Sentences with phrase «controlled trial number»

Type of Study: Randomized controlled trial Number of Participants: Adults: 16 to 42 years, Children: 1 to 23 months
Type of Study: Randomized controlled trial Number of Participants: 63 Intervention, 49 Methadone - only
Type of Study: Randomized controlled trial Number of Participants: 110 families (mother, stepfather, and child [ren]-RRB-
Type of Study: Randomized controlled trial Number of Participants: 38 children and their families
Type of Study: Randomized controlled trial Number of Participants: 634 families provided pre and posttest data.
Type of Study: Randomized controlled trial Number of Participants: Control group: 275, Intervention group: 607
Type of Study: Randomized controlled trial Number of Participants: 114 (demographic breakdown below reflects initial 120 participants)
Type of Study: Randomized controlled trial Number of Participants: 1139 allocated to treatment; 627 seen in this follow - up
Type of Study: Randomized controlled trial Number of Participants: 37 adolescents and their families
Type of Study: Randomized controlled trial Number of Participants: 120 children and 113 parents (7 parents had 2 children enrolled in the study)
Type of Study: Randomized controlled trial Number of Participants: 93, plus 48 children not in foster care

Not exact matches

Besides randomized controlled clinical trials, there are a number of ways researchers can study how a particular cancer treatment is playing out in the real world: there are retrospective studies, observational studies, and even prospective research done using patient registries.
First, the topline numbers: The study was an observational one rather than a randomized control trial, the latter of which is considered to be the «gold standard» of clinical studies.
Of note, our point estimate for premature death exceeds the annual number of U.S. deaths from cervical cancer (3,909), asthma (3,361), or influenza (3,055).45 If a randomized control trial were to demonstrate similar effects to those reported in the observational literature, the «number needed to treat» with optimal breastfeeding to prevent a case of maternal hypertension would be 35, to prevent a maternal MI would be 135, and to prevent a case of breast cancer would be 385.
A review article of 3 randomized control trials, consisting of 212 women, found that acupuncture reduced the number of women who needed to a medical induction (33 % versus 54 %), but failed to find a difference in when the women went into labor.
Research shows that families typically receive roughly half of the number of home visits expected.16, 17 For example, across three randomized controlled trials conducted of Nurse Family Partnership, average dosage of visits ranged from 45 to 62 percent.18 Research also shows that many, perhaps most, families enrolled in home visiting programs drop out before their eligibility ends.16, 19,20 Some home visiting studies have varied the dosage that families were offered and found that fewer home visits produced outcomes similar to higher levels of exposure.21
Only one trial reported the following outcomes: mean number of antenatal visits, perceptions of control, breastfeeding on discharge and postpartum depression and so results were not included in a meta - analysis.
A randomised control trial conducted in BC [30] found home visits in early labour to be more effective than telephone triage in reducing the number of women attending the hospital for assessment before they are in labour and those attending before 3 cm cervical dilation, although the home visits had no impact on CS rates or birth outcomes.
In addition, there was no effect on breastfeeding duration when the pacifier was introduced at 1 month of age.280 A more recent systematic review found that the highest level of evidence (ie, from clinical trials) does not support an adverse relationship between pacifier use and breastfeeding duration or exclusivity.281 The association between shortened duration of breastfeeding and pacifier use in observational studies likely reflects a number of complex factors such as breastfeeding difficulties or intent to wean.281 A large multicenter, randomized controlled trial of 1021 mothers who were highly motivated to breastfeed were assigned to 2 groups: mothers advised to offer a pacifier after 15 days and mothers advised not to offer a pacifier.
Yale enrolled the largest number of participants at any one site (84 of 790) for these double - blind, placebo - controlled trials that investigated the efficacy of testosterone gel for multiple outcomes, including sexual function, physical function, and vitality.
The U.S. National Institute of Mental Health's Project Accept — a trial conducted by the HIV Prevention Trials Network to test a combination of social, behavioral and structural HIV - prevention interventions — demonstrated that a series of community efforts boosted the number of people tested for HIV and resulted in a 14 percent reduction in new HIV infections, compared with control communities.
Well - designed, placebo - controlled trials of the drug in men who do not meet the standard criteria for treatment have been scant in number, and their results have been inconsistent.
A systematic review of published studies on the use of medical cannabis in children and adolescents finds a notable lack of studies and a minimal number of the randomized, controlled trials needed to confirm the effectiveness of a treatment.
