A new social communication intervention for children with autism: Pilot randomized
controlled treatment study suggesting effectiveness.
Not exact matches
Besides randomized
controlled clinical trials, there are a number of ways researchers can
study how a particular cancer
treatment is playing out in the real world: there are retrospective
studies, observational
studies, and even prospective research done using patient registries.
Living Goods told us at that time that the results from the RCT were not going to be reliable due to spillover of the intervention into
control locations and incorrect matching of the
treatment area and the
treatment survey area — issues that reduce the statistical power of the
study.1
The
study discovered that stage 3 and 4 breast cancer women who supplemented their diet with virgin coconut oil during breast cancer
treatment improved fatigue, dyspnea, sleep difficulties, and loss of appetite compared to the
control group.
For the same reason, it is not easy to prove
treatment efficacy by means of
controlled, randomized
studies, the «gold standard» for evaluating new therapies.
In the only
controlled, randomized scientific
study to compare graduated extinction and «positive routines» head - to - head, there were no significant differences in
treatment outcomes for kids (Adams and Rickert 1989).
Studying breastfeeding behaviours or outcomes is difficult since it is not possible to randomly assign mothers and infants to
treatment groups or to
control the duration of the process.
less than or equal to lamivudine Acquired Immune Deficiency Syndrome Antiretroviral therapy, usually means 1 - 2 drugs, used in early
studies Antiretroviral zidovudine (also known as ZDV) Breastfeeding Baby Friendly Hospital Initiative Breastfeeding and HIV International Transmission
Study Combined antiretroviral therapy Centers for Disease
Control and Prevention Deoxyribonucleic Acid Exclusive Breastfeeding Enzyme Linked Immunosorbent Assay Food and Agrigulture Organization Fixed dose combination ART, e.g., lamividine, stavudine, and nevirapine Highly Active Antiretroviral Therapy, 3 or more drugs for more effective
treatment used in later
studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug as AZT)
The objective of the current
study was to systematically review randomised
controlled trials of parenting programmes for the
treatment of children with conduct problems.
No
controlled studies have shown any particular
treatment to be effective.
One way out of this dilemma, Daviglus notes, is to design a
study in which patients suffering from hypertension get
treatment, and doctors analyze the results based on how well the patients» blood pressure was
controlled.
According to the
study, in the
treatment of small renal tumors, the ideal outcome of both complete oncologic
control and preservation of renal function is not presently available.
Previous
studies have suggested that various forms of meditation can improve attention and reduce stress, but there have been few randomised
controlled trials — the best way of testing a
treatment's effectiveness.
«Meta
studies have shown that the
controlled grafting of fecal transplantation from healthy donors is a safe and very effective
treatment of acute diarrheal diseases caused by the pathogenic bacterium Clostridium difficile,» said Sieglinde Angelberger, gastroenterologist at the University Clinic for Internal Medicine III of the Medical University of Vienna and author of the
study: «this was the reason why we applied this therapy for the
treatment of patients with chronic intestinal diseases.»
However, prior to this
study there has been a lack of randomized
controlled trials with a long - term follow - up that compare the effectiveness of noninvasive
treatments.
Scope of the problem A National Institute of Mental Health (NIMH)
study released this spring shows that 14 percent of patients with drug - resistant major depressive disorder experience a remission of symptoms after rTMS
treatment compared with a
control group, which reported a 5 percent rate of remission.
The bookended pre - and post-transplant
treatments, which have been tested separately in other
studies, already had promising track records in
controlling cancer and preventing severe GVHD.
The
study, «Prevalence of hypertension, awareness,
treatment and
control in the Hispanic Community,» led by Dr. Paul D. Sorlie of the National Heart, Lung, and Blood Institute (NHLBI), sampled 16,400 individuals, making it one of the largest and most rigorous health
studies of the Hispanic community.
Another problem is that modeling
studies, like this one, are inherently less powerful than other kinds of medical research: randomized clinical trials, the gold standard in medical research, in which patients are randomly assigned different
treatments or no
treatment; case -
control studies, which compare patients who have a condition with those who do not; or cohort
studies, which determine the risk of contracting a disease by
studying a group of people with similar demographics.
