Follistatin - like 1 (Fstl1) is a bone morphogenetic protein (BMP) 4 signaling antagonist in
controlling mouse lung development.
Not exact matches
The scientists conclude that in
mice «well - timed treatment with rIL - 27 improved
lung injury and accelerated recovery without affecting viral clearance» and continue «these data demonstrate that IL - 27 has a unique role in
controlling immunopathology without impacting on host defense, and might therefore represent a promising candidate for immunomodulatory therapy of viral pneumonia.»
Compared to a
control (left), epalrestat treatment (right) reduces the number of metastatic tumors (arrowheads) in the
lungs of
mice injected with human basal - like breast cancer cells.
Specifically, they determined that the immune systems in genetically altered
mice lacking the critically important calcium channel component STIM1 failed to
control TB, leading to severe
lung inflammation and premature death.
In
mice, each vagus nerve contains about 2,500 sensory neurons, a small number for a structure that innervates the heart,
lung, stomach and intestine and
controls different functions in these different organs.
«For example,
mouse mammary tumors shared a signaling pathway that is found in human
lung cancer and
controls how cells reproduce and move from one location to another.»
Surprisingly, while neither form of chemotherapy had any effect on the growth of these seeded metastases, Angiopoietin - 2 antibody treated
mice had significantly less metastases in the
lungs and in the bone and survived longer than untreated
control mice.
Mice injected with breast cancer cells making lots of a long strand of RNA called HOTAIR developed 10 times as many
lung tumors as
controls (left) did.
Mice infected with a resistant strain of tuberculosis that were treated with both SMARt - 420 and ethionamide also showed a significantly reduced bacterial load in their
lungs three weeks after infection compared to
controls, the authors report.
Dulling nerve cells in
mice's
lungs soothes irritated airways by easing inflammation and out - of -
control coughing, researchers report online June 25 in Neuron.
The first experiment is to measure metastatic
lung cancer in MMTV - PyMT transgenic
mice crossed with the POSTN Knock out
mice, and
controls, with focus on the role of periostin in metastatic progression.
After challenge, mean
lung virus titers were similar for the PBS
control challenged
mice of both
mouse strains (106.7 — 7.3 TCID50 / g
lung)(figure 7B).
We found no change in the total number of ILCs (Lin - CD45.2 + Thy1.2 + CD127 +) in the spleens,
lungs or livers of toxin treated
mice compared to
mice that were injected with vehicle
control (Fig 6A and S6A Fig).
Finally, to determine whether LARP7 KD also results in an increase in breast cancer metastasis in vivo, the T47D
control or shLARP7 - 2 cells were injected intravenously into the nude
mice, and
lung metastasis was examined 12 weeks later.