The study was the first randomized - controlled trial to examine the potential benefits of the low fat diet on the management of MS.. The study found no significant differences between the two groups in brain lesions detected on MRI brain scans or on other measures of MS.. But while the number of trial participants was relatively small, study leaders believe the significantly improved fatigue symptoms merited further and larger studies of the diet.
Randomized controlled trials showed that zinc supplementation can reduce the severity of morbidity from a number of common childhood infections, including diarrhea, pneumonia, and possibly malaria, by one - third.
We also performed subgroup meta - analyses by type of prevention (primary v secondary: in this study, trials involving healthy populations or patients with any specific disease except for cardiovascular disease were classified as primary prevention trials, and trials involving patients with cardiovascular disease were classified as secondary prevention trials), type of supplement by quality and dose (each supplement, vitamins only, antioxidants only, or antioxidants excluding vitamins), type of outcome (cardiovascular death, angina, fatal or non-fatal myocardial infarction, stroke, or transient ischaemic attack), type of outcome in each supplement, type of study design (randomised, double blind, placebo controlled trial v open label, randomised controlled trial), methodological quality (high v low), duration of treatment (< 5 years v ≥ 5 years), funding source (pharmaceutical industry v independent organisation), provider of supplements (pharmaceutical industry v not pharmaceutical industry), type of control (placebo v no placebo), number of participants (≥ 10000 v < 10000), and supplements given singly or in combination with other vitamin or antioxidant supplements by quality.
A 2014 double - blind placebo controlled trial assessed the effectiveness and safety of magnesium - sulfate - rich mineral water in 244 adult women with functional constipation; researchers observed a trend in improved number of normal stools for the group receiving magnesium - sulfate mineral water.
While there have been a number of human clinical studies, we need larger, randomized, properly - controlled clinical trials that look specifically at these suspects.
A systematic review of controlled yoga trials for adults with Type 2 diabetes (DM2) published in the Journal of Diabetes Research suggests that regular yoga practice may help to reduce a number of key risk factors and outcomes of the disease.
A large number of peer - reviewed research, including long - term randomized controlled trial data, has demonstrated that growth hormone replacement improves energy, strength, cardiac function, blood pressure, cholesterol levels, insulin sensitivity cognitive function, immunity, and psychologic well - being; decreases body fat; increases lean muscle; prevents and reverses heart disease; prevents and improves osteoporosis; and improves quality of life.
, Effect of a Moderate Fat Diet With and Without Avocados on Lipoprotein Particle Number, Size and Subclasses in Overweight and Obese Adults: A Randomized, Controlled Trial.
A number of small, controlled trials and case studies have tested the impact of yoga for those with spinal cord disease (myelopathy), traumatic brain injury, Guillain - Barre syndrome, amyotrophic lateral sclerosis (ALS), peripheral and diabetic neuropathies, adrenomyeloneuropathy, neurocardiogenic syncope, and other neurological anomalies.
Controlled trials and case studies suggest that consistent yoga practice is associated with improvements across a number of domains including tremor reduction, improved muscle strength, balance, posture, flexibility, and functional mobility, better cardiac health, and fewer symptoms of depression and anxiety.
Apart from the obvious difficulties with doing randomized controlled trials there is a number of confounding factors (59,60).
A classic Trackmania with a good control scheme and an impressive number of trials.
She leads a number of studies that evaluate education programs using rigorous econometric methods, including randomized control trials, propensity score matching methods, and other quasi-experimental evaluation designs.
This report finds the SAM approach could be replicated in a large enough number of schools, with enough fidelity to a theoretical model, that a randomized controlled trial would be a meaningful test of its impact.
The principals participate in the initiative in a number of ways, including serving as Distinguished Principals; completing NISL's Executive Development Program (EDP); receiving coaching from Distinguished Principals; or serving as control principals in a randomized controlled trial conducted by RAND Corporation.
