecules that help keep cells in working order
by managing protein production — in brain regions involved in
controlling anxiety.
Varghese and her team showed that they could
control the differentiation of human pluripotent stem cells into functional osteoblasts — bone - building cells — simply
by adding the
molecule adenosine to their growth medium.
Furthermore, the researchers found that
by altering the size of the ripples, and the type of
molecules on the surface, they could achieve fast and
controlled motion of
molecules other than water..
Fashioning individual
molecules atom
by atom could allow researchers to study atomic collisions in the most
controlled environment possible, as well as to observe how
molecules behave in isolation.
The Princeton researchers posited that they could
control the light that bounces off a
molecule or any substance
by controlling the light shone on it, which would allow them to alter how it looks.
«
Molecules for
controlling bacterial behavior designed
by chemists.»
By tweaking the smallest units of life, scientists are making bigger gains in producing alternative and renewable energy, with recent efforts aimed at
molecule - level
controls and promoting fractal growth patterns to create different fuels and improve efficiencies.
MicroRNAs are short RNA
molecules that typically bind to complementary sequences in messenger RNAs, thereby
controlling the amounts of specific proteins produced
by cells.
«The synthetic
molecules made
by our lab don't exactly look like rhamnolipids, but they can
control bioactivities, such as swarming movements, surface adhesion and biofilm formation.»
Using an innovative crystallization technique for studying three - dimensional structures of gene transcription machinery, an international team of researchers, led
by scientists at Penn State, has revealed new insights into the long debated action of the «magic spot» — a
molecule that
controls gene expression in Eschericahia coli and many other bacteria when the bacteria are stressed.
First, it is a quality
control mechanism used
by cells to eliminate faulty messenger RNA (mRNA)--
molecules that are essential for transcribing genetic information into the construction of proteins critical for life.
Nitrogen helps plants produce proteins, including the key
molecules that
control photosynthesis, the process
by which the sun's energy is captured and converted into the carbon compounds that are the raw material for growth.
By controlling the alignment of these
molecules, scientists can literally tie them in a knot.
By varying the arrangement of
molecules in the supporting layers, the scientists were able to
control how often the introduced
molecules switched.
Advances in understanding the cells and
molecules that transmit pain signals are providing new targets for drugs that could relieve various kinds of pain — including those poorly
controlled by existing therapies
A normal cell has chemical receptors on its surface that link up with specific
molecules generated
by the body and
control the timing of such functions as eating and sleeping.
«In step toward
controlling chemistry, physicists create a new
molecule, atom
by atom: Study paves the way for creating on, off buttons for chemical reactions.»
The team then went a step further, putting the rock and soil samples in a
controlled combustion chamber that released carbon at different temperatures, allowing the carbon
molecules to be sorted
by their latent energy, an indicator of their chemical structure, and the amount of radiocarbon they contain.
«
By integrating a light - activated
molecule into the traditional picture of latent heat, we add a new kind of
control knob for properties such as melting, solidification, and supercooling,» says Grossman, who is the Morton and Claire Goulder and Family Professor in Environmental Systems as well as professor of materials science and engineering.
The researchers found that the expression of a clock gene named frequency (frq) is
controlled by a long non-coding RNA named qrf (frq backwards) − an RNA
molecule that is complementary, or antisense, to frq.
The researchers make changes in the model such as computationally adding a potential drug or virtually knocking out the gene for a
molecule produced
by the immune system to search for changes that cause the granuloma to move toward a
controlled state.
We were able to replicate this process in a biologically - reasonable way in the lab
by controlling the electrostatic charge of the
molecules that form our synthetic liquid organelles.
Molecules produced on demand
by the host's genes have lots of different jobs that might help or hurt the bugs: immune responses, digestive enzymes, physiological «climate
control» and metabolism, among others.
«Knowledge of the 3 - D structure of these channels is required to understand the molecular basis of channel opening and closing, and how this process is
controlled by a wide variety of endogenous
molecules and pharmacological modifiers,» said Rodney Kellems, Ph.D., professor and chair of the Department of Biochemistry and Molecular Biology at UTHealth Medical School.
A research team led
by Shunsuke Yoshizawa, ICYS researcher, NIMS, Takashi Uchihashi, leader of the Surface Quantum Phase Materials Group, MANA, NIMS, Emi Minamitani, assistant professor, School of Engineering, University of Tokyo, Toshihiko Yokoyama, professor, IMS, NINS, and Kazuyuki Sakamoto, professor, Graduate School of Advanced Integration Science, Chiba University, succeeded in precisely
controlling the transition temperature of atomic - scale - thick superconductors using magnetic organic
molecules.
«In addition, we can precisely
control how many
molecules bind to the graphene
by adjusting an applied voltage,» explains Dr. Jörg Rappich from the HZB Institute for Silicon Photovoltaics, Rösicke's advisor.
Multicomponent reactions are methods which are superior in economy and efficiency to methods of bonding
molecules by repeating reactions, but it was necessary to
control the number of
molecules to be bonded and locations of the bonds, so their applications were limited.
This can be accomplished in part
by precisely
controlling the orientation of dye
molecules and their distance from each other.
They form a pore with a filter that selectively allows the passage of potassium ions, and which is
controlled by the signaling
molecule cAMP.
Instead of slowly adding material
molecule by molecule, the coral animal actively constructs large chunks of minerals that it adds to its growing skeleton, helping it grow much faster than it otherwise could, and with greater
control.
These predictions, which were verified
by comparisons with high - resolution microscopic images of real
molecules on metal surfaces, may lead to
controlled, large - scale fabrication of tiny electrical wires and other nanomaterials for future devices.
They identified signals that white blood cells use to
control their behaviour, then one
by one disabled those signals — discovering that one particular
molecule called ERK5 could be manipulated to encourage white blood cells either to throw out pathogens better or to keep them inside and try to kill them for longer.
They now hope to create worms with artificial amino acids that can be
controlled by light or specific chemicals: a toolkit that would allow researchers to switch specific cells or
molecules on and off.
By applying varying amounts of ethanol and APS to paper that is coated with copolymers, the researchers were able to
control the swelling and shrinking of the
molecules and generate the colors and patterns needed to create a picture.
In other words, they varied the strength of chemical
control by changing the
molecule under study.
Scientists at the Centers for Disease
Control and Prevention (CDC) also contributed
by performing initial screening of the Gilead Sciences compound library to find
molecules with promising antiviral activity.
Using a powerful microscope that lets researchers see the formation of crystals in real time, a team led
by the Pacific Northwest National Laboratory found that negatively charged
molecules — such as carbohydrates found in the shells of mollusks —
control where, when, and how calcium carbonate forms.
In 1998 Aizenberg joined Bell Labs as a member of the Technical Staff where she has made several pioneering contributions including developing new biomimetic approaches for the synthesis of ordered mineral films with highly
controlled shapes and orientations, and discovering unique optical systems formed
by organisms (microlenses and optical fibers) that outshine technological analogs, and characterized the associated organic
molecules.
Regulating cell surface glycosylation
by small
molecule control of enzyme localization.