Sentences with phrase «controlling cell identity»

Not exact matches

The specific pattern of epigenetic marks in a cell type specifies identity and this epigenetic control is vital to what makes our cells different, for example a skin cell from a liver cell, when they all contain the same genetic instructions.

Instead, the genetic identity of each subtype of cells — what makes those that control the quadriceps muscle different from those that control the calf muscle for instance — is also important.

Although the functional importance of TCF - 1 in T cells has been known for more than 25 years, the mechanism by which this protein controls T - cell identity remained unknown.

By controlling the transport of histones to our DNA, TLK and Asf1 ensure that the chromatin architecture and its information are copied correctly during cell division, so that cell identity is maintained,» explains Ilnaz Klimovskaia.

The Hippo pathway not only defines final tissue size by controlling developmental growth, but is also key to specifying stem cell identity and proliferation, to regeneration and tissue repair, as well as numerous cell fate decisions.

One is straightforward — during development, cells are assuming their identities and need precise control over protein production, so cells lacking a gene expression regulation mechanism are bound to have defects, particularly in the case of specialized cells like neurons.

This research, which was performed at the Roddenberry Center for Stem Cell Biology and Medicine at Gladstone, has also revealed the precise role of Sox2 as a master regulator that controls the identity of neural stem cells.

We are studying proteins called transcription factors that control skeletal cell identity and activity.

The fellow will drive a new project focusing on molecular mechanisms controlling the identity, self - renewal, and differentiation potential of skeletal stem cells.

Here we show that the transcription factor Gata6 controls the identity of the previously uncharacterized sebaceous duct (SD) lineage and identify the Gata6 downstream transcription factor network that specifies a lineage switch between sebocytes and SD cells.

With cell phones and blockchain technology, the creation of a self sovereign identity becomes a reality which individuals can control themselves.