In the
study, aid workers identified 11,000 of the poorest households in six impoverished regions of Ethiopia, Ghana, India, Pakistan, Peru, and Honduras, then divided them into
treatment and
control groups.
«These findings present a conundrum for designing Dravet syndrome
treatments that both
control seizures and improve social behavior,» noted Nephi Stella, another researcher on the
study from the UW departments of pharmacology and psychiatry and behavioral sciences.
(1) In this
study — the LIFEstyle
study performed in the Netherlands — 290 women were assigned to a 6 - month lifestyle - intervention programme preceding 18 months of infertility
treatment (intervention group) while 287 women were assigned to prompt infertility
treatment over the same 24 month
study period (
control group).
The
study examined 328 patients with cervical cancer and 1,312
controls, matched on age and decade, who enrolled in a hospital - based case -
control study drawn from 26,831 patients who received
treatment at Roswell Park Cancer Institute and completed the Patient Epidemiology Data System questionnaire between 1982 and 1998.
Nearly half (48 %) of patients with severe or difficult - to - treat asthma in The Epidemiology and Natural History of Asthma: Outcomes and
Treatment Regimens follow - up study (TENOR II) still had very poorly controlled (VPC) symptoms after more than a decade of treatment, according to a new study presented at the ATS 2016 International Co
Treatment Regimens follow - up
study (TENOR II) still had very poorly
controlled (VPC) symptoms after more than a decade of
treatment, according to a new study presented at the ATS 2016 International Co
treatment, according to a new
study presented at the ATS 2016 International Conference.
«Non-blind
studies more confidently concluded that differences between
treatment and
control groups were real, and not just due to chance variation.»
There was no significant increase in adverse events with any of the
treatments over the
control group, nor was there any difference in malaria incidence between groups during the one year period after the
study treatment was stopped, suggesting that monthly administration of DP is a safe and effective
treatment for reducing malaria among infants in regions with year - round transmission and high resistance to antifolates.
Yamaki and his co-authors recruited 255
study participants from alcoholism
treatment services at Kurihama National Hospital in Yokosuka, Japan: 134 alcoholic patients and 121 age - matched
controls or non-alcoholics, ranging in age from 41 to 85 years old.
The
study included 250 rheumatoid arthritis and spondyloarthritis patients undergoing Remicade
treatment who had never been previously treated with the biosimilar, and 77
control patients.
Study participants were randomly assigned to one of three
treatment groups for six months: (1) oral estradiol and progesterone at a dose similar to that in many birth
control pills (16 participants); (2) transdermal estradiol, better known as the estrogen patch, at a physiological replacement dose with cyclic progesterone (13 athletes); or (3) no estrogen (19 subjects).
The
study, «Intravenous augmentation
treatment and lung density in severe α1 antitrypsin deficiency (RAPID): a randomised, double - blind, placebo -
controlled trail,» published online will change how clinicians understand this
treatment and encourage them to consider its early use before the condition causes severe emphysema.
A certain cytokine, or small protein that helps cells communicate during immune responses, can
control whether immune cells promote or suppress inflammatory bowel disease, a finding that could lead to new
treatments, according to a
study led by Georgia State University.
It was such a significant improvement that the funding agencies for the
study paid for the 150 lots in the
control group to receive the cleaning - and - greening
treatment.
The
study, supported by grants from the National Institutes of Health and the U.S. Centers for Disease
Control and Prevention, assigned each cluster to one of three experimental options: a control group (meaning no treatment); a basic cleanup; or a «cleaning and greening» treatment, including a lawn, a few trees and a low perimeter fence — «to show that the lot was cared for and to deter illegal dumping.