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* 9 - Speed 948TE 4WD Automatic Transmission * (originally: $ 1095.00) Active Drive II badge; Auxiliary transmission oil cooler; Electronic range select; Hill descent control; Jeep Active Drive II; Off road suspension - Suspension Class: heavy duty - Descent Control - Auxilliary Transmission Cooler: auxiliary transmission fluid cooler - Consumer Generic Feature 0: AWD / 4WD - 4wd Type: on demand - Locking Hubs: automatic - Transfer Case: electronic hi - lo gear selection - Driven Wheels: four wheel drive * 3.2 L V6 24V VVT Engine W / ESS * (originally: $ 1745.00) 3.25 final drive ratio; 700 amp maintenance free battery; Dual bright exhaust tips; Engine oil cooler; Stop - start multiple VSM system - Engine Auto Stop / start - Engine Oil Cooler - Consumer Generic Feature 0: Upgraded Engine - Final Drive Ratio: 3.25 * Cold Weather Group * (originally: $ 895.00) All - season floor mats; Engine block heater; Exterior mirrors with heating element; Heated front seats; Heated steering wheel; Power heated mirrors; Remote start system; Windshield wiper de-icer - Heated Windshield Wiper Rests - Heated Passenger Seat: multi-level heating - Remote Engine Start - Block Heater - Consumer Generic Feature 0: Remote Start - Consumer Generic Feature 1: Heated seats - Exterior Mirror Adjustment: power - Heated Exterior Mirrors: heated - Heated Steering Wheel - Heated Driver Seat: multi-level heating - Floor Mats - Floor Mat Material: vinyl / rubber * 75th Anniversary Quick Order Package 26F * (originally: $ 0.00) Vehicle with standard equipment; 18 x 7.0 bronze painted aluminum wheels with 225 / 60R18 black side wall touring tires; 75th Anniversary badge; 75th Edition cloth / mesh bucket seats; 8.4 touchscreen display; Bronze fascia applique; Bronze grille surrounds; Bronze roof rails; Day light opening moldings; Power front and fixed rear full sunroof; Jeep 75th Anniversary Package; Jeep bronze badging; Navigation capable; 4 - way power driver lumbar adjust; 8 - way power driver seat; Remote USB port; SiriusXM satellite radio; Tangerine interior accents; Uconnect 8.4; Uconnect Access with 6 months trial - 1st Row Seat Type: bucket - 1st Row Upholstery: cloth - Consumer Generic Feature 0: Mobile Internet - Consumer Generic Feature 1: USB Inputs - Consumer Generic Feature 2: Sunroof / Moonroof - Consumer Generic Feature 3: Power Driver Seat - Consumer Generic Feature 4: Aux Audio Inputs - Roof Rack - One Touch Power Sunroof: one - touch power sunroof - 2nd Row Sunroof: fixed glass - Sunroof: power glass - Satellite Communications: Uconnect Access - Months Of Free Satellite Communications Service: 6 - Mobile Router - Height Adjustable Driver Seat: height adjustable - Driver Seat Adjustable Lumbar: power adjustable lumbar support - Number Of Driver Seat Power Adjustments: 8 * Comfort & Sound Group * (originally: $ 425.00) 9 amplified speakers with subwoofer; 4 - way power driver lumbar adjust; 8 - way power driver seat - Consumer Generic Feature 0: Power Driver Seat - Height Adjustable Driver Seat: height adjustable - Driver Seat Adjustable Lumbar: power adjustable lumbar support - Number Of Driver Seat Power Adjustments: 8This vehicle came with a free satellite radio subscription when it wcontrol; Jeep Active Drive II; Off road suspension - Suspension Class: heavy duty - Descent Control - Auxilliary Transmission Cooler: auxiliary transmission fluid cooler - Consumer Generic Feature 0: AWD / 4WD - 4wd Type: on demand - Locking Hubs: automatic - Transfer Case: electronic hi - lo gear selection - Driven Wheels: four wheel drive * 3.2 L V6 24V VVT Engine W / ESS * (originally: $ 1745.00) 3.25 final drive ratio; 700 amp maintenance free battery; Dual bright exhaust tips; Engine oil cooler; Stop - start multiple VSM system - Engine Auto Stop / start - Engine Oil Cooler - Consumer Generic Feature 0: Upgraded Engine - Final Drive Ratio: 3.25 * Cold Weather Group * (originally: $ 895.00) All - season floor mats; Engine block heater; Exterior mirrors with heating element; Heated front seats; Heated steering wheel; Power heated mirrors; Remote start system; Windshield wiper de-icer - Heated Windshield Wiper Rests - Heated Passenger Seat: multi-level heating - Remote Engine Start - Block Heater - Consumer Generic Feature 0: Remote Start - Consumer Generic Feature 1: Heated seats - Exterior Mirror Adjustment: power - Heated Exterior Mirrors: heated - Heated Steering Wheel - Heated Driver Seat: multi-level heating - Floor Mats - Floor Mat Material: vinyl / rubber * 75th Anniversary Quick Order Package 26F * (originally: $ 0.00) Vehicle with standard equipment; 18 x 7.0 bronze painted aluminum wheels with 225 / 60R18 black side wall touring tires; 75th Anniversary badge; 75th Edition cloth / mesh bucket seats; 8.4 touchscreen display; Bronze fascia applique; Bronze grille surrounds; Bronze roof rails; Day light opening moldings; Power front and fixed rear full sunroof; Jeep 75th Anniversary Package; Jeep bronze badging; Navigation capable; 4 - way power driver lumbar adjust; 8 - way power driver seat; Remote USB port; SiriusXM satellite radio; Tangerine interior accents; Uconnect 8.4; Uconnect Access with 6 months trial - 1st Row Seat Type: bucket - 1st Row Upholstery: cloth - Consumer Generic Feature 0: Mobile Internet - Consumer Generic Feature 1: USB Inputs - Consumer Generic Feature 2: Sunroof / Moonroof - Consumer Generic Feature 3: Power Driver Seat - Consumer Generic Feature 4: Aux Audio Inputs - Roof Rack - One Touch Power Sunroof: one - touch power sunroof - 2nd Row Sunroof: fixed glass - Sunroof: power glass - Satellite Communications: Uconnect Access - Months Of Free Satellite Communications Service: 6 - Mobile Router - Height Adjustable Driver Seat: height adjustable - Driver Seat Adjustable Lumbar: power adjustable lumbar support - Number Of Driver Seat Power Adjustments: 8 * Comfort & Sound Group * (originally: $ 425.00) 9 amplified speakers with subwoofer; 4 - way power driver lumbar adjust; 8 - way power driver seat - Consumer Generic Feature 0: Power Driver Seat - Height Adjustable Driver Seat: height adjustable - Driver Seat Adjustable Lumbar: power adjustable lumbar support - Number Of Driver Seat Power Adjustments: 8This vehicle came with a free satellite radio subscription when it wControl - Auxilliary Transmission Cooler: auxiliary transmission fluid cooler - Consumer Generic Feature 0: AWD / 4WD - 4wd Type: on demand - Locking Hubs: automatic - Transfer Case: electronic hi - lo gear selection - Driven Wheels: four wheel drive * 3.2 L V6 24V VVT Engine W / ESS * (originally: $ 1745.00) 3.25 final drive ratio; 700 amp maintenance free battery; Dual bright exhaust tips; Engine oil cooler; Stop - start multiple VSM system - Engine Auto Stop / start - Engine Oil Cooler - Consumer Generic Feature 0: Upgraded Engine - Final Drive Ratio: 3.25 * Cold Weather Group * (originally: $ 895.00) All - season floor mats; Engine block heater; Exterior mirrors with heating element; Heated front seats; Heated steering wheel; Power heated mirrors; Remote start system; Windshield wiper de-icer - Heated Windshield Wiper Rests - Heated Passenger Seat: multi-level heating - Remote Engine Start - Block Heater - Consumer Generic Feature 0: Remote Start - Consumer Generic Feature 1: Heated seats - Exterior Mirror Adjustment: power - Heated Exterior Mirrors: heated - Heated Steering Wheel - Heated Driver Seat: multi-level heating - Floor Mats - Floor Mat Material: vinyl / rubber * 75th Anniversary Quick Order Package 26F * (originally: $ 0.00) Vehicle with standard equipment; 18 x 7.0 bronze painted aluminum wheels with 225 / 60R18 black side wall touring tires; 75th Anniversary badge; 75th Edition cloth / mesh bucket seats; 8.4 touchscreen display; Bronze fascia applique; Bronze grille surrounds; Bronze roof rails; Day light opening moldings; Power front and fixed rear full sunroof; Jeep 75th Anniversary Package; Jeep bronze badging; Navigation capable; 4 - way power driver lumbar adjust; 8 - way power driver seat; Remote USB port; SiriusXM satellite radio; Tangerine interior accents; Uconnect 8.4; Uconnect Access with 6 months trial - 1st Row Seat Type: bucket - 1st Row Upholstery: cloth - Consumer Generic Feature 0: Mobile Internet - Consumer Generic Feature 1: USB Inputs - Consumer Generic Feature 2: Sunroof / Moonroof - Consumer Generic Feature 3: Power Driver Seat - Consumer Generic Feature 4: Aux Audio Inputs - Roof Rack - One Touch Power Sunroof: one - touch power sunroof - 2nd Row Sunroof: fixed glass - Sunroof: power glass - Satellite Communications: Uconnect Access - Months Of Free Satellite Communications Service: 6 - Mobile Router - Height Adjustable Driver Seat: height adjustable - Driver Seat Adjustable Lumbar: power adjustable lumbar support - Number Of Driver Seat Power Adjustments: 8 * Comfort & Sound Group * (originally: $ 425.00) 9 amplified speakers with subwoofer; 4 - way power driver lumbar adjust; 8 - way power driver seat - Consumer Generic Feature 0: Power Driver Seat - Height Adjustable Driver Seat: height adjustable - Driver Seat Adjustable Lumbar: power adjustable lumbar support - Number Of Driver Seat Power Adjustments: 8This vehicle came with a free satellite radio subscription when it was new.