Control and Prevention, assigned each cluster to one of three experimental options: a
control group (meaning no treatment); a basic cleanup; or a «cleaning and greening» treatment, including a lawn, a few trees and a low perimeter fence — «to show that the lot was cared for and to deter illegal dumping.
control group (meaning no
treatment); a basic cleanup; or a «cleaning and greening»
treatment, including a lawn, a few trees and a low perimeter fence — «to show that the lot was cared for and to deter illegal dumping.»
... Finally, this
study draws attention to the need for large
controlled clinical trials to determine if a combination of fall prevention strategies and
treatment with bone - active drugs might produce additive benefits on fractures, especially in high - risk populations such as those living in nursing homes.
«We used a highly
controlled experimental design, to ensure that any benefits of mindfulness training were not likely explained by people believing it was a better
treatment,» said co-author Dr Tom Freeman (Senior fellow of the Society for the
Study of Addiction), who was part of the research team while based at UCL.
The
study analysed which form of
treatment better alleviates non-specific lower back disability: a personally tailored exercise program targeting movement
control impairment, or a generic exercise program.
«The
study demonstrates that
controlled heating of one tumor can stimulate an immune response that attacks another tumor that has not had the heat
treatment,» said Steve Fiering, PhD, Norris Cotton Cancer Center researcher and professor of Microbiology and Immunology, and of Genetics at the Geisel School of Medicine at Dartmouth.
Those who turned down the
treatment were regarded as
controls for the purposes of the
study.
The
study participants also continued to improve eight - months after the
treatment ended, regaining a sense of hope and
control over their lives and reporting feeling more connected to and supported by others.
In their
study, which appears in the Journal of Educational Psychology, the researchers examined 117 infants, aged nine to 18 months, who were randomly assigned to
treatment and
control groups.
Contrary to the proclamations of many scientists, unreliable medical
study results do not disappear with large, randomized
controlled trials, in which subjects are randomly assigned to a
treatment or placebo group.
Limited awareness and ineffective
treatment meant that only eight per cent of people with hypertension had their condition under
control, compared to a rate of 14 per cent in India, the highest of the six countries
studied.
«Despite having good
treatments available, current reports suggest that fewer than half of individuals who need therapy are actually getting appropriate HIV medicine to
control their virus, leading to more transmission of disease,» says lead
study author Maunank Shah, M.D., Ph.D., an assistant professor of medicine at the Johns Hopkins University School of Medicine.
We would like to consider doing it on a larger scale, maybe having several universities
studying patients with different diagnostic categories to see how a
controlled psychotherapy trial produces physical brain changes as a result of
treatment.
A systematic review of published
studies on the use of medical cannabis in children and adolescents finds a notable lack of
studies and a minimal number of the randomized,
controlled trials needed to confirm the effectiveness of a
treatment.
The original, randomized, open label
study, which enrolled 20 outpatient men with cirrhosis and recurrent HE receiving standard - of - care (SOC)
treatment, had previously reported that a single FMT enema after antibiotic pretreatment improved cognitive function at Day 20 and reduced HE episodes and hospitalizations over the following 5 months compared with SOC.1 The long - term outcomes of this
study, which were presented today at The International Liver Congress ™ 2018 in Paris, France, demonstrated sustained and statistically significant reductions in the number of HE episodes and hospitalizations as well as improvements in cognitive function over 1 year in the men who received FMT compared with the
control group.
«While hypertension awareness,
treatment and
control have improved overall since the early 2000s, all three remain worse in young adults — those aged 18 - 39,» said senior
study author Andrew Moran, M.D., M.P.H., an assistant professor at Columbia University Medical Center in New York.
In animal models, the modified T cells greatly reduced the tumor burden and prolonged overall survival: All mice that received the modified T cells were alive 44 days after
treatment versus 29 percent and 17 percent of the
study's two
control groups.
Clinical
studies thus far have failed to identify an effective
treatment strategy when a combination of targets
controlling aspects of neuroprotection, neuroinflammation, and neuroregeneration is needed.
This pivotal trial is the largest
study conducted of renal artery denervation as a
treatment for resistant hypertension and the most rigorously designed, including blinding and a sham
treatment in the
control arm.