F BD Blind Spot Monitor w / Rear Cross Traffic Alert F EM Matte Linear Dark Mocha Interior Trim F FV 20 Gray Metallic Alloy Wheels w / Machined Finish F GL Lexus Safety System + F HF Touch Free Power Rear Door F HS Heated and Ventilated Front Seats F NW Navigation System with 12.3 multimedia display, Lexus Enform Destinations (1 - year trial subscription included), Lexus Enform App Suite (Complimentary) F PA Intuitive Parking Assist F PM Premium Package Includes: Leather Trim Seats, Power - folding Outside Mirrors, Driver's Seat / Steering Wheel / Mirror Memory, Rain - sensing Wipers, Aluminum Roof Rails F SR Moonroof F TO Towing Prep Pkg: Transmission Cooler, Heavy Duty Alternator / Radiator (does not include ball mount) F WV Heated Matte Linear Dark Mocha Wood Steering Wheel P 3P Paint Protection Film Options: Abs Brakes (4 - Wheel) Air Conditioning - Air Filtration Air Conditioning - Front - Automatic Climate Control Air Conditioning - Front - Dual Zones Airbags - Front - Dual Airbags - Front - Knee Airbags - Front - Side Airbags - Front - Side Curtain Airbags - Passenger - Occupant Sensing Deactivation Airbags - Rear - Side Airbags - Rear - Side Curtain Airbags - Side - Curtain Rollover Sensor Engine Push - Button Start Traction Control Audio Auxiliary Input: Ipod / Iphone Integration Audio Auxiliary Input: Jack Audio Auxiliary Input: Usb Child Safety Locks Child Seat Anchors Latch System Crumple Zones Front Crumple Zones Rear Daytime Running Lights Led Doors Rear Door Type: Power Liftgate Interior Chrome Accents Passenger Seat Power Adjustments: 10 Passenger Seat Power Adjustments: Recline Safety Brake Pedal System Security Engine Immobilizer Security Remote Anti-Theft Alarm System Steering Wheel Power Tilt And Telescopic Universal Garage Door Opener Homelink 2 - Stage Unlocking Cruise Control Driver Seat Power Adjustments: 10 Drivetrain Drive Mode Selector Electronic Brakeforce Distribution Exterior Mirrors Heated Exterior Mirrors Integrated Turn Signals Exterior Mirrors Power Front Seatbelts: 3 - Point Fuel Economy Display Mpg Headlights Auto Delay Off Headlights Auto On / Off Headlights Dusk Sensing Impact Sensor Door Unlock Inside Rearview Mirror Auto - Dimming Multi-Function Display One - Touch Windows: 4 Rear Spoiler Roofline Spoiler Seatbelts Emergency Locking Retractors: Front Seatbelts Emergency Locking Retractors: Front And Rear Seatbelts Seatbelt Force Limiters: Front Seatbelts Seatbelt Pretensioners: Front Seatbelts Seatbelt Pretensioners: Front And Rear Seatbelts Seatbelt Warning Sensor: Driver And Passenger Seatbelts Second Row 3 - Point Stability Control Steering Wheel Mounted Controls Audio Steering Wheel Mounted Controls Cruise Controls Steering Wheel Mounted Controls Multi-Function Screen Controls Steering Wheel Mounted Controls Phone Steering Wheel Mounted Controls Voice Recognition Controls Suspension Stabilizer Bar (S): Front Suspension Stabilizer Bar (S): Rear Tachometer Trip Computer Adjustable Rear Headrests Audio - Antenna: Diversity Audio - Antenna: Mast Auto - Lock Body Side Reinforcements Side Impact Door Beams Braking Assist Braking Assist Hill Start Assist Cargo Area 12V Power Outlet Cargo Area Light Cargo Cover Retractable Center Console Front Console With Armrest And Storage Clock Compass Digital Odometer Door Courtesy Lights Doors Liftgate Window: Fixed Driver Information System Driver Seat Adjustable Lumbar Support: Power Driver Seat Power Adjustments: Recline Easy Entry Power Driver Seat Easy Entry Power Steering Wheel Electroluminescent Instrumentation Electronic Messaging Assistance With Read Function Electronic Messaging Assistance With Voice Recognition Exterior Mirrors Manual Folding External Temperature Display Floor Mat Material Carpet Floor Material Carpet Front 12V Power Outlet (2) Front Headrests Adjustable Front Suspension Classification: Independent Front Suspension Type: Macpherson Struts Fuel Economy Display Range Mirror Color Body - Color Number Of Front Headrests 2 Number Of Rear Headrests 3 Passenger Seat Adjustable Lumbar Support: Power Power Brakes Power Door Locks Anti-Lockout Feature Power Steering Power Windows: With Safety Reverse Reading Lights Front Reading Lights Rear Rear 12V Power Outlet Rear Bumper Color Body - Color Rear Seats 40-20-40 Split Bench Rear Seats Center Armrest: Folding With Storage Rear Seats Center Armrest: With Cupholders Rear Seats Rear Heat: Vents Rear Seats Reclining Rear Seats Sliding Rear Seats Split Folding Seats Front Seat Type: Bucket Tail And Brake Lights Led Trip Odometer 2 Vanity Mirrors Dual Illuminating Warnings And Reminders Lamp Failure Low Fuel Engine Oil Coolant Warnings And Reminders Maintenance Reminder Windows Front Wipers: Variable Intermittent Windows Laminated Glass: Acoustic Windows Lockout Button Windows Privacy Glass Windows Rear Defogger
The double - blind, placebo - controlled studies used the state - of - the - art force - plate analysis, a statistically significant number of dogs participated in the trial and showed significant improvement at a 95 % confidence level.
While the new update (as of 2014) doesn't increase the number of animals required (just 6 must complete the 6 - month adult trial), it does require better documentation of control groups and test observations, improves requirements for puppy food trials, and implements tighter controls on statistics used to interpret results.
There are a number of medical therapies that seem to help CLM / SM dogs with both pain management and scratching activity, but there are no controlled clinical trials published yet to objectively measure the efficacy / inefficacy of these treatments.
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A number of minor enhancements are recommended as a result of this pilot and we hope to be able to use the pilot data for an NHMRC grant application for a randomised controlled trial early next year.
Type of Study: Randomized controlled trial (block randomized within each of three stratification groups) Number of Participants: 98
These programs include the Nurse Family Partnership, 16,17 Healthy Families America, 18,19 Healthy Start, 20,21 Early Head Start, 22,23 the Comprehensive Child Development Program, 24 — 26 and Early Start.27, 28 All of these programs have been evaluated by using randomized control designs but findings from these trials have been mixed, with some programs showing benefits and others failing to show benefits.29, 30 In a recent review, Howard and Brooks - Gunn30 found that home - visiting programs had reported benefits for a number of outcomes, including child abuse, child health care, quality of home environment, parenting, parental depression, and childhood cognitive skills.
At the point of referral to the trial, families were randomized to either Early Start or control series based on a computer - generated series of random numbers, and no blinding to assignment was undertaken.
Group parenting programmes have been shown to have a positive impact on the mental health of children and parents in the short term.9 — 12 Positive results have been obtained from randomised controlled trials and other studies with parents of children with clinically defined behaviour disorders, 9,13,14 children at high risk of behaviour problems, 9,15 and to a lesser extent with normal populations.16, 17 They have also been obtained in trials of interventions for parents and children of different ages.18, 19 The number of trials carried out in the UK is small.13, 15,20,21 A recent systematic review concluded that these programmes are effective in the long term, 12 but most of the trials on which this review was based used a waiting list control design, and as a result outcome data are not reported on the control groups beyond 6 months.
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